Image_2_Secular trends and features of thalamic hemorrhages compared with other hypertensive intracerebral hemorrhages: an 18-year single-center retrospective assessment.pdf by Hiroyuki Katano (16830573)

“…</p>Discussion<p>Our findings revealed an increasing trend for thalamic hypertensive hemorrhage and a decreasing trend for putaminal hemorrhage. The thalamic hemorrhage increase was observed in both young and older patients, regardless of gender. …”

Image6_Disordered Gut Microbiota in Colorectal Tumor-Bearing Mice Altered Serum Metabolome Related to Fufangchangtai.TIF by Mengmeng Cai (12480588)

“…</p><p>Results: The tumor volume of mice showed no significant decrease after FFCT intervention. The levels of CD4⁺ and CD8⁺T lymphocytes showed a significant increase under the intervention of FFCT. …”

Data Sheet 1_Epidemiological trends and age-period-cohort effects on subarachnoid hemorrhage burden across the BRICS-plus from 1992 to 2021.docx by Liang Guo (95092)

“…Background<p>Subarachnoid hemorrhage (SAH) is a major global health concern associated with disproportionately high morbidity and mortality. …”

Image3_Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions.JPEG by Marina Naval-Sanchez (6497258)

“…However, DNBSEQ-G400 data contained a significantly higher number of small, sub-nucleosomal reads (>30% increase) and a reduced number of bi-nucleosomal reads (>75% decrease), which resulted in narrower peak bases and improved peak calling, enabling the identification of 4% more differentially accessible regions between PSCs and fibroblasts. …”

Introduction of Application of Gini Coefficient to Heart Rate Variability Spectrum for Mental Stress Evaluation by Miguel Enrique Sánchez-Hechavarría (7368665)

“…All the differences were considered statistically significant for p < 0.05. Results: There was a significant decrease in HF power (p = 0.046), as well as significant increases in heart rate (p = 0.004), LF power (p = 0.033), LF2 power (p = 0.019) and LF/HF (p = 0.002) during mental stress. …”

Image_4_YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response.tif by Robin Caire (11816078)

“…Inhibiting YAP/TAZ transcriptional activity with VP restored a common phenotype in RA FLS with a decrease in apoptosis resistance, proliferation, invasion, and inflammatory response. …”

Image_2_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.tif by Li Liu (75607)

“…Meanwhile, 97 kinds of volatile metabolites were detected in these samples, most of which had a higher content in the fresh leaves. Moderate spreading is conducive to the release of the aroma of tea leaves, but fixation causes a sharp decrease in the content of most volatile metabolites. …”

Table_3_Altered Transcription Factor Expression Responses to Exercise in Insulin Resistance.XLSX by Rocio Zapata-Bustos (10533320)

“…Q-rt-PCR analysis of RNA and immunoblot analysis from pre- and post-exercise muscle biopsies revealed several transcription and growth factors that had altered responses to exercise in insulin resistant participants. A significant increase (EGR3 and CTGF) and decrease (RELA and ATF2) in the mRNA expression of transcription and growth factors was found after exercise in the lean group, but not in the obese participants.…”

Data Sheet 1_Impact of straw return on greenhouse gas emissions from maize fields in China: meta-analysis.docx by Qi Sun (127)

“…With a nitrogen rate increase, N₂O emission effects under straw return initially increased and then decreased. …”

Table_2_MaMYB4, an R2R3-MYB Repressor Transcription Factor, Negatively Regulates the Biosynthesis of Anthocyanin in Banana.XLSX by Gui-Ming Deng (4920463)

“…Consistent with the above results, metabolome results showed that there was a decrease in all three identified cyanidins and one delphinidin, the main anthocyanins that determine the color of banana leaves, whereas both transcriptome and reverse transcription–quantitative polymerase chain reaction analysis showed that many key anthocyanin synthesis structural genes and TF regulators were downregulated in MaMYB4 overexpressors. …”

Table_2_Female Rats Are Resistant to Cognitive, Motor and Dopaminergic Deficits in the Reserpine-Induced Progressive Model of Parkinson’s Disease.DOCX by Alvaro C. Lima (11601898)

