Image2_Severe pediatric asthma therapy: Omalizumab—A systematic review and meta-analysis of efficacy and safety profile.jpeg by Grazia Fenu (3439013)

“…The reported data on exacerbations showed an overall improvement in the exacerbation rate with a decreased use of inhaled steroids and some other minimal clinically important difference (MCID).…”

datasheet1_Anticancer Properties and Mechanisms of Singly-Protonated Dehydronorcantharidin Silver Coordination Polymer in a Bladder Cancer Model.zip by Changkuo Zhou (10180952)

“…The Ag-SP-DNC-induced bladder cancer cell apoptosis was significantly decreased following treatment with a broad caspase inhibitor, zVAD-fmk. …”

Protective Role of Morin, a Flavonoid, against High Glucose Induced Oxidative Stress Mediated Apoptosis in Primary Rat Hepatocytes by Radhika Kapoor (144345)

“…These apoptotic proteins initiated caspase activation, DNA fragmentation, chromatin condensation, increased apoptotic DNA content in glucose treated hepatocytes, suggesting mitochondria mediated apoptotic mode of cell death. Morin, a dietary flavonoid from <em>Psidium guajava</em> was effective in increasing the cell viability and decreasing the ROS level. …”

Data_Sheet_1_Depression, antidepressant use, and the risk of type 2 diabetes: a nationally representative cohort study.docx by Hyewon Kim (1788081)

“…</p>Results<p>In the group of DEP with antidepressants, although the risk of type 2 diabetes increased compared to HCs in a crude analysis, it decreased when comorbidity was adjusted for. …”

Supplementary Material for: Long-Term Neuropathological Changes Associated with Cerebral Palsy in a Nonhuman Primate Model of Hypoxic-Ischemic Encephalopathy by McAdams R.M. (4013723)

“…<p><b><i>Background:</i></b> Cerebral palsy (CP) is the most common motor disability in childhood, with a worldwide prevalence of 1.5-4/1,000 live births. …”

(a-c) shows the visit frequency of <i>M. semenowi</i> and <i>M. desertora</i> at three study sites. by Zhi Wang (193655)

“…During the day (12:30-15:00), activity decreases sharply, diving into the nest (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319087#pone.0319087.g003" target="_blank">Fig 3</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319087#pone.0319087.g004" target="_blank">Fig 4</a>). …”

A subsample of 501 candidate protected areas networks selected from near one point on the tradeoff curve (Fig 3). by Sarah Bauduin (6001238)

Data_Sheet_1_Resilience mediates the effect of the COVID-19 pandemic on mental health in a sample of adults in Panama.docx by Diana C. Oviedo (17399377)

“…</p>Discussion<p>These findings contribute to a growing body of research documenting the adverse effects of the COVID-19 pandemic on mental health and reveal potential mechanisms through which pandemic-related distress decreases resilience, thereby increasing symptoms of mental illness.…”

Hydrogen isotope fractionation in lipids as a function of growth rate in <i>E</i>. <i>huxleyi</i> chemostat cultures. by Julian P. Sachs (537931)

“…<p>(A) Fractionation factors (α) decreased, indicating greater ²H/¹H fractionation between lipids and extracellular water, as growth rates increased by 44‰ (div d^-1)^-1 for brassicasterol, and 79‰ (div d^-1)^-1 for myristic acid (C_14:0), 52‰ (div d^-1)^-1 for palmitic (C_16:0), and 32‰ (div d^-1)^-1 for stearic acid (C_18:0). …”

DataSheet1_SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans.PDF by Silvia Romero-Sanz (15774110)

“…</p><p>Methods: We have studied here the effects of submaximal SERCA inhibition in a chemical model of Parkinson’s disease (PD) induced in C. elegans worms by treatment with the mitochondrial complex I inhibitor rotenone. …”

Table_1_A double-blind randomized clinical trial on the suggestive effect of anxiety management questionnaires in dental emergencies.DOC by Carla Irene Benz (17947289)

“…</p>Conclusion<p>Within the limitations of the current study, a diagnostic tool of a standardized questionnaire for the assessment to assess personal coping strategies decreased state anxiety in comparison to a questionnaire assessing anxiety.…”

Curcumin Analog DM-1 in Monotherapy or Combinatory Treatment with Dacarbazine as a Strategy to Inhibit <i>In Vivo</i> Melanoma Progression by Fernanda Faião-Flores (392392)

“…Furthermore, melanoma tumors treated with DM-1 showed a preferential apoptotic intrinsic pathway by decreasing Bcl-2/Bax ratio. …”

Impact on Life Expectancy of Withdrawing Thiopurines in Patients with Crohn’s Disease in Sustained Clinical Remission: A Lifetime Risk-Benefit Analysis by Julien Kirchgesner (2819761)

“…<div><p>Objective</p><p>Long-term treatment with thiopurines is associated with a decreased risk of Crohn’s disease (CD) flare but an increased risk of various cancers depending on gender, age, and presence of extensive colitis. …”

Data_Sheet_1_A longitudinal study of fatty acid profiles, macronutrient levels, and plasmin activity in human milk.docx by Fanyu Meng (446249)

“…</p>Results<p>There was a significant influence of lactation stage on levels of protein and plasmin activities, but not on levels of fat and carbohydrate in term milk. …”

DEspR Roles in Tumor Vasculo-Angiogenesis, Invasiveness, CSC-Survival and Anoikis Resistance: A ‘Common Receptor Coordinator’ Paradigm by Victoria L. Herrera (383897)

“…<div><p><i>A priori</i>, a common receptor induced in tumor microvessels, cancer cells and cancer stem-like cells (CSCs) that is involved in tumor angiogenesis, invasiveness, and CSC anoikis resistance and survival, could underlie contemporaneous coordination of these events rather than assume stochasticity. …”

Iridium-Catalyzed Borylation of Primary Benzylic C–H Bonds without a Directing Group: Scope, Mechanism, and Origins of Selectivity by Matthew A. Larsen (1419943)

“…The benzylic C–H boryl­ation of methyl­arenes would be a method to form these products, but such reactions without neat methyl­arene or a directing group are unknown. …”

The potential impact of carboxylic-functionalized multi-walled carbon nanotubes on trypsin: A Comprehensive spectroscopic and molecular dynamics simulation study by Maryam Noordadi (5329340)

“…<div><p>In this study, we report a detailed experimental, binding free energy calculation and molecular dynamics (MD) simulation investigation of the interactions of carboxylic-functionalized multi-walled carbon nanotubes (COOH-f-MWCNTs) with porcine trypsin (pTry). …”

Reduced mechanical input induces a diminution of <i>Egr1</i> and <i>Scx</i> expression in adult tendons. by Ludovic Gaut (3335541)

“…The mRNA levels of <i>Egr1</i>, <i>Scx</i>, <i>Col1a2</i>, <i>Tgfb2</i> genes were decreased one or two weeks after Botox injection compared to physiological saline injection. …”

SAHA Treatment Reveals the Link between Histone Lysine Acetylation and Proteome in Nonsmall Cell Lung Cancer A549 Cells by Quan Wu (444646)

“…Suberoylanilide hydroxamic acid (SAHA) is a well-known pan HDAC inhibitor, and its clinical application (Vorinostat) has been demonstrated to treat nonsmall cell lung cancer (NSCLS). …”

Elevation-Related Variation in Leaf Stomatal Traits as a Function of Plant Functional Type: Evidence from Changbai Mountain, China by Ruili Wang (303054)

“…The relationship between stomatal characteristics and elevation differed among PFTs. In trees, SD decreased and SL increased with elevation; in shrubs and herbs, SD initially increased and then decreased. …”