Supplementary Material for: Temozolomide Alone or Combined with Capecitabine for the Treatment of Advanced Pancreatic Neuroendocrine Tumor by deMestier L. (6952859)

“…<b><i>Results:</i></b> TEM and TEM-CAP were administered to 38 patients and 100 patients, respectively, with a median age of 58 years. The patients in the TEM group more often had hormonal syndromes (<i>p</i> = 0.03), a longer median delay to diagnosis (<i>p</i> = 0.001), and a higher number of pretreatment lines (<i>p</i> < 0.001). …”

DataSheet_1_Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe.pdf by Kamil Demircan (12978935)

“…</p>Discussion<p>The data support the potential relevance of a decrease in serum Se and Zn for survival in COVID-19 across Europe. …”

Image_4_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.tif by Li Liu (75607)

“…Meanwhile, 97 kinds of volatile metabolites were detected in these samples, most of which had a higher content in the fresh leaves. Moderate spreading is conducive to the release of the aroma of tea leaves, but fixation causes a sharp decrease in the content of most volatile metabolites. …”

Data_Sheet_2_Paternal Resistance Training Modulates Calcaneal Tendon Proteome in the Offspring Exposed to High-Fat Diet.xlsx by Ivo Vieira de Sousa Neto (8977685)

“…HF diet induced a decrease of abundance in tendon proteins related to extracellular matrix organization, transport, immune response and translation. …”

Image_2_Targeting the BMP Pathway in Prostate Cancer Induced Bone Disease.tif by Desiree M. Straign (8678604)

“…We next proceeded to test BMP inhibition in an injury model of established bone metastasis via intratibial injection of the MYC-CaP mouse prostate cell line into FVBN syngeneic mice. DMH1 treated mice had a modest decrease in trabecular bone and reduced lymphocytes in circulation without affecting tumor growth. …”

DataSheet_1_Arginine as the sole nitrogen source for Ostreococcus tauri growth: Insights on nitric oxide synthase enzyme.pdf by Noelia Foresi (8604351)

“…N starvation caused an inhibition of culture growth and a decrease in chlorophyll content. The addition of L-Arg to an N-deprived medium promotes a sustained growth rate of O. tauri culture and the increase of chlorophyll levels. …”

Data_Sheet_4_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…In addition, we addressed genetic relationships between local and global goat populations obtained from the AdaptMap project. Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Table_2_Human Chondrocyte Activation by Toxins From Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature.XLS by Isadora M. Villas-Boas (9394205)

“…In the supernatant of cell cultures treated with the extract, we observed increased IL-6, IL-8, MCP-1, prostaglandin E2, metalloproteinases (MMP-1, MMP-2, MMP-3 and MMP-13), and complement system components (C3, C4, and C5). We noticed a significant decrease in both aggrecan and type II collagen and an increase in HMGB1 protein in chondrocytes after extract treatment. …”

Table_1_Endothelial Barrier Integrity Is Disrupted In Vitro by Heme and by Serum From Sickle Cell Disease Patients.pdf by Vanessa Araujo Gomes Santaterra (9764693)

“…EB integrity was assessed by electric cell-substrate impedance sensing in the presence of varying concentrations of heme and sera from SCD patients or healthy volunteers. Heme caused a dose-dependent decrease of the electrical resistance of cell monolayers, consistent with EB disruption, which was confirmed by staining of junction protein VE-cadherin. …”

Progress towards lymphatic filariasis elimination in Ghana from 2000-2016: Analysis of microfilaria prevalence data from 430 communities by Nana Kwadwo Biritwum (7181408)

“…Repeated measurements were available for 78 communities, showing a steep decrease in mean mf prevalence in the first few years of MDA, followed by a gradual further decline. …”

Comparison of Age-Related Changes between GM-Volume, Cortical Thickness, Cortical Surface Area and Gyrification. by Daniel Klein (509727)

“…Blue colors indicate a significant decrease of lGI-, cortical thickness-, GM-volume- and cortical surface area- values with increasing age, whereas warmer colors are coded for age-related increases. …”

Table_1_The Influence of Fetch on the Holocene Thermal Structure of Hidden Lake, Glacier National Park.DOCX by Jeffery R. Stone (639225)

“…The basin of Hidden Lake is characterized by a complex morphometry; for example, three-dimensional modeling of the lake basin indicates that a decrease in lake level of 2 m would result in complete isolation of the deepest part of the lake basin from the rest of the lake. …”

Image_1_MaMYB4, an R2R3-MYB Repressor Transcription Factor, Negatively Regulates the Biosynthesis of Anthocyanin in Banana.JPEG by Gui-Ming Deng (4920463)

“…Consistent with the above results, metabolome results showed that there was a decrease in all three identified cyanidins and one delphinidin, the main anthocyanins that determine the color of banana leaves, whereas both transcriptome and reverse transcription–quantitative polymerase chain reaction analysis showed that many key anthocyanin synthesis structural genes and TF regulators were downregulated in MaMYB4 overexpressors. …”

Image4_Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions.JPEG by Marina Naval-Sanchez (6497258)

“…However, DNBSEQ-G400 data contained a significantly higher number of small, sub-nucleosomal reads (>30% increase) and a reduced number of bi-nucleosomal reads (>75% decrease), which resulted in narrower peak bases and improved peak calling, enabling the identification of 4% more differentially accessible regions between PSCs and fibroblasts. …”

Image_1_In vitro Fermentation Profile and Methane Production of Kikuyu Grass Harvested at Different Sward Heights.TIF by Alejandra Marín (10998987)

“…Herbage samples had similar contents of organic matter, neutral detergent fiber, and crude protein for all treatments. However, a higher acid detergent fiber (ADF) content in taller sward heights than in smaller sward heights and a tendency for metabolizable energy (ME) and IVOMD to decrease as sward height increased were found. …”

Table_1_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.XLSX by Tatiana E. Deniskova (5527175)

“…In addition, we addressed genetic relationships between local and global goat populations obtained from the AdaptMap project. Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Data_Sheet_1_Maternal Separation Combined With Limited Bedding Increases Anxiety-Like Behavior and Alters Hypothalamic-Pituitary-Adrenal Axis Function of Male BALB/cJ Mice.XLSX by Rodrigo Orso (7320533)

“…We observed that ELS dams presented altered quality of maternal care, characterized by a decrease in arched-back nursing, and an increase in passive nursing. …”

Table3_Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions.XLSX by Marina Naval-Sanchez (6497258)

“…However, DNBSEQ-G400 data contained a significantly higher number of small, sub-nucleosomal reads (>30% increase) and a reduced number of bi-nucleosomal reads (>75% decrease), which resulted in narrower peak bases and improved peak calling, enabling the identification of 4% more differentially accessible regions between PSCs and fibroblasts. …”

Image_1_Paternal Resistance Training Modulates Calcaneal Tendon Proteome in the Offspring Exposed to High-Fat Diet.tif by Ivo Vieira de Sousa Neto (8977685)

“…HF diet induced a decrease of abundance in tendon proteins related to extracellular matrix organization, transport, immune response and translation. …”

Image4_Disordered Gut Microbiota in Colorectal Tumor-Bearing Mice Altered Serum Metabolome Related to Fufangchangtai.TIF by Mengmeng Cai (12480588)

“…</p><p>Results: The tumor volume of mice showed no significant decrease after FFCT intervention. The levels of CD4⁺ and CD8⁺T lymphocytes showed a significant increase under the intervention of FFCT. …”