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45581
Withanolide A mediated transcriptional regulation of Nrf2 and GCLC expression depend on corticosterone signaling in hippocampus.
Published 2014“…Administration of Withanolide A alongwith exogenous corticosterone supplementation to the normoxic group decrease the Nrf2 as well as GCLC expression while inhibition of corticosterone synthesis using metyrapone during hypoxia reverses hypoxia induced downregulation of both Nrf2 and GCLC level. β-actin was used as a loading control. …”
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45582
Table4_LeishIF3d is a non-canonical cap-binding protein in Leishmania.XLSX
Published 2023“…<p>Translation of most cellular mRNAs in eukaryotes proceeds through a cap-dependent pathway, whereby the cap-binding complex, eIF4F, anchors the pre-initiation complex at the 5′ end of mRNAs driving translation initiation. …”
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45583
Supplementary Material for: Inadvertent intoxication with salbutamol, treated with hemodialysis: a case report and brief review of the literature
Published 2024“…Introduction Salbutamol is a moderately selective beta-2-adrenergic agonist. …”
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45584
Table_1_Predictors of Burnout Among Physicians: Evidence From a National Study in Portugal.DOCX
Published 2021“…Results show that 66% of physicians have high levels of emotional exhaustion, 33% high levels of depersonalization, and 39% high levels of decrease of personal accomplishment. Moreover, a first set of hierarchical multiple regression models with burnout symptoms reveals that organizational resources, demands of the relationship with the patients and of work schedule are consistently important predictors of emotional exhaustion and depersonalization on top of other theoretically relevant predictors. …”
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45585
Automated Calibration of a Poly(oxymethylene) Dimethyl Ether Oxidation Mechanism Using the Knowledge Graph Technology
Published 2021“…We find that calibration times are reduced, while accuracy is increased compared to manual calibration, achieving a 79% decrease in the objective function value, as defined in this study. …”
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45586
A Mononuclear Non-Heme Manganese(IV)–Oxo Complex Binding Redox-Inactive Metal Ions
Published 2013“…The reactivities of the Mn(IV)–oxo complex are markedly influenced by binding of Sc<sup>3+</sup> ions in oxidation reactions, such as a ∼2200-fold increase in the rate of oxidation of thioanisole (i.e., oxygen atom transfer) but a ∼180-fold decrease in the rate of C–H bond activation of 1,4-cyclohexadiene (i.e., hydrogen atom transfer). …”
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45587
Drug-induced inhibition of HMGA and EZH2 activity as a possible therapy for anaplastic thyroid carcinoma
Published 2024“…Then, treatment of the ATC cell lines with trabectedin and GSK126 resulted in a drastic induction of apoptotic cell death, which increased when the ATC cell lines were treated with a combination of both drugs. …”
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45588
A Functional Screen Identifies Specific MicroRNAs Capable of Inhibiting Human Melanoma Cell Viability
Published 2012“…Several miRNAs have already been shown to attenuate cancer phenotypes, by limiting proliferation, invasiveness, tumor angiogenesis, and stemness. Here, we employed a genome-scale lentiviral human miRNA expression library to systematically survey which miRNAs are able to decrease A375 melanoma cell viability. …”
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45589
Image8_LeishIF3d is a non-canonical cap-binding protein in Leishmania.TIF
Published 2023“…<p>Translation of most cellular mRNAs in eukaryotes proceeds through a cap-dependent pathway, whereby the cap-binding complex, eIF4F, anchors the pre-initiation complex at the 5′ end of mRNAs driving translation initiation. …”
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45590
Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach-3
Published 2011“…A distinct region follows, in which there is a significant decrease in the mutants robo, robo2, slit.robo and the transgenic UC2x. (1b) Medoids for the developmental time course. …”
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45591
R-loops accumulate in p.A382T TDP-43 mutated LCLs. Related to Fig 6.
Published 2020“…<p><b>A)</b> IF of LCL-CTL, LCL-TDP382, LCL-SALS using an anti-TDP-43 antibody and an anti-S9.6 antibody after paraformaldehyde fixation. …”
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45592
Can omega-3 fatty acids be beneficial in pediatric NAFLD? A systematic review and meta-analysis
Published 2023“…In addition, a significant improvement in liver steatosis assessed by ultrasonography and a decrease in BMI were observed. …”
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45593
Image_3_Influence of the Calcium Carbonate Shell of Coccolithophores on Ingestion and Growth of a Dinoflagellate Predator.tiff
Published 2021“…Calcified and decalcified cells of the coccolithophore species Emiliania huxleyi, Pleurochrysis carterae, and Gephyrocapsa oceanica were offered separately to the predator as well as in an initial ∼1:1 mixture. The decrease of the prey concentrations and predator abundances were monitored over a period of 48–72 h. …”
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45594
The Effects of Low-Dose Ketamine on Acute Pain in an Emergency Setting: A Systematic Review and Meta-Analysis
Published 2016“…Data were also extracted independently.</p><p>Results</p><p>A total of 6 trials involving 438 patients were included in the current analysis. …”
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45595
Image_2_Synbiotics Containing Nanoprebiotics: A Novel Therapeutic Strategy to Restore Gut Dysbiosis.TIF
Published 2021“…<p>A new formulation, nanoprebiotics [e.g., phthalyl pullulan nanoparticles (PPNs)], was demonstrated to enhance the antimicrobial activity of probiotics [e.g., Lactobacillus plantarum (LP)] in vitro through intracellular stimulation better than that by backbone prebiotics, which are commonly used. …”
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45596
Responses of Plant Community Composition and Biomass Production to Warming and Nitrogen Deposition in a Temperate Meadow Ecosystem
Published 2015“…However, its effects on plant community composition and biomass production are not well understood. A four-year field experiment was conducted to examine the effects of warming, nitrogen (N) addition, and their interactions on plant community composition and biomass production in a temperate meadow ecosystem in northeast China. …”
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45597
Image_6_Synbiotics Containing Nanoprebiotics: A Novel Therapeutic Strategy to Restore Gut Dysbiosis.TIF
Published 2021“…<p>A new formulation, nanoprebiotics [e.g., phthalyl pullulan nanoparticles (PPNs)], was demonstrated to enhance the antimicrobial activity of probiotics [e.g., Lactobacillus plantarum (LP)] in vitro through intracellular stimulation better than that by backbone prebiotics, which are commonly used. …”
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45598
Image5_LeishIF3d is a non-canonical cap-binding protein in Leishmania.TIF
Published 2023“…<p>Translation of most cellular mRNAs in eukaryotes proceeds through a cap-dependent pathway, whereby the cap-binding complex, eIF4F, anchors the pre-initiation complex at the 5′ end of mRNAs driving translation initiation. …”
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45599
A Novel Microbial Source Tracking Microarray for Pathogen Detection and Fecal Source Identification in Environmental Systems
Published 2015“…Perfect and mismatch probes established the specificity of the microarray in sewage, and fluorescence decrease of positive probes over a 1:10 dilution series demonstrated semiquantitative measurement. …”
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45600
Table_1_Self-Stigma in Parkinson's Disease: A 3-Year Prospective Cohort Study.pdf
Published 2022“…Purpose<p>Self-stigma is common in patients with Parkinson's disease (PD) and may lead to social isolation and delayed search for medical help. We conducted a 3-year prospective longitudinal study to investigate the development and evolution of self-stigma in patients with early stage PD and to explore the associated and predictive factors of self-stigma in PD.…”