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47441
RhoB Acts as a Tumor Suppressor That Inhibits Malignancy of Clear Cell Renal Cell Carcinoma
Published 2016“…These findings show that RhoB may play a tumor suppressive role in ccRCC cells, raising its potential value in futural therapeutic target for the patients of ccRCC.…”
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47442
Natural Form of Noncytolytic Flexible Human Fc as a Long-Acting Carrier of Agonistic Ligand, Erythropoietin
Published 2011“…<div><p>Human IgG1 Fc has been widely used as a bioconjugate, but exhibits shortcomings, such as antibody- and complement-mediated cytotoxicity as well as decreased bioactivity, when applied to agonistic proteins. …”
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47443
Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial
Published 2025“…<p dir="ltr">Context: Type 2 diabetes (T2D) increases fragility fracture risk despite normal/elevated aBMD, attributed to compromised bone microarchitecture. …”
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47444
Table_2_Prediction of Soil Formation as a Function of Age Using the Percolation Theory Approach.XLSX
Published 2018“…Nonetheless, the model is able to generate soil depth and confirms decreasing production rates with age. A steady state for soils is not reached before about 100 kyr to 1 Myr</p>…”
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47445
Data_Sheet_1_Extracutaneous features and complications of the Ehlers-Danlos syndromes: A systematic review.docx
Published 2023“…Introduction<p>The Ehlers-Danlos syndromes (EDS) comprise a group of inherited connective tissue disorders presenting with variable fragility to skin, soft tissue, and certain internal organs, which can cause significant complications, particularly arterial rupture, bowel perforation and joint difficulties. …”
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47446
Table1_BTBD10 is a Prognostic Biomarker Correlated With Immune Infiltration in Hepatocellular Carcinoma.DOCX
Published 2022“…<p>Background: BTBD10 serves as an activator of Akt family members through decreasing the protein phosphatase 2A-mediated dephosphorylation. …”
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47447
OVA66, a Tumor Associated Protein, Induces Oncogenic Transformation of NIH3T3 Cells
Published 2014“…Analysis of PI3K/AKT and ERK1/2 MAPK signaling pathways by serum stimulation indicated hyperactivation of AKT and ERK1/2 in NIH3T3-flagOVA66 cells compared with NIH3T3-mock cells, while a decreased level of p-AKT and p-ERK1/2 were observed in OVA66 knocked down HeLa cells. …”
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47448
Table_1_The IAG-Switch and Further Transcriptomic Insights Into Sexual Differentiation of a Protandric Shrimp.xlsx
Published 2020“…<p>The insulin-like androgenic gland hormone (IAG) secreted from the androgenic gland (AG) is a unique endocrine controller (the IAG-switch) of crustacean sexual differentiation. …”
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47449
Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy
Published 2017“…<div><p>Interleukins-6 (IL-6)/GP130 signaling pathway represents a promising target for cancer therapy due to its critical role in survival and progression of multiple types of cancer. …”
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47450
A Comprehensive Study of Extended Tetrathiafulvalene Cruciform Molecules for Molecular Electronics: Synthesis and Electrical Transport Measurements
Published 2014“…The molecules were subjected to a comprehensive study of their conducting properties as well as their photophysical and electrochemical properties in solution. …”
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47451
Image_2_Schlafen family is a prognostic biomarker and corresponds with immune infiltration in gastric cancer.tif
Published 2022“…We isolated three samples of peripheral blood mononuclear cell (PBMC) and activated T cells; the results showed the expression of SLFN family members decreased significantly when T cell active. In conclusion, the SLFN family of proteins may act as a prognostic indicator of GC and is associated with immune cell infiltration and immune checkpoint expression in GC. …”
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47452
Construction of a prognostic model based on genome-wide methylation analysis of miRNAs for hepatocellular carcinoma
Published 2024“…<p><b>Aim:</b> Using the methylation level of miRNA genes to develop a prognostic model for patients with hepatocellular carcinoma (HCC). …”
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47453
A 'meta-analysis' of effects of post-hatch food and water deprivation on development, performance and welfare of chickens
Published 2017“…<div><p>A ‘meta-analysis’ was performed to determine effects of post-hatch food and water deprivation (PHFWD) on chicken development, performance and welfare (including health). …”
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47454
Dermatomyositis and Polymyositis in the Intensive Care Unit: A Single-Center Retrospective Cohort Study of 102 Patients
Published 2016“…Factors associated with increased ICU mortality included a diagnosis of DM (including CADM), a high APACHE II score, the presence of ARF, a decreased PaO<sub>2</sub>/FiO<sub>2</sub> ratio, and a low lymphocyte count at the time of ICU admission.…”
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47455
The bacterial protein CNF1 as a new strategy against <i>Plasmodium falciparum</i> cytoadherence
Published 2019“…On the other hand, flow cytometry experiments show that cytoadherence reversion induced by CNF1 occurs in parallel with a decreased ICAM-1 receptor expression on the cell surface, suggesting the involvement of a toxin-promoted endocytic activity in such a response. …”
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47456
Exploring population responses to environmental change when there is never enough data; a factor analytic approach
Published 2018“…This decreases the number of parameters to estimate and, where the covariance is positive, the latent variable can be interpreted as a measure of environmental quality. …”
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47457
<i>Smp_248100</i> is specifically required for vitellaria maturation following pairing with a male worm.
Published 2019“…<p>(A) qPCR showing decreased <i>Smp_248100</i> transcript levels in <i>Smp_248100(RNAi)</i> versus <i>control(RNAi)</i>. …”
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47458
Image_4_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.tiff
Published 2021“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”
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47459
Mice with a Targeted Deletion of the Type 2 Deiodinase Are Insulin Resistant and Susceptible to Diet Induced Obesity
Published 2011“…Consistent with this, serum free fatty acids and β-hydroxybutyrate were lower in D2KO mice on a HFD, while hepatic triglycerides were increased and glycogen content decreased. …”
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47460
A Meta-Analysis of <em>Caspase 9</em> Polymorphisms in Promoter and Exon Sequence on Cancer Susceptibility
Published 2012“…Polymorphisms in promoter and exon of <em>caspase 9</em> were shown to confer genetic susceptibility to multiple cancers, but the results were inconsistent. To accomplish a more precise estimation of the relationship, a meta-analysis was performed.…”