“…Our findings show that females present a delay and/or a prevention in the reserpine-induced motor alterations in the progressive PD model, compatible with the lower prevalence of this disease in women. …”

Image_2_Porphyromonas gingivalis Induces Increases in Branched-Chain Amino Acid Levels and Exacerbates Liver Injury Through livh/livk.tif by Leng Wu (5190419)

“…Additionally, livh deletion had no effect on bacterial growth, EPS production, invasion efficiency, and in vivo colonization, whereas the Δlivk strain showed a slight decrease in invasion efficiency and in vivo colonization. …”

Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters synaptic structural matching, and exaggerates protein synthesis by Asma Soltani (4356841)

“…By means of RT-qPCR, we confirmed that En1 and En2 were expressed at low levels in hippocampus and hippocampal neurons, and observed a pronounced decrease in En2 expression at birth and during the first postnatal week, a period characterized by intense synaptogenesis. …”

Non-Participation during Azithromycin Mass Treatment for Trachoma in The Gambia: Heterogeneity and Risk Factors by Tansy Edwards (122527)

“…<div><p>Background</p><p>There is concern that untreated individuals in mass drug administration (MDA) programs for neglected tropical diseases can reduce the impact of elimination efforts by maintaining a source of transmission and re-infection.</p><p>Methodology/Principal Findings</p><p>Treatment receipt was recorded against the community census during three MDAs with azithromycin for trachoma in The Gambia, a hypo-endemic setting. …”

Nilotinib inhibits cell viability and neurosphere formation in medulloblastoma cells (MB-PDX and DAOY). by Kirti Kandhwal Chahal (7411091)

“…Nilotinib was observed to be most potent in inhibiting the formation of NS from single cells. (<b>f)</b> A representative Western blot for quantitation of nuclear Gli-1 in MB-PDX and DAOY cells shows a decrease in Gli-1 protein after treatment with 5 μM Nilotinib for 24 hours. …”

DataSheet2_Soil Fertility Changes With Climate and Island Age in Galápagos: New Baseline Data for Sustainable Agricultural Management.PDF by Matthias Strahlhofer (11801174)

“…Mehlich (III)-extractable base cations Ca, K, Mg and Na as well as P, Fe and Zn showed a decreasing tendency from the youngest to the oldest island, while Mn increased with island age. …”

DataSheet1_Cationic lipid-assisted nanoparticles for simultaneous delivery of CD47 siRNA and R848 to promote antitumor immune responses.docx by Simin Li (314006)

“…Mechanistically, downregulation of CD47 expression and activation of DCs took part in promoting the immune response of cytotoxic T cells (CTLs). Meanwhile, a decrease of myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) indicated the modulating of the tumor immune microenvironment.…”

Redox Balance in <i>Lactobacillus reuteri</i> DSM20016: Roles of Iron-Dependent Alcohol Dehydrogenases in Glucose/ Glycerol Metabolism by Lu Chen (75170)

“…<div><p><i>Lactobacillus reuteri</i>, a heterofermentative bacterium, metabolizes glycerol via a Pdu (propanediol-utilization) pathway involving dehydration to 3-hydroxypropionaldehyde (3-HPA) followed by reduction to 1,3-propandiol (1,3-PDO) with concomitant generation of an oxidized cofactor, NAD⁺ that is utilized to maintain cofactor balance required for glucose metabolism and even for oxidation of 3-HPA by a Pdu oxidative branch to 3-hydroxypropionic acid (3-HP). …”

Data_Sheet_6_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…In addition, we addressed genetic relationships between local and global goat populations obtained from the AdaptMap project. Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

DataSheet1_Evaluation of the Hypoglycemic Activity of Morchella conica by Targeting Protein Tyrosine Phosphatase 1B.PDF by Naeema Begum (10801401)

“…In vivo investigation showed a gradual decrease in blood sugar level in M. conica-treated mice (132 mg/dl) at a concentration of 100 mg/kg as compared to diabetic mice (346 mg/dl). …”