table2_Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes.pdf by Raju Khatri (4283260)

“…In contrast, PRH did not alter UGT2B7 mRNA levels or protein concentrations in SCHH, and formation of the UGT2B7-derived labetalol glucuronide metabolite was decreased following PRH exposure. Our findings demonstrate that PRH alter expression and function of UGT proteins in an isoform-specific manner and increase UGT1A1-mediated labetalol metabolism in human hepatocytes by inducing UGT1A1 protein concentrations. …”

DataSheet_1_Creation of a Single Cell RNASeq Meta-Atlas to Define Human Liver Immune Homeostasis.docx by Brittany Rocque (11144175)

“…Single-cell RNA sequencing (scRNA seq) is a powerful approach to generate highly dimensional transcriptome data to understand cellular phenotypes. …”

Most Merkel cell innervating Ret⁺ fibers are lost in <i>TrkA^−/−</i> mice. by Jingwen Niu (538210)

“…G, Pie chart showing that within the <i>Ret^CFP/+; TrkA</i>^{−<i>/</i>−} background, 70% of the touch domes have no CFP⁺ fiber innervation, while 30% of touch domes receive greatly decreased innervation of CFP⁺ fibers. …”

DataSheet1_Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells.PDF by Luca Hegedüs (12274409)

“…<p>Malignant pleural mesothelioma (MPM) is a rare type of cancer with a grim prognosis. So far, no targetable oncogenic mutation was identified in MPM and biomarkers with predictive value toward drug sensitivity or resistance are also lacking. …”

Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf by Yu Xu (52257)

“…Mice subjected to middle cerebral artery occlusion (MCAO) exhibited significant reductions in infarct size and brain edema, prolonged post-MCAO survival, and improved behavioral outcomes following aCD19 Ab treatment. Transmission electron microscopy (TEM) and Computed Tomography Angiography (CTA) results revealed a reduction in microvascular endothelial edema, decreased mitochondrial damage in neurons, reduced neuronal apoptosis, and a favorable reconstruction of the cerebral vascular network. …”

Data_Sheet_1_Effectiveness of acupuncture as auxiliary combined with Western medicine for epilepsy: a systematic review and meta-analysis.docx by Hua Xue (469826)

“…The methodological quality of the studies was assessed using the Cochrane Handbook for Systematic Reviews of Interventions.</p>Results<p>A total of 17 RCTs involving a total of 1,389 participants were included. …”

Image4_Downregulated Dual-Specificity Protein Phosphatase 1 in Ovarian Carcinoma: A Comprehensive Study With Multiple Methods.PNG by Zi-Qian Liang (12650434)

“…Finally, DUSP1 may have a targeting relation with paclitaxel and participate in MAPK signaling pathways.…”

Image_3_A high trans-zeatin nucleoside concentration in corms may promote the multileaf growth of Amorphophallus muelleri.tif by Zhiqin Xue (13915116)

“…It is worth mentioning that N6-(Δ2-isopentenyl) adenosine (iP)-type cytokinins have a high content in corms in the dormant period that significantly decreases after the first leaf sprouting stage, which is completely different from the trend of tZR. …”

Image3_Comprehensive analysis of the cuproptosis-related gene DLD across cancers: A potential prognostic and immunotherapeutic target.TIF by Weiguang Yang (1440028)

“…<p>DLD is a key gene involved in “cuproptosis,” but its roles in tumor progression and immunity remain unclear. …”

Image_1_Application of a multispecies probiotic reduces gastro-intestinal discomfort and induces microbial changes after colonoscopy.jpeg by Joachim Labenz (14348019)

“…<p>Even after decades of research and pharmaceutical development, cancer is still one of the most common causes of death in the western population and the management of cancer will remain a major challenge of medical research. One of the most common types of cancer is colorectal cancer (CRC). …”

Image 2_Prognostic prediction and treatment options for gastric signet ring cell carcinoma: a SEER database analysis.tif by Chengqing Yu (19919697)

“…Compared with other subtypes (non-SRCC) such as adenocarcinoma, SRCC usually exhibits a more aggressive biological behavior. Therefore, studying the prognostic differences and factors associated with SRCC is essential to improve the accuracy of diagnosis and prognosis. …”

Table_1_Application of a multispecies probiotic reduces gastro-intestinal discomfort and induces microbial changes after colonoscopy.xlsx by Joachim Labenz (14348019)

“…<p>Even after decades of research and pharmaceutical development, cancer is still one of the most common causes of death in the western population and the management of cancer will remain a major challenge of medical research. One of the most common types of cancer is colorectal cancer (CRC). …”

Table_1_A high trans-zeatin nucleoside concentration in corms may promote the multileaf growth of Amorphophallus muelleri.xlsx by Zhiqin Xue (13915116)

“…It is worth mentioning that N6-(Δ2-isopentenyl) adenosine (iP)-type cytokinins have a high content in corms in the dormant period that significantly decreases after the first leaf sprouting stage, which is completely different from the trend of tZR. …”

Table_1_Examining the relationship between CDAI and frailty and its manifestation in Parkinson’s disease: a cross-sectional study.DOCX by Zhaohao Zeng (16989468)

“…Vitamin A, C, E, selenium and carotenoids exhibited J-shaped relationships where frailty risk decreased below intake thresholds of 1093.04 μg, 161.53 mg, 13.66 mg, 109.99 μg, and 5057.50 μg, respectively. …”

Image_7_A longitudinal study of the brain structure network changes in HIV patients with ANI: combined VBM with SCN.JPEG by Fan Xu (161740)

“…During the follow-up period, a decline in GMV in the right fusiform gyrus (FWE, p < 0.05) and a reduction in node efficiency (Ne) in the triangular part of the inferior frontal gyrus were noted compared with baseline measurements (FDR, p < 0.05). …”

Table 1_Prevalence and characteristics of participants in Dry January 2024: findings from a general population survey in France.docx by Louis-Ferdinand Lespine (15302470)

“…Background<p>Dry January is a one-month alcohol abstinence challenge for the general population running since 2013 in the United Kingdom, and 2020 in France. …”

Table 1_Prognostic prediction and treatment options for gastric signet ring cell carcinoma: a SEER database analysis.docx by Chengqing Yu (19919697)

“…Compared with other subtypes (non-SRCC) such as adenocarcinoma, SRCC usually exhibits a more aggressive biological behavior. Therefore, studying the prognostic differences and factors associated with SRCC is essential to improve the accuracy of diagnosis and prognosis. …”

Image_1_Application of a multispecies probiotic reduces gastro-intestinal discomfort and induces microbial changes after colonoscopy.jpeg by Joachim Labenz (14348019)

“…<p>Even after decades of research and pharmaceutical development, cancer is still one of the most common causes of death in the western population and the management of cancer will remain a major challenge of medical research. One of the most common types of cancer is colorectal cancer (CRC). …”

Table2_Long-term monitoring of fish in a freshwater reservoir: Different ways of weighting complex spatial samples.DOCX by Gashaw C. Tesfaye (14249717)

“…All approaches consistently showed an increasing trend in whole-reservoir fish abundance and a decreasing trend in biomass over the study period. …”

Data_Sheet_2_Histomorphometric Quantitative Evaluation of Long-Term Risedronate Use in a Knee Osteoarthritis Rabbit Model.PDF by Silvia Fernández-Martín (9589685)

“…The research results demonstrated that the experimental animal model induced osteoarthritic changes in the operated joints, showing an increased cartilage thickness and fibrillation associated with underlying subchondral bone thinning and decreased trabecular bone quality. These changes were especially highlighted in the medial tibial compartments as a possible response to surgical instability. …”