Inhibiting the mu opioid receptor (MOR), Src, Gab-1, PI3 kinase or STAT3 attenuates opioid and growth factor-induced epithelial mesenchymal transition (EMT) in human lung cancer ce... by Frances E. Lennon (541593)

“…A decrease in claudin-1 expression is suggestive of an epithelial mesenchymal transition.…”

Image_1_The Impact of Hippocampal Sex Hormones Receptors in Modulation of Depressive-Like Behavior Following Chronic Anabolic Androgenic Steroids and Exercise Protocols in Rats.TIF by Dragica Selakovic (4068406)

“…<p>The aim of this study was to evaluate alterations in depressive-like behaviors in rats following chronic administration of a supraphysiological dose of anabolic androgenic steroids (AASs) as well as exposure to a prolonged exercise protocol. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Intermediate metabolites produced by <i>S</i>. <i>aureus</i> are sensed and utilized as carbon sources by <i>P</i>. <i>aeruginosa</i>. by Tiffany M. Zarrella (12902741)

“…<p><b>(A)</b> Transposon library screen with P′<i>acoR</i>-reporter strain to determine mutations in <i>S</i>. …”

Image_1_Lower High-Density Lipoproteins Levels During Human Immunodeficiency Virus Type 1 Infection Are Associated With Increased Inflammatory Markers and Disease Progression.jpeg by Damariz Marín-Palma (5392466)

“…</p>Results<p>HIV-1-infected individuals showed a significant decrease in HDL levels, particularly those subjects with higher viral load and lower CD4+ T-cell counts. …”

“Unburdened–Student edition” content. by Mary Beth Spitznagel (14537189)

“…Unburdened will be adapted for student use in a self-guided digital format and embedded into 5 veterinary medical or technology programs. …”

Presentation_1_Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Re... by Jo-Fan Chang (6237680)

“…In conclusion, the data suggest that sildenafil and vardenafil induce PDE5-independent apoptotic sensitization to doxorubicin (or other topoisomerase II inhibitors) through impairment of both HR and NHEJ repair systems that are evident by a decrease of nuclear Rad51 levels and their foci formation in the nucleus, and an inhibition of Ku80 DNA end-binding capability. …”

Table_1_MicroRNA-483-5p Predicts Poor Prognosis and Promotes Cancer Metastasis by Targeting EGR3 in Nasopharyngeal Carcinoma.docx by Xi-Zhao Li (5090681)

“…Besides, a significant decrease of EGR3 expression was found in fresh biopsy tissues from NPC patients, in contrast to miR-483-5p expression. …”

Insulin sensitizer effects in wild type and knockdown flies. by Jerry R. Colca (409220)

“…<p>(<b>A</b>) Acute insulin action was measured in inverted larvae in the absence (−) or presence (+) of 2 µM recombinant insulin. …”

<em>Arabidopsis</em> COMPASS-Like Complexes Mediate Histone H3 Lysine-4 Trimethylation to Control Floral Transition and Plant Development by Danhua Jiang (197054)

“…Loss of function of <em><u>A</u>RABIDOPSIS</em> A<u>sh2 R</u>ELATIVE (ASH2R) causes a great decrease in genome-wide H3K4 trimethylation, but not in di- or mono-methylation. …”

Neutral Ligands for Selective Chloride Anion Complexation:  (α,α,α,α)-5,10,15,20-Tetrakis(2-(arylurea)phenyl)porphyrins by Raymond C. Jagessar (3005310)

“…On the other hand, the corresponding metalloporphyrins exhibited a decrease in binding strength and selectivity in DMSO-<i>d</i>₆. …”

Table 2_Effect of dietary supplementation with Brevibacillus laterosporus on broiler growth performance, meat quality and gut microbiome.xlsx by Haixia Han (336363)

“…Specifically, the HBL group exhibited a notable increase in muscle C18:3n3 content, and a significant decrease in muscle C18:1n9t and C20:3n3 content. …”

Localisation and quantification of NL2 immunoreactivity within the hippocampus of WT and dystrophin-deficient mice, reacted and imaged under identical conditions. by Elżbieta Krasowska (635317)

“…<p>(A 1) shows the stereotypical pattern of NL2 immunoreactivity within the CA1 region of tissue from WT animals. …”

Table1_Genetic interactions of schizophrenia using gene-based statistical epistasis exclusively identify nervous system-related pathways and key hub genes.XLSX by Sathish Periyasamy (478304)

“…There were ∼9.5 million GIs with a p-value ≤ 1 × 10⁻⁵. Approximately 4.8 million GIs showed an increased risk (OR > 1.0), while ∼4.75 million GIs had a decreased risk (OR <1.0) for schizophrenia.…”

DataSheet1_Gas Bubble Dynamics During Methane Hydrate Formation and its Influence on Geophysical Properties of Sediment Using High-Resolution Synchrotron Imaging and Rock Physics M... by B. N. Madhusudhan (12833870)

“…<p>Gas bubble in aquatic sediments has a significant effect on its geophysical and geomechanical properties. …”

Image3_Computational analysis of cancer cell adhesion in curved vessels affected by wall shear stress for prediction of metastatic spreading.TIFF by Nahid Rahmati (18618076)

“…Quantitative analysis shows a 25% decrease in the wall shear stress in low-shear regions and a 58.5% increase in the high-shear region. …”

DataSheet6_Transcriptional time course after rotator cuff repair in 6 month old female rabbits.XLSX by Laura S. Vasquez-Bolanos (11242737)

“…Many were also significantly enriched at 2 weeks, with the addition of NIF/NF-kappaB signaling, transcription in response to hypoxia, and mRNA stability alongside many additional pathways. There was also a shift in transcriptional activity at 4 weeks post-repair with significantly enriched pathways for lipids, hormones, apoptosis, and cytokine activity, despite an overall decrease in the number of differentially expressed genes. …”

Image1_Genetic interactions of schizophrenia using gene-based statistical epistasis exclusively identify nervous system-related pathways and key hub genes.pdf by Sathish Periyasamy (478304)

“…There were ∼9.5 million GIs with a p-value ≤ 1 × 10⁻⁵. Approximately 4.8 million GIs showed an increased risk (OR > 1.0), while ∼4.75 million GIs had a decreased risk (OR <1.0) for schizophrenia.…”

Image_2_C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune En... by Zhi-Yuan Shen (10431413)

“…<p>Experimental autoimmune encephalomyelitis (EAE) is a classical murine model for Multiple Sclerosis (MS), a human autoimmune disease characterized by Th1 and Th17 responses. …”

Data_Sheet_1_The 1-aminocyclopropane-1-carboxylic acid deaminase-producing Streptomyces violaceoruber UAE1 can provide protection from sudden decline syndrome on date palm.pdf by Khawla J. Alwahshi (13158522)

“…Thus, the number of conidia of Fs recovered from plants pre-treated with both BCAs was comparable, but significantly (P < 0.05) reduced compared to plants without any BCA treatment. In addition, a significant (P < 0.05) decrease in ACC levels of both the root and shoot tissues was detected inSv + Fs seedlings to almost similar levels of healthy seedlings. …”