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27201
Data_Sheet_1_Transcript Isoforms of SLC7A11-AS1 Are Associated With Varicocele-Related Male Infertility.docx
Published 2020“…Overexpression of SLC7A11-AS1 isoform 6 in NT2 and NCCIT cell lines resulted in a significant downregulation of SLC7A11 gene expression, which consequently decreased GSH levels and concomitantly increased ROS levels and enhanced lipid peroxidation, which jeopardized cell survival and promoted cell death. …”
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27202
Image_3_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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27203
Data_Sheet_2_Transcript Isoforms of SLC7A11-AS1 Are Associated With Varicocele-Related Male Infertility.zip
Published 2020“…Overexpression of SLC7A11-AS1 isoform 6 in NT2 and NCCIT cell lines resulted in a significant downregulation of SLC7A11 gene expression, which consequently decreased GSH levels and concomitantly increased ROS levels and enhanced lipid peroxidation, which jeopardized cell survival and promoted cell death. …”
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27204
Image_2_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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27205
DataSheet_1_Dectin-1-Mediated Production of Pro-Inflammatory Cytokines Induced by Yeast β-Glucans in Bovine Monocytes.pdf
Published 2021“…Production of IL-8 and TNF expression decreased significantly after CLEC7A knockdown using two different pairs of siRNAs. …”
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27206
Table_4_FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis.docx
Published 2022“…Total antioxidant capacity (T-AOC) were markedly decreased and positively associated with FOXO3a in AS. …”
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27207
A potential new approach for treating systemic sclerosis: Dedifferentiation of SSc fibroblasts and change in the microenvironment by blocking store-operated Ca<sup>2+</sup> entry
Published 2019“…However, our study revealed three levels of TGF-β1 expression in SSc patients, indicating that inhibiting TGF-β is not sufficient to treat SSc. A previous clinical trial also displayed disappointing results. …”
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27208
image_1.tif
Published 2018“…Formulation of DNA and two agonists into the DDA liposome decreased zeta potential but increased the stability of storage, which resulted in a slower and longer-lasting release of DNA from the DNA–DMT complex than the DNA–DDA liposome. …”
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27209
Image_2_Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A.TIF
Published 2020“…Increasing the dose of GLA-SE from 2.5 to 5 μg in pre-exposed volunteers improved anti-P27A affinity and decreased the number of recognized epitopes. …”
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27210
Proteomic Profiling in <i>Drosophila</i> Reveals Potential Dube3a Regulation of the Actin Cytoskeleton and Neuronal Homeostasis
Published 2013“…<div><p>The molecular defects associated with Angelman syndrome (AS) and 15q duplication autism are directly correlated to expression levels of the E3 ubiquitin ligase protein UBE3A. Here we used <i>Drosophila melanogaster</i> to screen for the targets of this ubiquitin ligase under conditions of both decreased (as in AS) or increased (as in dup(15)) levels of the fly Dube3a or human UBE3A proteins. …”
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27211
Table_2_FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis.docx
Published 2022“…Total antioxidant capacity (T-AOC) were markedly decreased and positively associated with FOXO3a in AS. …”
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27212
Evolved <i>efgA</i> alleles have a variety of predicted folding and binding stabilities.
Published 2021“…<p>We used our MD+FoldX approach [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001208#pbio.3001208.ref079" target="_blank">79</a>] to predict the effect of all possible 19 mutations at each amino acid site on monomers or tetramer formation. …”
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27213
Table_1_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.DOCX
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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27214
Table_6_FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis.docx
Published 2022“…Total antioxidant capacity (T-AOC) were markedly decreased and positively associated with FOXO3a in AS. …”
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27215
image_2.tif
Published 2018“…Formulation of DNA and two agonists into the DDA liposome decreased zeta potential but increased the stability of storage, which resulted in a slower and longer-lasting release of DNA from the DNA–DMT complex than the DNA–DDA liposome. …”
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27216
DataSheet_1_METTL3-Mediated N6-Methyladenosine Modification of Trim59 mRNA Protects Against Sepsis-Induced Acute Respiratory Distress Syndrome.docx
Published 2022“…Here, we show that the levels of m<sup>6</sup>A RNA were significantly decreased in septic lungs and that METTL3 was the main regulator involved in the absence of m<sup>6</sup>A RNA modification. …”
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27217
Table_3_Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment.xlsx
Published 2022“…In support of this, we found decreased MDSC numbers, and increased numbers of CD4<sup>+</sup> T cells and natural killer T (NK-T) cells in lungs from cancer-bearing mice treated with S100A8. …”
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27218
Image_5_Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment.tif
Published 2022“…In support of this, we found decreased MDSC numbers, and increased numbers of CD4<sup>+</sup> T cells and natural killer T (NK-T) cells in lungs from cancer-bearing mice treated with S100A8. …”
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27219
Table_1_CRISPR interference for sequence-specific regulation of fibroblast growth factor receptor A in Schistosoma mansoni.xlsx
Published 2023“…We showed that SmfgfrA repression resulted in considerable phenotypic differences in the modulated parasites compared with controls, including reduced levels of SmfgfrA transcription and decreased protein expression of SmFGFRA, a decline in EdU (thymidine analog 5-ethynyl-2’-deoxyuridine, which specifically stains schistosome stem cells) signal, and an increase in cell apoptosis. …”
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27220
Table_1_Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment.xlsx
Published 2022“…In support of this, we found decreased MDSC numbers, and increased numbers of CD4<sup>+</sup> T cells and natural killer T (NK-T) cells in lungs from cancer-bearing mice treated with S100A8. …”