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47081
Effects of UBE3A on Cell and Liver Metabolism through the Ubiquitination of PDHA1 and ACAT1
Published 2023“…Furthermore, a high-fat diet suppressed the expression of UBE3A in the mouse liver, which was associated with increased ACAT1 protein levels, while forced expression of UBE3A in the mouse liver resulted in decreased ACAT1 protein contents. …”
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47082
A review of algal toxin exposures on reserved federal lands and among trust species in the United States
Published 2021“…<p>Associated health effects from algal toxin exposure are a growing concern for human and animal health. …”
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47083
Curcumin affects the brain amyloid deposition histology patterns as a function of <i>Drosophila</i> genotype.
Published 2012“…DAPI staining from regions with widespread p-FTAA-positive aggregates were decreased. (K–O) Aβ<sub>1–42 E22G</sub> expressing flies at day 0, day 5, and day 10, showed a spot-like staining from both p-FTAA and the Aβ specific antibody, but a weaker p-FTAA staining was apparent (c.f. …”
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47084
Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population
Published 2022“…Maternal (n = 167) and infant (n = 172) toenail and placenta (n = 115) samples for prenatal Pb exposure were obtained from participants in a US birth cohort, and methylation and hydroxymethylation data were quantified using the Illumina Infinium MethylationEPIC BeadChip. …”
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47085
X‑Ray Conformation and Structure–Activity Relationships of MA026, a Reversible Tight Junction Opener
Published 2023“…MA026, a cyclic lipodepsipeptide, opens the tight junction (TJ) probably via binding to claudin-1. …”
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47086
Image_1_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.TIFF
Published 2019“…<p>Postoperative delirium is a frequent and debilitating complication, especially amongst high risk procedures such as orthopedic surgery, and its pathogenesis remains unclear. …”
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47087
Differential Expression of miRNA-192 is a Potential Biomarker for HIV Associated Immune Recovery Uveitis
Published 2022“…</p> <p>HIV+ patients were classified into four groups (A, B, C and D) with and without ocular manifestations, with follow-up over a year. …”
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47088
APL1 protects <i>A. gambiae</i> against wild <i>P. falciparum</i>.
Published 2009“…<p>A) Expression of the APL1 gene family detected by RT-PCR using primers that amplify a conserved region shared by all three APL1 genes. …”
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47089
Image_7_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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47090
Image 1_Surface characteristics and bioactivity of titanium preserved in a baicalin-containing saline solution.tif
Published 2025“…Objective<p>This study aimed to develop a baicalin (BA)-containing storage saline solution and investigate their effects on the physicochemical properties and bioactivity of sandblasted with large grit and acid-etched (SLA) titanium surfaces.…”
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47091
Table_3_Targeting metabolic pathways: a novel therapeutic direction for type 2 diabetes.docx
Published 2023“…</p>Results<p>Our findings revealed a reduction in both the species diversity and abundance of intestinal flora in T2DM mice, with significantly decreased levels of beneficial bacteria such as Lactobacillus and significantly increased levels of harmful bacteria such as Helicobacter pylori. …”
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47092
Could the Extent of Lymphadenectomy Be Modified by Neoadjuvant Chemotherapy in Cervical Cancer? A Large-Scale Retrospective Study
Published 2015“…</p><p>Methods</p><p>Patients with FIGO stage IB1-IIB who underwent radical surgery with or without NACT were enrolled (3527 patients). A matched-case comparison design was used to compare the effects of NACT on lymph node metastasis.…”
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47093
Image_8_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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47094
Amino Acid Substitutions of MagA in <em>Klebsiella pneumoniae</em> Affect the Biosynthesis of the Capsular Polysaccharide
Published 2012“…The G334A mutant remained mucoid with decreased CPS production, but its virulence was significantly reduced <em>in vivo</em>. …”
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47095
Denitrifying Bacterial Communities Affect Current Production and Nitrous Oxide Accumulation in a Microbial Fuel Cell
Published 2013“…Current production decreased from 15.0 A·m<sup>−3</sup> NCC (Net Cathodic Compartment), when nitrate was used as an electron acceptor, to 14.1 A·m<sup>−3</sup> NCC in the case of nitrite. …”
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47096
<i>CCHa2</i> is a selective nutrient-sensitive hormone derived from peripheral tissues.
Published 2015“…<p>(A) RT-qPCR was performed on RNA extracted from larval tissues. …”
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47097
Table 1_Sex disparities in the risk of intracranial aneurysm rupture: a case–control study.docx
Published 2024“…Compared with males, females had a higher risk of ruptured IA [odds ratio, 1.72 (95% confidence interval, 1.38–2.14)]. …”
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47098
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury
Published 2024“…Mitogen-activated protein kinase-interacting protein kinases (MNKs) and phosphorylate eukaryotic initiation factor 4E (p-eIF4E) play a critical role in regulating mRNA translation and protein synthesis associated with the development of cancer, metabolism, and inflammation. …”
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47099
Image_1_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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47100
Data_Sheet_2_The mirror mechanism in schizophrenia: A systematic review and qualitative meta-analysis.pdf
Published 2022“…Previous studies report its malfunction in autism, opening doors to investigate the underlying pathophysiology of the disorder in a more elaborate way and coming up with new rehabilitation methods. …”