Protective expansion of PD-1⁺, Tim3⁺ and KLRG1⁺ CD8⁺ T cells peaks when viral loads decrease during long term low dose EBV infection. by Bithi Chatterjee (179700)

A Recyclable, Immobilized Analogue of Benzotetramisole for Catalytic Enantioselective Domino Michael Addition/Cyclization Reactions in Batch and Flow by Javier Izquierdo (1333773)

“…The deactivation of <b>5</b> by species present during the catalytic process has been studied, and pivaloyl chloride (required for the activation of the arylacetic acid) has been identified as the main source of deactivation. A simple experimental protocol taking this fact into account has allowed the multiple recycling of <b>5</b> with only a marginal decrease in catalytic activity and the implementation of a continuous flow process where the activation of phenylacetic acid (residence time 14.2 min), the asymmetric domino Michael addition/cyclization reaction (residence time 7.5 min), and aqueous workup are performed sequentially, delivering the dihydropyridinone product as a clean dichloromethane solution (0.54 mmol catalyst sample; 11 h operation; <b>8a</b> (4.44 g, >99.9% ee)). …”

Anticipated burden and mitigation of carbon-dioxide-induced nutritional deficiencies and related diseases: A simulation modeling study by Christopher Weyant (5478515)

“…<div><p>Background</p><p>Rising atmospheric carbon dioxide concentrations are anticipated to decrease the zinc and iron concentrations of crops. …”

A Recyclable, Immobilized Analogue of Benzotetramisole for Catalytic Enantioselective Domino Michael Addition/Cyclization Reactions in Batch and Flow by Javier Izquierdo (1333773)

“…The deactivation of <b>5</b> by species present during the catalytic process has been studied, and pivaloyl chloride (required for the activation of the arylacetic acid) has been identified as the main source of deactivation. A simple experimental protocol taking this fact into account has allowed the multiple recycling of <b>5</b> with only a marginal decrease in catalytic activity and the implementation of a continuous flow process where the activation of phenylacetic acid (residence time 14.2 min), the asymmetric domino Michael addition/cyclization reaction (residence time 7.5 min), and aqueous workup are performed sequentially, delivering the dihydropyridinone product as a clean dichloromethane solution (0.54 mmol catalyst sample; 11 h operation; <b>8a</b> (4.44 g, >99.9% ee)). …”

Table_1_Suicide risk among female breast cancer survivors: A population–based study.docx by Jian Shi (141852)

“…Female breast cancer survivors had a higher risk of suicide than the general population (SMR = 1.19; 95% CI (1.08–1.31)). …”

Image_1_Suicide risk among female breast cancer survivors: A population–based study.tif by Jian Shi (141852)

“…Female breast cancer survivors had a higher risk of suicide than the general population (SMR = 1.19; 95% CI (1.08–1.31)). …”

A Recyclable, Immobilized Analogue of Benzotetramisole for Catalytic Enantioselective Domino Michael Addition/Cyclization Reactions in Batch and Flow by Javier Izquierdo (1333773)

“…The deactivation of <b>5</b> by species present during the catalytic process has been studied, and pivaloyl chloride (required for the activation of the arylacetic acid) has been identified as the main source of deactivation. A simple experimental protocol taking this fact into account has allowed the multiple recycling of <b>5</b> with only a marginal decrease in catalytic activity and the implementation of a continuous flow process where the activation of phenylacetic acid (residence time 14.2 min), the asymmetric domino Michael addition/cyclization reaction (residence time 7.5 min), and aqueous workup are performed sequentially, delivering the dihydropyridinone product as a clean dichloromethane solution (0.54 mmol catalyst sample; 11 h operation; <b>8a</b> (4.44 g, >99.9% ee)). …”

RPS3a enhances HBx-induced NF-κB signaling via its chaperoning activity. by Keo-Heun Lim (50946)

“…(<b>B–C</b>) Decrease of punctate expression of HBx-GFP by RPS3 in a dose-dependent manner. …”

