Microdialysis Assessment of Cerebral Perfusion during Cardiac Arrest, Extracorporeal Life Support and Cardiopulmonary Resuscitation in Rats – A Pilot Trial by Andreas Schober (631954)

“…During VF-CA central nervous glucose decreased (0.32±0.1mmol/l to 0.04±0.01mmol/l; p<0.001) and showed a significant rise (0.53±0.1;p<0.001) after resuscitation. …”

Table_7_Inflammatory cytokines and stroke and its subtypes: a genetic correlation and two-sample Mendelian randomization study.XLSX by Yu Guo (102701)

“…Our findings suggest that decreased IL-17 levels could potentially be linked to a higher likelihood of intracerebral hemorrhage (ICH) (OR = 0.51, 95% CI: 0.28–0.93, p = 0.028). …”

Table_8_Dried fruit intake causally protects against low back pain: A Mendelian randomization study.DOCX by Jian Huang (7250)

Table1_Risk of drug-induced angioedema: a pharmacovigilance study of FDA adverse event reporting system database.xlsx by Maoxia Fan (16914033)

“…After categorizing the drugs, the strongest positive signal was observed in the antithrombotic agents [ROR (95% CI): 22.53 (21.16–23.99)], following that, cardiovascular drugs [ROR (95% CI): 9.17 (8.87–9.48)], antibiotics [ROR (95% CI): 6.42 (5.91–6.96)], immunosuppressors [ROR (95% CI): 5.95 (5.55–6.39)], anti-inflammatory analgesics [ROR (95% CI): 4.65 (4.45–4.86)], antiallergic drugs [ROR (95% CI): 4.47 (3.99–5)], antiasthmatics [ROR (95% CI): 2.49 (2.14–2.89)], blood sugar control drugs [ROR (95% CI): 1.65 (1.38–1.97)], and digestive system drugs [ROR (95% CI): 1.59 (1.45–1.74)] exhibited progressively decreasing ROR values.</p>Conclusion<p>Many medications are associated with a high risk of angioedema. …”

DataSheet1_Daily Variations in pCO2 and fCO2 in a Subtropical Urbanizing Lake.docx by Rongjie Yang (1493281)

“…<p>The transfer of CO₂ from lakes to the atmosphere is a component of the global carbon equilibrium, while the quantification of the CO₂ partial pressure (pCO₂) is critical for exploring the contribution of freshwater CO₂ emissions in the regional/global carbon budget. …”

Table_1_Retinal changes in patients with idiopathic inflammatory myopathies: A case-control study in the MyoCite cohort.docx by Rachna Aggarwal (14193875)

“…Therefore, we explored retinal changes in patients with Idiopathic inflammatory myopathies (IIM) as a surrogate for vascular health.</p>Methods<p>Adult and Juvenile IIM patients (2017 ACR/EULAR criteria), visiting a tertiary care center in 2021 were enrolled for detailed ophthalmic examination in comparison with healthy controls (HC). …”

Resveratrol reduces <i>miR-21</i> expression and increases PDCD4 and maspin expression. <i>A,</i> by Sandeep Sheth (112040)

“…<b><i>B,</i></b> Resveratrol decreases <i>miR-21</i> levels in a dose-dependent manner. …”

Image_1_Negative Association of Interleukin-33 Plasma Levels and Schistosomiasis Infection in a Site of Polyparasitism in Rural Cameroon.TIF by Severin Donald Kamdem (8069741)

“…Although Plasma IL-33 showed a minimal negative risk for schistosomiasis infection (AOR 0.99; 95% CI 0.97–1.01), S. mansoni infected participants had lower levels of plasma IL-33 (p = 0.003) which decreased significantly as eggs burdens increased (p = 0.01) with a negative Pearson coefficient of r = −0.22. …”

Image2_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.JPEG by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Table1_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.xlsx by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

DataSheet1_Prescribing Intensity in Resistance Training Using Rating of Perceived Effort: A Randomized Controlled Trial.XLSX by Yael Boxman-Zeevi (12478485)

“…For instance, trainees can reach a specific RPE value by modifying the number of repetitions, lifted loads, or other training variables. …”

Table2_A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments.docx by Xiao-Hua Li (1508020)

“…The significant lipid-lowering drugs after MR analyses were further evaluated for their effects on bone mineralization using a dexamethasone-induced OP zebrafish model.</p><p>Results: The first step MR analysis found that the higher expression of four genes (HMGCR, NPC1L1, PCSK9 and PPARG) was significantly associated with a lower LDL-C level. …”

Table_9_Inflammatory cytokines and stroke and its subtypes: a genetic correlation and two-sample Mendelian randomization study.XLSX by Yu Guo (102701)

“…Our findings suggest that decreased IL-17 levels could potentially be linked to a higher likelihood of intracerebral hemorrhage (ICH) (OR = 0.51, 95% CI: 0.28–0.93, p = 0.028). …”

DataSheet1_A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays.docx by Ting-Hsuan Sun (9385940)

“…Using data from the TWB 2.0 custom Axiom array, we adopted an advanced normalization adjustment to prevent false calls caused by splitting the cluster and a rare het adjustment which decreases false calls in rare variants. …”

Table_4_Dried fruit intake causally protects against low back pain: A Mendelian randomization study.DOCX by Jian Huang (7250)

Data_Sheet_1_Blood Purification in Severe and Critical COVID-19 Patients: A Case Series of 5 Patients.docx by Hongjun Chen (132548)

“…<p>Objective: The ongoing coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a worldwide pandemic. Currently, supportive care measures remain the standard of care for severe and critical COVID-19 patients, such as ventilation oxygenation, fluid management and blood purification. …”

Table_3_Dried fruit intake causally protects against low back pain: A Mendelian randomization study.DOCX by Jian Huang (7250)

Table_1_Efficacy and Safety of Tacrolimus Therapy for a Single Chinese Cohort With Very-Late-Onset Myasthenia Gravis.DOCX by Yiming Zheng (3921866)

“…Background and Purpose<p>Previous studies have found tacrolimus to be a favorable drug for treating different types of myasthenia gravis (MG), but few have focused on very-late-onset MG (VLOMG). …”

Datasheet4_Assessing disparities through missing race and ethnicity data: results from a juvenile arthritis registry.pdf by Katelyn M. Banschbach (19204348)

“…Black patients had a significantly higher odds ratio of having a clinical juvenile arthritis disease activity score (cJADAS10) of ≥5 at first follow-up compared with White patients. …”

Table 1_Temporal trends and geographic disparities in thyroid cancer burden: a global analysis from 1990 to 2021.doc by Zuzhi Zhao (21724217)

“…This study aimed to update the evaluation of thyroid cancer prevalence, incidence, mortality, and Disability–Adjusted Life Years (DALYs) rates from 1990 to 2021, with a focus on integrating prevalence data. Analyses were stratified by gender, age, and Socio–Demographic Index (SDI) at global, regional, and national levels.…”