Table 1_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Data_Sheet_2_Community-based treatment of cutaneous leishmaniasis using cryotherapy and miltefosine in Southwest Ethiopia: the way forward?.docx by Saskia van Henten (7474520)

“…Background<p>Cutaneous leishmaniasis (CL) is a common, yet massively underreported skin morbidity in Ethiopia. …”

Table_2_Alterations of the gut virome in patients with systemic lupus erythematosus.xlsx by Changming Chen (275732)

“…</p>Results<p>SLE patients exhibited a significant decrease in gut viral diversity in the bulk metagenome dataset, but this change was not significant in the VLP metagenome dataset. …”

Image 2_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Table_5_Resveratrol Mediates the Apoptosis of Triple Negative Breast Cancer Cells by Reducing POLD1 Expression.xlsx by Zhi-Jie Liang (9157439)

“…<p>Resveratrol (RSV) is known to possess anticancer properties in many types of cancers like breast cancer, in which POLD1 may serve as a potential target. However, the anticancer mechanism of RSV on triple negative breast cancer (TNBC) remains unclear. …”

Homeostasis at PN::KC synapses of aged flies. by Varun K. Gupta (3185298)

“…<p>(a–c) Mushroom body calyx of 3d and 30d mb247::Dα7^GFP flies and 30d^Spd mb247:: Dα7^GFP flies immunostained for GFP-labeled Dα7 as well as BRP (corresponding single z-planes are shown). …”

Image1_MiR-208b Regulates the Conversion of Skeletal Muscle Fiber Types by Inhibiting Mettl8 Expression.TIF by Xiang Li (114679)

“…In a previous study, our lab has demonstrated that there is a decrease in type I muscle fibers and an increase in type IIB muscle fibers in skeletal muscle of myostatin gene-edited Meishan pigs. …”

Table_2_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.XLSX by Alessia Buso (6653861)

“…Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. …”

Table_2_Fecal microbial and metabolic characteristics of swine from birth to market.CSV by Huan He (548057)

“…The correlation between fecal metabolites and microbiota revealed that the microbes with an increasing trend were positively correlated with the metabolites affecting the tryptophan metabolic pathway from the overall trend, while the microbes with a decreasing trend were opposite. In addition, the microbes with an increasing trend were negatively correlated with the metabolites affecting the lysine pathway.…”

Image_10_Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms.tif by Liu Liu (512237)

“…The mechanism of S1P receptor agonists in treating psoriasis might be related to a decrease in the number of white blood cells, topical lymph node weight, interleukin-23 mRNA levels, and percentage of CD3⁺ T cells (p<0.05). …”

Drainage in Gilgel Gibe catchment. by Zewde Alemayehu Tilahun (16462668)

“…The projected climate change shows a decrease in surface runoff, groundwater, and water yield, resulting in an overall decline of annual flow. …”

DataSheet_1_Impact of intrafraction motion in pancreatic cancer treatments with MR-guided adaptive radiation therapy.docx by Doris N. Rusu (17624388)

“…Compared to the scheduled plan, the post-treatment plans showed a decrease in the V33Gy, demonstrating the benefit of plan adaptation for 66% of the fractions for the duodenum, 95% for the stomach, 100% for the colon, and 79% for the small bowel.…”

Tandem Imaging of Breath Ethanol and Acetaldehyde Based on Multiwavelength Enzymatic Biofluorometry by Kenta Iitani (4175995)

“…Reduction of AcH by ADH_RD consumed NADH, leading to a decrease in blue fluorescence (ex. 340 nm, fl. 490 nm). …”

Table_1_Compensatory brain activity pattern is not present in older adults during the n-back task performance—Findings based on EEG frequency analysis.DOC by Ludmiła Zając-Lamparska (8056364)

“…At the same time, at this difficulty level, cognitive performance was worse in older adults than in young adults, which could reduce the chances of observing compensatory brain activity. The significant decrease in theta power observed in both age groups with rising task difficulty can reflect a declining capacity for efficient cognitive functioning under increasing demands rather than adapting to this increase. …”

Table 1_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Myo1b kd reduces the number of SIT1 transporters at the apical plasma membrane. by Shigeru Komaba (794148)

“…<p>OK cells were transfected with SIT1-V5 and either collectrin or empty vector (pLenti-CMV Hygro) and stained with rhodamine phalloidin to visualize the apical microvilli. A, Immunoblot showing that Myo1b kd increased SIT1-V5 expression. …”

Table_1_Characterization and potential lipid-lowering effects of lactic acid bacteria isolated from cats.DOCX by Shukun Liang (18433158)

“…These three strains exhibited robust growth and adherence to epithelial cells, along with adaptability to low pH (greater than 70%) and high bile salt conditions (greater than 60%), and remarkable cholesterol degradation and anti-pathogen activity. Sixteen mice were fed a high-fat diet (HFD) from 4 to 8 weeks of age, while a control group of the same size received a normal diet (ND). …”

Image_5_NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes.jpeg by Kathryn W. Juchem (11940605)

“…We found that although NFAM1 deletion had no impact on development of gut pathology, we did observe a decrease in serum TNF-α, confirming that NFAM1 promotes pro-inflammatory cytokine production in vivo. …”

Image_3_Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics.tif by Prabal Subedi (1946704)

“…Radiotherapy (RT) is used to treat the majority of these patients. A common side-effect of RT is the onset of oral mucositis, which decreases the quality of life and represents the major dose-limiting factor in RT. …”

Seeking Dual Channels for Conducting in Color Paradise: Optimizing Electron Hopping and Ion Diffusion in Polyimides Films to Contribute Better Performance of Electrochromic Devices by Minghao Zhai (14444674)

“…However, obtaining EC polymer materials with more stability and faster response times is still a great challenge. Based on the concept that a planar block will improve the electron transfer and a nonplanar block will decrease the dense packing, the special combination will encourage improvement of conductivity of ion and electron simultaneously. …”