Some primate species encode a CD4 that functions as an entry receptor for an early isolate of HIV-1. by Cody J. Warren (563898)

“…<p>(A) Cryo-EM structure of the Envelope (Env) trimer (blue) from a prototypic early HIV-1 isolate (BG505 [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.ref009" target="_blank">9</a>]) in complex with human CD4 (tan) (PDB:5U1F) [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.ref028" target="_blank">28</a>]. …”

A Family of Vanadate Esters of Monoionized and Diionized Aromatic 1,2-Diols: Synthesis, Structure, and Redox Activity by Bharat Baruah (1345038)

“…In solution each ester gives rise to a single ⁵¹V NMR signal (no diastereoisomers), which generally shifts downfield with a decrease in the ester LMCT band energy. …”

Image_2_Suicide risk among female breast cancer survivors: A population–based study.tif by Jian Shi (141852)

“…Female breast cancer survivors had a higher risk of suicide than the general population (SMR = 1.19; 95% CI (1.08–1.31)). …”

Genes and a non-coding RNA found to be down-regulated in the serovar D CT135-negative strain. by Vítor Borges (774790)

“…As in the present study it was found to be strongly down-regulated even with a slight <i>pgp4</i> expression decrease, we assumed this result as a consequence of CT135 loss.…”

Decrease in islet regularity and size associated with global pancreatic apoptosis (Tunel⁺) 2–3 days after oral inoculation of weaned C57Bl/6 mice with rhesus RV (filled... by Leonard C. Harrison (7313129)

DataSheet1_Ambient Air Quality Standards and Policies in Eastern Mediterranean Countries: A Review.docx by Sasan Faridi (9277880)

“…We estimated that the reduction of annual mean PM_2.5 exposure level to the AQG level (5 μg m⁻³) would be associated with a decrease of all natural-cause mortality in adults (age 30+) by 16.9%–42.1% in various EMR countries. …”

Operons with an upstream FNR ChIP-seq peak and a FNR-dependent change in expression under GMM. by Kevin S. Myers (424665)

“…Each operon was determined to have a significant (>2 fold) increase (+), decrease (−) and no change (o) in WT −O₂ relative to WT +O₂ (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003565#pgen.1003565.s018" target="_blank">Table S12</a>).…”

UBKIs possess broad antiviral activity, are effective in primary cells, and impose a barrier against resistance development. by Markus Lesch (6475409)

“…The calculation of p-values revealed a significant decrease of log-transformed virus-titers in the regorafenib and sorafenib-treated groups relative to the DMSO control at the indicated time points: *: p-value ≤ 0.05. …”

endoR captures interactions predictive of an artificial phenotype from a random forest fitted on real metagenomes. by Albane Ruaud (14259687)

“…<p>A-E: Real metagenomes with an artificial phenotype (AP): samples were separated into 4 groups (labelled a-d), a binary response variable (‘1’ = blue, ‘-1’ = yellow) was simulated so that it could be predicted from a set of decisions based on the ‘group’ categorical feature and specific, randomly chosen microbial abundance features (e.g., ‘Alistipes A’). …”

Gene set enrichment analysis revealed NF-κB signaling as a potential downstream regulator of Efp. by Wataru Sato (149080)

“…(<b>D</b> and <b>E</b>) Decrease of <i>IL6ST</i> and <i>IL18</i> mRNA levels in siEfp #A-treated tumors <i>in vivo</i>. …”

Data from: Large subsurface carbon stocks in a long-term no-tillage site are vulnerable to potential mineralization by Qiuping Peng (20147290)

“…Model comparisons supported the use of a 3-pool linear decay model with a single set of k-values optimized for all samples collectively, and no requirement to allocate total soil organic carbon (SOC) across the pools. …”

Probabilistic results of the incremental cost-effectiveness pairwise between various treatments without NVBP for a simulation of 100,000 iterations. The y-axis represents the incre... by Yi Lin (49406)