Image1_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.TIFF by Haomiao Li (2743693)

“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”

Image_2_EP3 Blockade Adds to the Effect of TP Deficiency in Alleviating Endothelial Dysfunction in Atherosclerotic Mouse Aortas.JPEG by Chuangjia Hu (7433447)

“…EP3 antagonism not only increased the above relaxation, but also reversed the contractile response evoked by acetylcholine in NO synthase-inhibited atherosclerotic ApoE^–/–/TP^–/– rings into a relaxation sensitive to I prostanoid receptor antagonism. …”

Data file. by Md. Utba Rashid (10700694)

“…The average physical domain score decreased significantly from baseline to follow-up, whereas a significant increase in average scores has been observed in other domains at the follow-up (p<0.05). …”

DataSheet4_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”

Table1_Oxidative balance score reflects vascular endothelial function of Chinese community dwellers.DOCX by Jianhua Liu (33232)

“…<p>Background: The oxidative balance score (OBS) is a composite estimate of the overall pro- and antioxidant risk status in an individual. …”

Image1_Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway.tif by Qin Ru (11623021)

“…The combination of network pharmacology approaches with experimental validation may offer a useful tool to characterize the molecular mechanism of multicomponent complexes.…”

Data Sheet 1_Longitudinal analysis of usage and public awareness of tyrosine kinase inhibitors for CML.docx by Adrian E. Schroer (17937971)

“…</p>Discussion<p>These data highlight a shift toward newer TKIs in CML treatment, mirroring guideline recommendations and rising public awareness. …”

Table_1_Wheat F-box Protein TaFBA1 Positively Regulates Plant Drought Tolerance but Negatively Regulates Stomatal Closure.doc by Jie An (543888)

“…In addition, TaFBA1 was found to be a negative regulator of ABA-induced stoma movement; mRNA transcription of certain ABA signaling-related genes was lower in TaFBA1 OE plants than in WT plants following ABA treatment. …”

DataSheet1_Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice.docx by Lu Xia (1509745)

“…</p><p>Conclusion: GSDMD-mediated pyroptosis is involved in the mechanism of kainic acid-induced seizures. Our study provides a new potential therapeutic target for seizure control.…”

White Adipose Tissue Resilience to Insulin Deprivation and Replacement by Lilas Hadji (623766)

“…The results show that insulin is a major determinant of bimodal cell repartition in adipose tissues.…”

Image 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Neonatal ODA supplementation may offer a promising intervention to mitigate the cognitive deficits and brain changes induced by MSI during lactation.…”

Supplementary Material for: MiR-506-3p Promotes the Proliferation and Migration of Vascular Smooth Muscle Cells via Targeting KLF4 by Dong H. (4121092)

“…Additionally, KLF4 was confirmed as a target gene of miR-506-3p and could be negatively regulated by miR-506-3p. …”

Data_Sheet_4_ZmPP2C26 Alternative Splicing Variants Negatively Regulate Drought Tolerance in Maize.XLSX by Fengzhong Lu (12373204)

“…In this study, we characterized a clade B member of maize PP2C family, i.e., ZmPP2C26, that negatively regulated drought tolerance by dephosphorylating ZmMAPK3 and ZmMAPK7 in maize. …”

Image_5_B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis.tif by Christopher Tay (335988)

“…These findings suggest that targeting B cell and CD4 T cell interaction may be a therapeutic strategy to limit atherosclerosis progression.…”

<i>S. boulardii</i> Fails to Hold Its Cell Wall Integrity against Nonpathogenic <i>E. coli</i>: Are Probiotic Yeasts Losing the Battle? by Satyajit Lenka (10290092)

“…Co-cultured methylene blue-supplemented agar-plate assay indicates that rough lipopolysaccharides might be playing a key role in <i>S. boulardii</i> cell wall damage. …”

Data_Sheet_1_Retrosplenial Cortex Effects Contextual Fear Formation Relying on Dysgranular Constituent in Rats.docx by Ting-Ting Pan (11589964)

“…In addition to the well-recognized hippocampal–amygdalar system, the retrosplenial cortex (RSC) is getting more and more attention due to substantial involvement in CFC, but with a poor understanding of the specific roles of its two major constituents—dysgranular (RSCd) and granular (RSCg). …”

Image1_Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.TIF by Myung-Eui Seo (6822518)

“…</p><p>Discussion: Therefore, we propose a methodology that combines in silico prediction algorithms and functional assays on polymorphic CYPs with multiple substrates to evaluate the changes in the metabolism of all possible genomic variants in CYP genes. …”

Raw data of indirect ELISAs shown in S5 Fig. by Inga Petersen (9253821)

“…Here, we investigated whether a negatively charged peptide tail fused to the αSyn aggregate-specific antibodies SynO2 and 9E4 could enhance the antibodies’ avidity to αSyn aggregates in order to improve their potential therapeutic effect through inhibiting cell-to-cell spreading and enhancing the clearance of extracellular aggregates. …”

DataSheet7_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”

Table_1_Identification of subclusters and prognostic genes based on glycolysis/gluconeogenesis in hepatocellular carcinoma.docx by Dan Chen (32468)

“…The study also identified five intersecting DEGs from candidate genes in TCGA, GSE14520, and GSE141198 as prognostic genes, which had a protective role in HCC patient prognosis. Compared with the control group, the prognostic genes all showed decreased expression in HCC patients in RT-qPCR and Western blot analyses. …”