Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media by Nanno F. A. W. Peek (8708166)

“…<div><p>Objective</p><p>Chronic suppurative otitis media (CSOM) is a chronic infectious disease with worldwide prevalence that causes hearing loss and decreased quality of life. …”

Table_1_Dietary patterns and diabetic microvascular complications risk: a Mendelian randomization study of European ancestry.docx by Xin Zhou (54275)

“…Summary statistics on dietary intakes were obtained from the UK biobank, and data on DMCs [diabetic retinopathy (DR), diabetic nephropathy (DN), and diabetic neuropathy (DNP)] were obtained from the FinnGen Consortium. A two-sample MR (TSMR) was conducted to explore the causal relationships of dietary habits with DMCs. …”

Table1_Identification and expression profiling of neuropeptides and neuropeptide receptor genes in a natural enemy, Coccinella septempunctata.DOCX by ShunDa Han (19822464)

“…Insect diapause is a physiological and ecological adaptative strategy acquired in adverse environments. …”

αν and β1 Integrins Mediate Aβ-Induced Neurotoxicity in Hippocampal Neurons via the FAK Signaling Pathway by Hai-Yan Han (417624)

“…Both the gene and protein expression of FAK increased after Aβ treatment. Interestingly, as the gene and protein levels of FAK decreased, the ρFAK protein expression markedly increased. …”

Table_4_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…</p>Methods<p>We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma cell differentiation and measures B cell survival or proliferation versus the formation of CD138+ plasmablasts. …”

One-Carbon Metabolism Pathway Gene Variants and Risk of Clear Cell Renal Cell Carcinoma in a Chinese Population by Lei Zhang (38117)

“…Compared with those carrying none variant allele, individuals carrying one or more variant alleles in these two genes had a statistically significantly decreased risk of ccRCC [<i>P</i> = 0.001, adjusted odds ratio (OR) = 0.73, 95% confidence interval (CI) = 0.06–0.90]. …”

Table_1_Vaccination completeness in children with rheumatic diseases: A longitudinal, observational multicenter cohort study in Switzerland.DOCX by Tatjana Welzel (11753417)

“…Annual non-live influenza vaccination was complete in 24.2% of children during IST; adherence decreased over the disease course.</p>Discussion<p>This study identified a low overall vaccination completeness in children with PRD. …”

Image_1_Aspirin Use on Incident Dementia and Mild Cognitive Decline: A Systematic Review and Meta-Analysis.tif by Hui Li (32376)

“…However, low-dose aspirin (75–100 mg/day) was associated with a decreased likelihood of developing dementia or MCI (the pooled RR = 0.75; 95% CI = 0.63–0.9; Ifor heterogeneity2 = 50.5%). …”

Table_1_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…</p>Methods<p>We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma cell differentiation and measures B cell survival or proliferation versus the formation of CD138+ plasmablasts. …”

Group B Streptococcal Infection of the Choriodecidua Induces Dysfunction of the Cytokeratin Network in Amniotic Epithelium: A Pathway to Membrane Weakening by Jeroen P. Vanderhoeven (531499)

“…To determine molecular pathways within fetal membranes (chorioamnion) associated with early choriodecidual infection that may progress to preterm premature rupture of membranes (PPROM), we examined the effects of a Group B Streptococcus (GBS) choriodecidual infection on chorioamnion in a nonhuman primate model. …”

Table_1_Low GNG12 Expression Predicts Adverse Outcomes: A Potential Therapeutic Target for Osteosarcoma.docx by Jinghong Yuan (11057892)

“…</p>Results<p>GNG12 expression decreased in osteosarcoma samples. GNG12 was a highly effective biomarker for osteosarcoma [area under the receiver operating characteristic (ROC) curve (AUC) = 0.920], and the results of our Kaplan–Meier analysis indicated that overall survival and progression-free survival differed significantly between low and high GNG-expression group (p < 0.05). …”

DataSheet1_The therapeutic efficacy of resveratrol for acute lung injury—A meta−analysis of preclinical trials.docx by Yin Tang (296253)

“…<p>Background: Resveratrol (RES) has a protective effect on acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). …”

Table_5_Identification and validation of a novel mitochondrion-related gene signature for diagnosis and immune infiltration in sepsis.xlsx by Shuai Hao (3367121)

“…Background<p>Owing to the complex pathophysiological features and heterogeneity of sepsis, current diagnostic methods are not sufficiently precise or timely, causing a delay in treatment. It has been suggested that mitochondrial dysfunction plays a critical role in sepsis. …”

DataSheet_1_Evidence of a conserved mammalian immunosuppression mechanism in Lutzomyia longipalpis upon infection with Leishmania.pdf by Erich Loza Telleria (8047055)

“…In L. longipalpis we found a similar effect: a genetically modified strain of Leishmania amazonensis over-expressing the metalloprotease GP63 induced a higher expression of the sand fly SHP indicating that the L. longipalpis SHP and parasite GP63 increased expressions are connected. …”

Normobaric Hyperoxia for Treatment of Pneumocephalus after Posterior Fossa Surgery in the Semisitting Position: A Prospective Randomized Controlled Trial by Bujung Hong (741557)

“…<div><p>Background</p><p>Supratentorial pneumocephalus after posterior fossa surgery in the semisitting position may lead to decreased alertness and other symptoms. We here aimed to prove the efficacy of normobaric hyperoxia on the absorption of postoperative pneumocephalus according to a standardized treatment protocol.…”

Supplemental Figure 4 FIP1C is a negative modulator of Akt and MAPK activation in an ErbB2-driven model from Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary... by Pierre-Luc Boulay (14924160)

DataSheet2_Investigating the effects of Liushen Capsules on the metabolome of seasonal influenza: A randomized clinical trial.docx by Qinhai Ma (11731726)

“…</p><p>Materials and methods: A randomized, double-blind, placebo-controlled clinical trial was designed in this study. …”

Predictors of decline in kidney function in the general population: a decade of follow-up from the Tehran Lipid and Glucose Study by Soroush Masrouri (14034201)

“…</p> <p>During 11.5 years of follow-up, 1471 (889 women) participants had incident KFD with a crude incidence rate of 192.1 (182.6–202.2) per 10,000 person-year. …”

DataSheet3_Investigating the effects of Liushen Capsules on the metabolome of seasonal influenza: A randomized clinical trial.docx by Qinhai Ma (11731726)

“…</p><p>Materials and methods: A randomized, double-blind, placebo-controlled clinical trial was designed in this study. …”

Identification of Chalcones as <i>Fasciola hepatica</i> Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach by Florencia Ferraro (3146766)

“…<div><p>Background</p><p>Increased reports of human infections have led fasciolosis, a widespread disease of cattle and sheep caused by the liver flukes <i>Fasciola hepatica</i> and <i>Fasciola gigantica</i>, to be considered an emerging zoonotic disease. …”