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large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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60041
Data_Sheet_1_Aspartate α-decarboxylase a new therapeutic target in the fight against Helicobacter pylori infection.docx
Published 2022“…<p>Effective eradication therapy for Helicobacter pylori is a worldwide demand. Aspartate α-decarboxylase (ADC) was reported as a drug target in H. pylori, in an in silico study, with malonic acid (MA) as its inhibitor. …”
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60042
Data Sheet 1_Craving on the move: targeting smoking memories with a novel 3MDR–smoking cessation protocol.pdf
Published 2024“…Chronic smokers were randomly allocated to an active 3MDR-SC group (receiving 3MDR-SC with a working memory distractor task) (n = 42) or a control 3MDR-SC group (receiving 3MDR-SC with a non-distracting task) (n = 39). …”
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60043
DataSheet1_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.docx
Published 2024“…Background<p>Bullous pemphigoid (BP) is a rare, life-threatening autoimmune blistering disease with pruritus and tension blisters/bullous as the main clinical manifestations. …”
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60044
Table1_Lipids, lipid-lowering drugs and lateral epicondylitis of the humerus: a drug-targeted Mendelian randomization study.XLSX
Published 2024“…Lipoprotein lipase (LPL) enhancement is significantly associated with a decreased risk of LE (OR = 0.76, [95% CI, 0.65–0.90], p = 0.001). …”
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60045
Image_3_Protective Efficacy of Rhomboid-Like Protein 3 as a Candidate Antigen Against Eimeria maxima in Chickens.JPEG
Published 2021“…The third generation vaccine, including subunit and DNA vaccines, exhibited promising developmental prospects. In a previous study, we found rhomboid-like protein 3 of Eimeria maxima (EmROM3) was involved in infections by Eimeria species. …”
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60046
Efficacy and safety of adding gemtuzumab ozogamicin to conventional chemotherapy for adult acute myeloid leukemia: a systematic review and meta-analysis
Published 2021“…<p><b>Introduction:</b> Compared with the 3 + 7 regimen, the addition of gemtuzumab ozogamicin (GO) has improved survival in patients with acute myeloid leukemia (AML). We conducted a systematic review and meta-analysis to examine the overall efficacy and safety of GO in combination with conventional chemotherapy regimens in patients with AML.…”
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60047
Table1_Clinical, economic and humanistic outcomes of medication therapy management services: A systematic review and meta-analysis.DOCX
Published 2023“…<p>Background: Medication therapy management (MTM) services is a method that can effectively improve patients’ conditions, but the efficacy of economic and humanistic outcomes remain unclear. …”
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60048
Video1_Cause analysis of the liner dissociation of a customized reverse shoulder prosthesis based on finite element analysis.MOV
Published 2022“…The maximum DOD results of neutral initial humeral posture were 0.51% and 11.4% when the elastic modulus of the liner was increased and decreased by a factor of 10, respectively.</p><p>Conclusion: The humeral adduction impingement could lead to the deformation of the claw-shaped liner fixation structure, which might be one of the reasons for the liner dissociation. …”
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60049
Using audit and feedback to increase clinician adherence to clinical practice guidelines in brain injury rehabilitation: A before and after study
Published 2019“…</p><p>Design</p><p>A before and after study design.</p><p>Setting</p><p>A metropolitan inpatient brain injury rehabilitation unit.…”
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60050
Supplementary Material for: A New Generation Somatostatin-Dopamine Analogue Exerts Potent Antitumoral Actions on Pituitary Neuroendocrine Tumor Cells
Published 2019“…<b><i>Background:</i></b> Pituitary neuroendocrine tumors (PitNETs) represent approximately 15% of all intracranial tumors and usually are associated with severe comorbidities. Unfortunately, a relevant number of patients do not respond to currently available pharmacological treatments, that is, somatostatin analogs (SSAs) or dopamine-agonists (DA). …”
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60051
DataSheet_1_Immunomodulatory Role of Surfactant Protein-D in a Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Model.doc
Published 2022“…<p>Surfactant protein D (SP-D), a pattern recognition molecule, is emerging as a potent anti-tumoural innate immune defense molecule in a range of cancers. …”
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60052
Data_Sheet_1_Hepatocyte Nuclear Factor 3β Plays a Suppressive Role in Colorectal Cancer Progression.doc
Published 2019“…</p><p>Conclusions: The results show that HNF3β acts as a suppressor of colorectal cancer progression and decreased HNF3 β expression is closely related to the poor prognosis. …”
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60053
DataSheet_1_Assessing organ-level immunoreactivity in a rat model of sepsis using TSPO PET imaging.pdf
Published 2022“…<p>There is current need for new approaches to assess/measure organ-level immunoreactivity and ensuing dysfunction in systemic inflammatory response syndrome (SIRS) and sepsis, in order to protect or recover organ function. Using a rat model of systemic sterile inflammatory shock (intravenous LPS administration), we performed PET imaging with a translocator protein (TSPO) tracer, [<sup>18</sup>F]DPA-714, as a biomarker for reactive immunoreactive changes in the brain and peripheral organs. …”
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60054
Seroprevalence and risk factors of bluetongue virus in domestic cattle, sheep, goats and camels in Africa: a systematic review and meta-analysis
Published 2024“…<p>Bluetongue (BT) is a vector-borne disease affecting wild and domestic ruminants in many parts of the world. …”
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60055
Image 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.jpeg
Published 2025“…Background<p>Myasthenia gravis (MG) is a chronic autoimmune disease caused by autoantibodies attacking the neuromuscular junction. …”
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60056
Table_1_sVEGFR1 Is Enriched in Hepatic Vein Blood—Evidence for a Provisional Hepatic Factor Candidate?.docx
Published 2021“…Further research is needed to determine whether sVEGFR1 has a direct role in pulmonary microvascular remodeling and PAVMs in patients with palliated univentricular congenital heart disease.…”
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60057
Image2_Association between body fat distribution and age at menarche: a two sample Mendelian randomization study.pdf
Published 2024“…However, there are limited studies that explored the connection between body fat distribution and AAM, as well as a scarcity of Mendelian randomization (MR) studies.…”
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60058
Table_4_TMT proteomics analysis of a pseudocereal crop, quinoa (Chenopodium quinoa Willd.), during seed maturation.xlsx
Published 2022“…In this study, based on the investigation of morphological characteristics, a quantitative analysis of its global proteome was conducted using the combinational proteomics of tandem mass tag (TMT) labeling and parallel reaction monitoring (PRM). …”
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60059
Antitumor Effect of Malaria Parasite Infection in a Murine Lewis Lung Cancer Model through Induction of Innate and Adaptive Immunity
Published 2011“…Histological analysis of tumors from mice infected with malaria revealed that angiogenesis was inhibited, which correlated with increased terminal deoxynucleotidyl transferase-mediated (TUNEL) staining and decreased Ki-67 expression in tumors. Through natural killer (NK) cell cytotoxicity activity, cytokine assays, enzyme-linked immunospot assay, lymphocyte proliferation, and flow cytometry, we demonstrated that malaria infection provided anti-tumor effects by inducing both a potent anti-tumor innate immune response, including the secretion of IFN-γ and TNF-α and the activation of NK cells as well as adaptive anti-tumor immunity with increasing tumor-specific T-cell proliferation and cytolytic activity of CD8<sup>+</sup> T cells. …”
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60060
Table_1_The effect of montages of transcranial alternating current stimulation on occipital responses—a sham-controlled pilot study.docx
Published 2024“…Background<p>Transcranial alternative current stimulation (tACS) refers to a promising non-invasive technique to improve brain functions. …”