Image_6_Protective Efficacy of Rhomboid-Like Protein 3 as a Candidate Antigen Against Eimeria maxima in Chickens.JPEG by Chen Chen (6544)

“…The third generation vaccine, including subunit and DNA vaccines, exhibited promising developmental prospects. In a previous study, we found rhomboid-like protein 3 of Eimeria maxima (EmROM3) was involved in infections by Eimeria species. …”

Table_2_sVEGFR1 Is Enriched in Hepatic Vein Blood—Evidence for a Provisional Hepatic Factor Candidate?.docx by Andrew D. Spearman (10965657)

“…Further research is needed to determine whether sVEGFR1 has a direct role in pulmonary microvascular remodeling and PAVMs in patients with palliated univentricular congenital heart disease.…”

Image 2_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Methods<p>We conducted a retrospective cohort study using the MIMIC-IV database. …”

Table_5_TMT proteomics analysis of a pseudocereal crop, quinoa (Chenopodium quinoa Willd.), during seed maturation.xlsx by Zhi-Jun Shen (598229)

“…In this study, based on the investigation of morphological characteristics, a quantitative analysis of its global proteome was conducted using the combinational proteomics of tandem mass tag (TMT) labeling and parallel reaction monitoring (PRM). …”

Table_4_A Phylogenomic Study of Acanthamoeba polyphaga Draft Genome Sequences Suggests Genetic Exchanges With Giant Viruses.xlsx by Nisrine Chelkha (5722937)

“…Until recently, only the genome of a single Acanthamoeba castellanii Neff was available. …”

DataSheet_5_A Multi-Omics Study of Familial Lung Cancer: Microbiome and Host Gene Expression Patterns.xlsx by Ying Chen (9697)

Table_2_Total eosinophil count as a biomarker for therapeutic effects of upadacitinib in atopic dermatitis over 48 weeks.docx by Teppei Hagino (15658600)

“…Background<p>Atopic dermatitis (AD) is a chronic skin disease characterized by type 2-skewed immune responses, and significantly influenced by cytokines dependent on Janus kinases (JAKs). …”

Image_1_TMT proteomics analysis of a pseudocereal crop, quinoa (Chenopodium quinoa Willd.), during seed maturation.tif by Zhi-Jun Shen (598229)

“…In this study, based on the investigation of morphological characteristics, a quantitative analysis of its global proteome was conducted using the combinational proteomics of tandem mass tag (TMT) labeling and parallel reaction monitoring (PRM). …”

Data Sheet 1_What should we focus on in pregnancy complicated by pheochromocytoma? a bibliometric analysis (1990-2024).pdf by Shiyun Deng (21734750)

“…Purpose of review<p>The incidence of pheochromocytoma and paraganglioma (PPGL) in pregnancy is extremely low, yet it poses a significant threat to maternal and fetal safety. …”

DataSheet2_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.xlsx by Xiang Li (114679)

“…Background<p>Bullous pemphigoid (BP) is a rare, life-threatening autoimmune blistering disease with pruritus and tension blisters/bullous as the main clinical manifestations. …”

Image3_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…</p>Results<p>IVW analysis revealed that genetically decreased serum MMP-2 level were causally associated with a high risk of DN (OR = 0.88, 95% CI: 0.79-0.99, P = 0.026). …”

Supplementary Material for: GSK-3β as a potential coordinator of anabolic and catabolic pathways in hepatitis C virus insulin resistance by Hollinger F.B. (17727708)

“…Results: We show that IRS-1 Ser312, Beclin-1, protein conjugate Atg12-Atg5 or GS Ser641 are upregulated early in infection by activating the same pathways utilized for persistent infection; Bcl-XL, an inhibitor of both autophagy and apoptosis, is present in a core-complex with IRS-1 Ser312 and Beclin-1 during progression of IR; AMPK level remains the same in infected cells where it is activated by phosphorylation at Thr172 concomitant with increased autophagy, a hallmark of catabolic conditions; an mTOR level that promotes anabolism is increased rather than decreased under an expanded autophagy; hypophosphorylation of translational repressor 4E-BP1 downstream of mTOR is suggestive of reduced protein synthesis; and β-catenin is upregulated but not phosphorylated suggesting indirectly our previous contention that its kinase, GSK-3β, is mostly in an inactive state. …”

Data_Sheet_1_TCR Repertoire as a Novel Indicator for Immune Monitoring and Prognosis Assessment of Patients With Cervical Cancer.docx by Jin-Huan Cui (3752875)

“…<p>There is increasing evidence that deep sequencing-based T cell repertoire can sever as a biomarker of immune response in cancer patients; however, the characteristics of T cell repertoire including diversity and similarity, as well as its prognostic significance in patients with cervical cancer (CC) remain unknown. …”

Image_3_Longitudinal Links Between Media Use and Focused Attention Through Toddlerhood: A Cumulative Risk Approach.pdf by Noa Gueron-Sela (9590204)

“…In the current study, we aimed to move beyond the focus on isolated aspects of media use to a comprehensive assessment of both direct and indirect media use and practices in early childhood. …”

Data_Sheet_1_Genetic associations between ULK3 and epilepsy: a two-sample Mendelian randomization study.xlsx by Baolai Liu (19369291)

“…</p>Results<p>Our MR analyses revealed a causal relationship where an increased level of ULK3 was associated with a decreased risk of focal epilepsy (odds ratio = 0.92, 95% confidence interval: 0.86–1.00, p = 0.041). …”

FIGURE 3 from Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance by William Echavidre (17597592)

“…Proliferation rates are expressed as a percentage of day 0. Three independent experiments were performed, and data are presented as mean ± SEM. …”

Table1_Association between body fat distribution and age at menarche: a two sample Mendelian randomization study.docx by Peng Xue (219948)

“…However, there are limited studies that explored the connection between body fat distribution and AAM, as well as a scarcity of Mendelian randomization (MR) studies.…”

An invisible villain: high perceived stress, its associated factors, and possible consequences in a population-based survey in southern Brazil by Lauro Miranda Demenech (6698138)

“…Methods This was a population-based cross-sectional study carried out in 2016 with adults aged 18 years or older in a municipality in southern Brazil. …”

DataSheet_1_Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach.pdf by Rebecca Ingelfinger (9341330)

“…Here, we explored the pharmacological activity of six lichen extracts (Evernia prunastri, Pseudevernia furfuracea, Umbilicaria pustulata, Umbilicaria crustulosa, Flavoparmelia caperata, Platismatia glauca) in the context of cancer and inflammation using a comprehensive set of 11 functional and biochemical in vitro screening assays. …”

Image_7_A Phylogenomic Study of Acanthamoeba polyphaga Draft Genome Sequences Suggests Genetic Exchanges With Giant Viruses.TIF by Nisrine Chelkha (5722937)

“…Until recently, only the genome of a single Acanthamoeba castellanii Neff was available. …”