Functional and Molecular Effects of Arginine Butyrate and Prednisone on Muscle and Heart in the <em>mdx</em> Mouse Model of Duchenne Muscular Dystrophy by Alfredo D. Guerron (247057)

“…</p><h3>Methodology/Principal Findings</h3><p>In this study, we have treated <em>mdx</em> mice with arginine butyrate, prednisone, or a combination of arginine butyrate and prednisone for 6 months, beginning at 3 months of age, and have comprehensively evaluated the functional, biochemical, histological, and molecular effects of the treatments in this DMD model. …”

Table 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx by Yiwen Li (354034)

“…PI3K signaling pathway was identified as a central mediator of the microbiota interaction in DMIRI. …”

Supplementary Material for: Basophil CD203c Levels Are Increased at Baseline and Can Be Used to Monitor Omalizumab Treatment in Subjects with Nut Allergy by Gernez Y. (3849832)

Data_Sheet_1_Estrogen Mediates an Atherosclerotic-Protective Action via Estrogen Receptor Alpha/SREBP-1 Signaling.DOCX by Fei Xie (437662)

“…E2 might enhance the cellular sensitivity of statins and could be used as a novel therapeutic strategy against atherosclerotic disorders in postmenopausal women.…”

Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E₂ alterations in <i>Caenorhabditis elegans</i> under extremely low-frequency electr... by Yongyan Sun (5847446)

“…</p> <p><b>Results:</b> The TCA cycle enzyme, fumarase was found with decreased expression under ELF-EMF exposure. And arachidonic acid (ArA) and prostaglandin E₂(PGE₂) showed elevated concentrations, with increased expression of prostaglandin E₂ synthase (PGES-2) in ELF-EMF exposed worms. …”

Image_1_Colonization of Raphanus sativus by human pathogenic microorganisms.TIF by Sonia Szymańska (3823558)

“…The results suggest that E. coli and L. monocytogenes show a higher ability to colonize and move across the plant than B. cereus and S. enterica. …”

Image_1_Insights Into the MYB-Related Transcription Factors Involved in Regulating Floral Aroma Synthesis in Sweet Osmanthus.JPEG by Xin Yan (17064)

“…In this study, we conducted a genome-wide analysis of MYB-related proteins in sweet osmanthus; 212 OfMYB-related TFs were divided into three distinct subgroups based on the phylogenetic analysis. …”

Evaluation of retinal and choroidal microvascular changes in patients who received hydroxychloroquine by optical coherence tomography angiography by Esat Cinar (10366844)

“…The high-and low-risk groups consisted of patients receiving hydroxychloroquine for ≥5 years (14 eyes of 28 patients) and <5 years (14 eyes of 28 patients), respectively. A total of 28 age- and gender-matched volunteers were enrolled as the control group. …”

Effects of High-Dose Genistein on the Hypothalamic RNA Profile and Intestinal Health of Female Chicks by Zengpeng Lv (4237459)

“…Chicks exposed to high-dose genistein by intraperitoneal injection (416 ± 21, 34.5 ± 2.5) and feed supplementation (308 ± 19, 27.2 ± 2.1) both showed a reduced body weight gain and feed intake in comparison with the control group (261 ± 16, 22.7 ± 1.6, <i>P</i> < 0.01). …”

Data_Sheet_2_Peroxisome Proliferator-Activated Receptor α Activation Protects Retinal Ganglion Cells in Ischemia-Reperfusion Retinas.DOCX by Fei Yao (43685)

“…However, the mechanism related to retinal IR is controversial, and a drug that could prevent the RGC loss caused by IR is still lacking. …”

Longitudinal association between dietary protein intake and survival in peritoneal dialysis patients by Shu-Hong Bi (13172031)

“…<p>Decreased dietary protein intake (DPI) may lead to protein-energy malnutrition and may be associated with increased mortality risk. …”

Image_3_Wheat F-box Protein TaFBA1 Positively Regulates Plant Drought Tolerance but Negatively Regulates Stomatal Closure.tif by Jie An (543888)

“…In addition, TaFBA1 was found to be a negative regulator of ABA-induced stoma movement; mRNA transcription of certain ABA signaling-related genes was lower in TaFBA1 OE plants than in WT plants following ABA treatment. …”

DataSheet_1_Global burden of major gastrointestinal cancers and its association with socioeconomics, 1990–2019.pdf by Mei-Zhu Hong (518188)

“…</p>Conclusion<p>There is a profound association between socioeconomics and burden of common cancers of the gastrointestinal tract. …”

Table_2_Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson’s Disease.pdf by Wiebke Hermann (9214145)

“…Despite the fact that sleep disturbances are a major issue in PD patients, only limited data are available regarding interactions of sleep disturbances and cognitive performance.…”

Image_1_PTEN Inhibition Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury Through PTEN/E2F1/β-Catenin Pathway.jpeg by Dan Zhao (285025)

“…<p>Intracerebral hemorrhage (ICH) is a subtype of stroke with highest mortality and morbidity. …”

Table 1_Gut-tropic α4β7+CD8+ T cells contribute to pancreatic β cell destruction in type 1 diabetes.docx by Zhangyao Su (5980565)

“…Gut-tropic CD8⁺ T cells showed augmented cytokine production and cytotoxicity against islet cells. Integrin α4β7 was a key mediator of the pathogenicity of CD8⁺ T cells and upregulated by the inflammatory signals. …”

Data_Sheet_1_Metabolomics combined with intestinal microbiota reveals the mechanism of compound Qilian tablets against diabetic retinopathy.PDF by Jiangwei Jia (19431646)

“…Compound Qilian tablets (CQLT) is a traditional Chinese medicine (TCM) developed for treating DR, but its mechanism is still unclear. …”

Dipeptide makeup of ancient proteins. by Gustavo Caetano-Anollés (65405)

“…<p>A. The distribution of dipeptide compositions in proteins shows remarkable conservation along the FF timeline. …”

Data Sheet 2_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind... by Yanping Wang (275956)

“…</p>Methods<p>In this study, the chronic unpredictable mild stress (CUMS) method was used to establish a rat model of depression to investigate the ameliorative effects of HLTP on depression.…”

Schematic summary: MC immuno-phenotype and MC-CD8+ T-cell interactions in healthy compared to lesional AA skin. by Marta Bertolini (564966)

“…Most of them express IL-10, TGFβ1 while only some express OX40L and PD-L1 and very few express CD30L and ICAM-1 (A). In lesional AA skin, the degranulation of MCs is increased (release of tryptase, heparin and histamine) and the expression of tryptase is increased, while the contents of TGFbeta1, IL-10 are decreased. …”