Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) by Saragusty, Joseph

“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in <em>Leishmania donovani</em> by Bhavna Chawla (176976)

“…<div><p>Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (<em>N</em>^€-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, <em>Leishmania donovani,</em> which causes visceral leishmaniasis. …”

Efmoroctocog Alfa: A Review in Haemophilia A by James E. Frampton (4995257)

“…</p> <p><b> </b></p> <p><b>Authorship and Conflict of interest</b> James E. Frampton is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. …”

Chemoresistance of Human Monocyte-Derived Dendritic Cells Is Regulated by IL-17A by Selma Olsson Åkefeldt (282869)

“…Immature dendritic cells were CD40^lowHLADR^low CD1a⁺ MCL1⁺, did not express CD14, CD68 or BCL2A1, and displayed a short 2-day lifespan. …”

Porcine Coro1A inhibit <i>H.parasuis</i> induced NF-κB activation. by Chong Liu (450204)

“…<p>(A) PK-15 cells were transfected with pNF-κB-luc (0.2 µg) and pRL-TK (0.05 µg), then cells were control-inoculated, live or heat-killed <i>H.parasuis</i> (10⁷ CFU) inoculated. …”

Reduction of NF-κB activation when porcine Coro1A was overexpressed. by Chong Liu (450204)

“…<p>(A) PK-15 cells were co-transfected with the pNF-κB-luc reporter plasmid (0.2 µg), pRL-TK plasmid (0.05 µg), along with 0.6 µg of the expression plasmid encoding porcine Coro1A protein. …”

HilD-activation results in a growth defect. by Doaa Osama Saleh (16353149)

“…Representative images are shown in the right panel. the same strains as in (A) were analysed. (C) Time-lapse microscopy analysis reveals a decreased cell elongation rate (left), a decrease in the maximal cell length (middle) as well as decreased length elongation during a division cycle (right) upon HilD induction. …”

Comparison of hatched blastocyst rates in Groups A and B. by Ayaka Fujishima (21221913)

Data_Sheet_1_Parental perceptions and the 5C psychological antecedents of COVID-19 vaccination during the first month of omicron variant surge: A large-scale cross-sectional survey... by Shuliweeh Alenezi (11671658)

“…Background<p>With the rapid surge of SARS-CoV-2 Omicron variant, we aimed to assess parents' perceptions of the COVID-19 vaccines and the psychological antecedents of vaccinations during the first month of the Omicron spread.</p>Methods<p>A cross-sectional online survey in Saudi Arabia was conducted (December 20, 2021-January 7, 2022). …”

Lack of i6A37 is not responsible for <i>maf1-</i>antisuppression phenotype. by Aneeshkumar G. Arimbasseri (840654)

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 4 by Nivedita Arora (3743413)

“…</b> Treatment with 100nM triptolide decreased the mRNA expression of Sp1, HSF1 and HSP70 in MKN28 and MKN45 gastric adenocarcinoma cells in a time (24–48 hours) dependent manner. …”

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 1 by Nivedita Arora (3743413)

“…</b> Treatment of moderately differentiated gastric adenocarcinoma cell line, MKN28 with triptolide decreases viability in a dose (25–100nM) as well as time (24–72 hours) dependent manner. …”

Data_Sheet_1_A Tool for Computation of Changes in Na+, K+, Cl− Channels and Transporters Due to Apoptosis by Data on Cell Ion and Water Content Alteration.ZIP by Valentina E. Yurinskaya (2735836)

“…New experimental data for staurosporine-induced apoptosis of human lymphoma cells U937 have been obtained: the time course of changes in cellular K⁺, Na⁺, Cl⁻, and water content, as well as Rb⁺ fluxes as a marker of the Na/K pump activity. Using a newly developed computational tool, we found that alteration of ion and water balance was associated with a 55% decrease in the Na⁺/K⁺-ATPase rate coefficient over a 4-h period, with a time-dependent increase in potassium channel permeability, and a decrease in sodium channel permeability. …”

Statistics of three drug combination datasets were listed, including the number of drugs, principal drugs, adjuvant drugs, known synergistic combinations (A), and drug pairs withou... by Xing Chen (140292)

Protective effects of 0.2 μM cyclosporine A (CsA) on the sensitivity of mPTP opening under de-energized conditions. by Gonçalo C. Pereira (9022700)

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 2 by Nivedita Arora (3743413)

Changes in the replacement desorption amount caused by a single penetrant. by Dan Zhao (285025)

Variation in gas relief-pressure desorption by a single penetrant. by Dan Zhao (285025)

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 3 by Nivedita Arora (3743413)

Effect of mask exposure on global visual cue use as a function of social interaction in Study 2. by Elyssa M. Barrick (11552817)