Datasheet1_Polo-like kinase (PLK) 5, a new member of the PLK family, serves as a biomarker to indicate anabatic tumor burden and poor prognosis for resectable non-small cell lung c... by Kaichao Wang (14335569)

“…Objective<p>A review argues that polo-like kinase 5 (PLK5) may be linked to unfavorable prognosis in non-small cell lung cancer (NSCLC) patients, which contradicts the discoveries from The Human Protein Atlas database (derived from TCGA analysis). …”

Recurrent dendritic spines are more stable in CA1 PNs that will become part of a representation. by Tim P. Castello-Waldow (9596799)

“…<p>(A) In vivo 2P time lapse of the same dendritic branch and spines over 5 d. …”

Epidural Hydromorphone for Postpartum Pain Management After Vaginal Delivery: A Randomized Clinical Trial by Yixing Lu (19234084)

“…</p><p dir="ltr"><b>Key Points</b></p><p dir="ltr"><b>Question</b></p><p dir="ltr">In women post-vaginal delivery, does the administration of epidural hydromorphone offer superior analgesia and enhance maternal satisfaction relative to a placebo (normal saline)?</p><p><br></p><p dir="ltr"><b>Findings</b></p><p dir="ltr">Epidural hydromorphone demonstrated a statistically significant reduction in postpartum pain scores, a decreased requirement for supplemental analgesics, and enhanced maternal satisfaction. …”

CA1 PNs that will become part of a representation display higher structural postsynaptic stability. by Tim P. Castello-Waldow (9596799)

“…<p>(A, B) The turnover fraction (A) and the fraction of dendritic spines gained (B) of prospective ArcTom+ neurons was lower than prospective ArcTom− neurons prior to EE (*<i>p</i> = 0.015, **<i>p</i> = 0.008 and *<i>p</i> = 0.02, **<i>p</i> = 0.009; permutation test; <i>N</i> = 10⁵ permutations). …”

Osmotically Rupturing Phagosomes in Macrophages Using PNIPAM Microparticles by Wenhao Cheng (6741377)

“…The rupture of macrophage phagosomes has been implicated in various human diseases and plays a critical role in immunity. However, the mechanisms underlying this process are complex and not yet fully understood. …”

Number of fish tagged by treatment and date. by April S. Cameron (8622711)

“…For all study fish, the presence of two intact sutures seven days post-surgery (generally associated with good suturing technique) was negatively correlated with survival. A generalized linear mixed effects model indicated that suture presence, increasing tagging temperature, and the presence of foreign material on sutures decreased survival by 0.56, 0.72 and 0.60 respectively. …”

Water, Sanitation, Hygiene, and Soil-Transmitted Helminth Infection: A Systematic Review and Meta-Analysis by Eric C. Strunz (542577)

“…Access to sanitation was associated with decreased likelihood of infection with any STH (OR 0.66, 95% CI 0.57–0.76), <i>T. trichiura</i> (OR 0.61, 95% CI 0.50–0.74), and <i>A. lumbricoides</i> (OR 0.62, 95% CI 0.44–0.88), but not with hookworm infection (OR 0.80, 95% CI 0.61–1.06). …”

A tropomyosin point mutant recapitulates the <i>rng8/9</i> deletion phenotype. by Omaya Dudin (3926825)

“…(G) Kymographs of Myo52-tdTomato showing multiple stable dots over >60s in <i>cdc8</i>^<i>E104A</i> mutant. (H) Myo51-3YFP fluorescence at the fusion site is decreased in <i>cdc8</i>^<i>E104A</i> mutant (N = 15); (***) P < 3 × 10⁻⁵, t-test. …”

Correlation in average site-level DNA methylation estimates between TMS and RRBS. by Amy Longtin (21409957)

Correlation in average site-level methylation for varying fragmentation methods. by Amy Longtin (21409957)

Correlation in average methylation at each site between plexing strategies. by Amy Longtin (21409957)

Correlation in average methylation at each site between input amounts. by Amy Longtin (21409957)

Matrix rigidity of MDA-MB-231 cells Representative collagen construct stress calculations from a single experiment for the initial, untreated stretch (A) and the deoxycholate treat... by Bridget Hindman (764612)

“…<p>For both, myosin II KD cell constructs had a decreased stiffness in response to strain. Because the stiffness calculation takes the cross sectional area of the constructs into account, and the IIA constructs are much larger, the difference between the parental and IIA KD constructs is enhanced when compared to the differences seen when the strain response is plotted as mN versus Strain (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0131920#pone.0131920.g006" target="_blank">Fig 6</a>). …”

Data_Sheet_1_Genetically Determined Lifestyle and Cardiometabolic Risk Factors Mediate the Association of Genetically Predicted Age at Menarche With Genetic Predisposition to Myoca... by Jilin Zheng (4029908)

“…Inverse variance weighted (IVW) MR analysis also showed that decrease in genetically predicted AAM was associated with higher genetically predicted alcohol intake frequency, current smoking behavior, higher waist-to-hip ratio, and higher levels of systolic blood pressure (SBP), fasting blood glucose, hemoglobin A1c (HbA1c), and triglycerides (TGs). …”

NHR-49 has a broad impact on fatty-acid desaturation in germline-less animals. by Ramesh Ratnappan (128556)

“…<p><b>A-C: The expression of fatty-acid desaturase genes in <i>nhr-49</i>;<i>glp-1</i> mutants.…”

a. How various statistical models account for modulation classification performance across the entire dataset. by Chris Scholes (3309477)

“…The underlying data for <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.g009" target="_blank">Fig 9a</a> is contained in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.s003" target="_blank">S2 Data</a> and the underlying data for <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.g009" target="_blank">Fig 9b</a>, <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.g009" target="_blank">9c</a>, <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.g009" target="_blank">9e</a>, and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.g009" target="_blank">9f</a> is contained in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003213#pbio.3003213.s004" target="_blank">S3 Data</a>.…”

Reduced model and effect of inhibitory failure on the response. by Abolhassan Behrouzvaziri (741985)

IMP semi-structured questions. by Nurul Bahirah Binte Adnan (15368814)

“…This study will provide the interventions’ feasibility and acceptability data for critical care healthcare professionals and will be used to inform a future, large-scale trial testing efficacy.</p></div>…”

Study flowchart. by Nurul Bahirah Binte Adnan (15368814)

“…This study will provide the interventions’ feasibility and acceptability data for critical care healthcare professionals and will be used to inform a future, large-scale trial testing efficacy.</p></div>…”

Pathology of colon tumors in DSS-treated HA-MAD1 mice. by Sarah E. Copeland (13951506)