DM newborn (Day 1) mouse kidney showed nephrogenesis period between 3rd and 4th stages, revealing less demarcated cortical labyrinth and medullary rays, as well as decreased fetal glomeruli and convoluted tubules in deeper cortical and juxtamedullary regions with scattered ‘-shaped’bodies, residual advancing ampullae of ureteric buds, diminished branching of developing convolution (100×) (<b>Fig.4a</b>). by Ching-Yuang Lin (280489)

Secondary Dyslipidemia In Obese Children - Is There Evidence For Pharmacological Treatment? by Graciane Radaelli (5186603)

“…Objective: Systematic review of randomized clinical trials of statin use to treat children and adolescents with dyslipidemia secondary to obesity. Methods: We performed a search in PubMed, EMBASE, Bireme, Web of Science, Cochrane Library, SciELO, and LILACS for data to evaluate the effect of statins on: improvement of surrogate markers of coronary artery disease in clinical outcomes of adulthood; increased serum levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and apolipropotein B (APOB); and decreased serum levels of high-density lipoprotein cholesterol (HDL-C) from inception to February 2016. …”

Secondary Dyslipidemia In Obese Children - Is There Evidence For Pharmacological Treatment? by Graciane Radaelli (5186603)

“…Objective: Systematic review of randomized clinical trials of statin use to treat children and adolescents with dyslipidemia secondary to obesity. Methods: We performed a search in PubMed, EMBASE, Bireme, Web of Science, Cochrane Library, SciELO, and LILACS for data to evaluate the effect of statins on: improvement of surrogate markers of coronary artery disease in clinical outcomes of adulthood; increased serum levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and apolipropotein B (APOB); and decreased serum levels of high-density lipoprotein cholesterol (HDL-C) from inception to February 2016. …”

Clazosentan: First Approval by Arnold Lee (8502113)

“…ET_A receptor inhibition by clazosentan decreases ET-related cerebral vasospasm, which may occur after an aneurysmal subarachnoid haemorrhage. …”

Annexin A1 and A2: Roles in Retrograde Trafficking of Shiga Toxin by Lionel Tcatchoff (152994)

“…Knockdown of annexin A1 increases Golgi transport of Stx, whereas knockdown of annexin A2 slightly decreases the same transport step. …”

Supplementary Material for: Association of <i>AHSG</i> Gene Polymorphisms and Aortic Stiffness in Peritoneal Dialysis Patients by Jung J.Y. (4122502)

“…Decreased serum concentration of fetuin-A is independently related to all-cause and cardiovascular mortality in dialysis patients. …”

Table 2_Tissue-specific effects of bacterial PncA overexpression on NAD+ metabolism and aging in mice: implications for tissue-specific aging interventions.xls by Fengjiao Huo (15993086)

“…Overexpressing the bacterial nicotinamidase PncA in mice increased NAD⁺ levels in the liver and kidneys but decreased levels in the heart and hippocampus. …”

Lack of HP1a or POF shifts the enrichment pattern of RNA pol II on chromosome 4. by Nicole C. Riddle (134424)

“…Scatter plot showing enrichment of RNA pol II at the promoter region (+/−500 bp of TSS, top panel) and gene body (bottom panel). In both HP1a and POF mutants, the RNA pol II enrichment decreases significantly only in the gene body. …”

The effect of eEF1A mutations on TBSV repRNA accumulation in yeast. by Zhenghe Li (238151)

“…(C) Critical eEF1A residues for tombusvirus replication. Three novel mutants of eEF1A were identified, which exhibited increased tombusvirus replication (V301D, L374V/N377K, and F413L; yellow balls) while the new A76V and the previously identified T22S exhibited decreased tombusvirus replication (green balls). …”

Zinc exposure attenuates NR2A clusters and currents. by Jia Zhu (135506)

“…(B) and (C) show the quantification data of (A). Both the number and mean intensity of NR2A clusters significantly decreased after zinc treatment. …”

Table 1_Tissue-specific effects of bacterial PncA overexpression on NAD+ metabolism and aging in mice: implications for tissue-specific aging interventions.docx by Fengjiao Huo (15993086)

“…Overexpressing the bacterial nicotinamidase PncA in mice increased NAD⁺ levels in the liver and kidneys but decreased levels in the heart and hippocampus. …”

SURF6 knockdown and overexpression change the profile of pre-rRNA in HeLa cells as well as in HCT116 p53+ and HCT116 p53- cells. by Anastasiia Moraleva (16548419)

Table 1_Epidemiology and genetic characteristics of coxsackievirus A16 associated with hand-foot-mouth disease in Hangzhou city, Zhejiang province from 2021 to 2024.docx by Qihao Xu (5513795)

“…The detected number of CV-A16 began to rise in March, peaked in May–August, and then decreased in September. …”

Retinol and mineral status in grazing foals during the dry season by Maria Lindomárcia Leonardo da Costa (12802135)

“…Beta-carotene in grass showed a downward trend over time from 38.53 to 0.09 mg/kg of dry matter. …”

Data Sheet 1_Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis.pdf by Yan Liu (25061)

“…In vitro, experiments showed that semaglutide decreased the expression of S100A9 by activating the Protein Kinase C(PKC) pathway, thus inhibiting ferroptosis in cardiomyocytes.…”

Data Sheet 2_Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis.docx by Yan Liu (25061)

“…In vitro, experiments showed that semaglutide decreased the expression of S100A9 by activating the Protein Kinase C(PKC) pathway, thus inhibiting ferroptosis in cardiomyocytes.…”

Table 1_Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis.docx by Yan Liu (25061)

“…In vitro, experiments showed that semaglutide decreased the expression of S100A9 by activating the Protein Kinase C(PKC) pathway, thus inhibiting ferroptosis in cardiomyocytes.…”

Image 1_Epidemiology and genetic characteristics of coxsackievirus A16 associated with hand-foot-mouth disease in Hangzhou city, Zhejiang province from 2021 to 2024.jpeg by Qihao Xu (5513795)

“…The detected number of CV-A16 began to rise in March, peaked in May–August, and then decreased in September. …”

Supplementary Material for: The Designer Antimicrobial Peptide A-hBD-2 Facilitates Skin Wound Healing by Stimulating Keratinocyte Migration and Proliferation by Mi B. (5999321)

“…<b><i>Conclusion:</i></b> Our data suggest that A-hBD-2 may be a promising candidate therapy for wound healing.…”

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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