Anti-Angiogenic Effects of a Mutant Endostatin: A New Prospect for Treating Retinal and Choroidal Neovascularization by Yujing Bai (170144)

“…The <i>in vitro</i> studies demonstrated that M-ES and PEG-M-ES inhibited HRMEC and HUVEC proliferation, migration, and tube formation more efficiently than ES. <i>In vivo</i>, a single intravitreal injection of M-ES and PEG-M-ES significantly decreased neovascularization in both the OIR and CNV animal models.…”

(A1 & A2) The GNM analysis performed on Ubiquitin (1 D3Z [104]). by Pemra Ozbek (452879)

“…<p>Experimentally determined hot spot residues (lines) and the long range interactions (sticks) are shown with the exact outcome of the fastest mode (blue) and the second fastest mode (red). Details are in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074320#pone.0074320.s010" target="_blank">Figure S10</a>. …”

Functional Characterization of <em>Aspergillus nidulans ypkA,</em> a Homologue of the Mammalian Kinase SGK by Ana Cristina Colabardini (385464)

“…Repression of <i>ypkA</i> caused decreased radial growth, a delay in conidial germination, deficient polar axis establishment, intense branching during late stages of growth, a lack of asexual spores, and a terminal phenotype. …”

Axial CT-scans of two different patients with a healthy BMI value of 22.1 kg/m². by Ekaterina Khristenko (17847064)

“…A—initial CT-scan on the level of L3 vertebral body; B—segmented CT scan; the area of muscle tissue was 179.2 cm²; the total area of fatty tissue was 102.5.2 cm².BA C and D: a patient with sarcopenia, BMI was normal with 22.1 kg/m², SMI was decreased with 36.2 cm²/m².DC A—initial CT image, performed at the L3 vertebral body level; B—segmented CT tomogram; the area of muscular tissue was 122.1 cm²; the total area of fatty tissue was 232.2 cm².…”

Optimized TMS produces high-quality DNA methylation data across a range of plexing strategies, input amounts, and protocol modifications. by Amy Longtin (21409957)

The pathway analysis of 348 genes in the hematopoietic cell lineage pathway (Fig 6A) using the KEGG pathway database and DAVID software. by Souma Suzuki (18554923)

Understanding of symptoms qualifying for COVID-19 testing among respondents who did not recall having experienced a test-qualifying symptom. by Mark S. Graham (4484317)

A PCA scatter plot visualizing the variability of shape directional asymmetry in the space of the PC1 and PC2 for males with percentage of variance. by Katarína Harnádková (16747606)

A PCA scatter plot visualizing the variability of shape directional asymmetry in the space of PC1 and PC2 for females with percentage of variance. by Katarína Harnádková (16747606)

2D and 3D AFM micrographs of fabricated samples (a) 5LZCM (b) 10LZCM (c) 15LZCM. by Md. Abu Daud (21485629)

Design of a Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells by Maciej Wnuk (825978)

“…MNP@CD26@17D-mediated ferroptosis might be executed by ferritinophagy as judged by elevated levels of the ferritinophagy marker NCOA4 and a decreased pool of ferritin. As 24 h treatment with MNP@CD26@17D did not induce hemolysis in human erythrocytes <i>in vitro</i>, this newly designed nanoplatform could be considered as an optimal multifunctional tool to target and eliminate senescent cells of skin origin, overcoming their apoptosis resistance.…”

Illumination distributions (a-c) and variations in illuminance values along the <i>x</i>-axis (d-f) of the RVL at different angles. by Fei Li (143236)

Spatial Resolved Surface Ozone with Urban and Rural Differentiation during 1990–2019: A Space–Time Bayesian Neural Network Downscaler by Haitong Sun (11667739)

“…Long-term exposure to ambient ozone (O₃) can lead to a series of chronic diseases and associated premature deaths, and thus population-level environmental health studies hanker after the high-resolution surface O₃ concentration database. …”

Fer-1 increased SLC7A11 and Nrf2 expression to resist <i>C. sinensis</i>-induced ferroptosis. by Haoyang Zhang (1706815)

Association between leisure time physical activity, confounders, and the left hip total aBMD (mg/cm²). by Saija Mikkilä (12004053)

A 60-year-old male with a hyperacute cardioembolic infarction fifteen hours after the onset. by Daichi Momosaka (6160418)

“…No signal abnormality is seen on <b>A:</b> T1-weighted image, <b>B:</b> T2-weighted image, and <b>C:</b> FLAIR image. …”

Table_1_A cytokine/PTX3 prognostic index as a predictor of mortality in sepsis.docx by Sadaf Davoudian (10829997)

“…After 5 days of hospitalization, PTX3 and cytokines, but not sIL-1R2 levels, decreased significantly, in parallel with a general improvement of clinical parameters. …”

Image_1_A cytokine/PTX3 prognostic index as a predictor of mortality in sepsis.tiff by Sadaf Davoudian (10829997)

“…After 5 days of hospitalization, PTX3 and cytokines, but not sIL-1R2 levels, decreased significantly, in parallel with a general improvement of clinical parameters. …”

<i>In silico</i> screening identifies doxazosin as a novel agonist for EphA2 receptor. by Aaron Petty (143170)

“…Note decreasing amount of EphA2 following ephrin-A1 and doxazosin treatment. …”

Image_2_A cytokine/PTX3 prognostic index as a predictor of mortality in sepsis.tiff by Sadaf Davoudian (10829997)

“…After 5 days of hospitalization, PTX3 and cytokines, but not sIL-1R2 levels, decreased significantly, in parallel with a general improvement of clinical parameters. …”