Disrupted Small-World Brain Networks in Moderate Alzheimer's Disease: A Resting-State fMRI Study by Xiaohu Zhao (175664)

“…<div><p>The small-world organization has been hypothesized to reflect a balance between local processing and global integration in the human brain. …”

Pediculectomy and fenestration for spinal cord decompression of the lumbar spine of a bush dog (Speothos venaticus) - case report by P.V.T. Marinho (5383583)

“…<div><p>ABSTRACT A captive adult male bush dog (Speothos venaticus) was referred to our Veterinary Medical Teaching Hospital from a local zoo due to a two-week history of progressive hind limb gait impairment and ataxia, non-responsive to clinical management. …”

Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor by LiMei Wang (5651041)

“…<div><p>The multifunctional signaling protein p75 neurotrophin receptor (p75^NTR) is a central regulator and major contributor to the highly invasive nature of malignant gliomas. …”

Data_Sheet_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.PDF by Ran Fang (533948)

“…<p>Pyoderma gangrenosum (PG) is a rare, destructive inflammatory skin disease of which a painful nodule or pustule breaks down to form a progressively enlarging ulcer. …”

Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties by Keigo Hirai (12095443)

“…Through IAM chromatography analysis and in vivo brain penetration assay of the HyTs, we discovered a brain-permeable HyT. Our results and mechanistic analysis indicate that conversion of protein degraders into HyTs could be a useful approach to improve their drug-like properties.…”

Table_1_A Novel Biallelic STING1 Gene Variant Causing SAVI in Two Siblings.doc by Malak Ali Alghamdi (9960260)

“…Exome sequencing revealed a novel homozygous NM_198282.3: c.841C>T; p.(Arg281Trp) variant in exon 7 of the STING1 gene. …”

Cross-Linking Porcine Pericardium by 3,4-Dihydroxybenzaldehyde: A Novel Method to Improve the Biocompatibility of Bioprosthetic Valve by Binggang Wu (9925999)

“…In conclusion, the properties of bioprosthetic valves could be effectively improved by processing valves with a DHBA-based cross-linking method.…”

Cone densities and opsin expression patterns along a dorso-ventral strip in temporal retina (aardvark 1). by Leo Peichl (219825)

“…<p>(A) Cone density along the dorso-ventral strip (region 1 in the retina scheme <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0314252#pone.0314252.s001" target="_blank">S1 Fig</a>) decreases with distance from the streak, the horizontal band of reduced pigmentation in the fundus (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0314252#pone.0314252.g003" target="_blank">Fig 3</a>). …”

Experimental and computational studies on a protonated 2-pyridinyl moiety and its switchable effect for the design of thermolytic devices by Jolanta Brzezinska (1456774)

“…Such protonation seems to be a major inhibitory factor in the thermal removal of 2-pyridynyl TPG by the “chemical switch” approach and decreases the aromaticity of the pyridine ring. …”

Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors by Jumpei Aida (1399486)

“…Monoacylglycerol lipase (MAGL) is a major serine hydrolase that hydrolyzes 2-arachidonoylglycerol (2-AG) to arachidonic acid (AA) and glycerol in the brain. …”

Changes in dietary habits and eating behaviors during COVID-19 induced confinement: A study from Jordan by Alomari, Mahmoud A.

“…Among these changes, they have increased (p < 0.05) the prevalence of fruit and vegetable, immune boosters, water, and hot beverage consumption, as well as decreased (p < 0.05) eating in restaurants and fatty food consumption, indicating a positive change. …”
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Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis by Paravattil, Bridget

“…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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Image_2_Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.JPEG by Ling Hu (374570)

“…<p>Schizophrenia (SCZ) is a chronic and severe mental disease that affects around 1% of the population. …”

HuR specifically represses translation through the IGF-IR 5′-UTR in a concentration-dependent manner by Zheng Meng (9293)

“…The FLuc RNA (5 ng) was used as a control. The results are expressed relative to the control reactions without HuR. () translation with recombinant HuR protein. …”

Deletion of <i>Kif3a</i> in early stages of forebrain development leads to increased brain size. by John Snedeker (3836410)

“…<p>(A-L) <i>Foxg1-Cre</i> was used to delete a conditional allele of <i>Kif3a</i> and the forebrain was enlarged at E14.5 (B) and E18.5 (H,J,). …”

Image_1_Case report: A case of sepsis caused by rickettsial infection-induced hemophagocytic syndrome.tif by Yanli Cao (4418011)

“…HLH encompasses a group of clinical syndromes marked by the overproduction of inflammatory cytokines. …”

DataSheet1_Learning the Quantum Centroid Force Correction in Molecular Systems: A Localized Approach.docx by Chuixiong Wu (12565498)

“…<p>Molecular mechanics (MM) is a powerful tool to study the properties of molecular systems in the fields of biology and materials science. …”

Image_2_Case report: A case of sepsis caused by rickettsial infection-induced hemophagocytic syndrome.tif by Yanli Cao (4418011)

“…HLH encompasses a group of clinical syndromes marked by the overproduction of inflammatory cytokines. …”

Embryonic stem cell (ESC) lines derived from type <i>a</i> 4n blastocysts. by Duancheng Wen (551901)

“…The efficiency of ESC derivation for type <i>a</i> 4n blastocysts is similar to that for 2n blastocysts, while the efficiency for type <i>b</i> 4n blastocysts is significantly decreased (<i>P</i><0.01). …”

Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx by Yuan Wang (14955)

“…<p>Malignant melanoma ranks among the most aggressive forms of cancer, with high rates of metastasis and recurrence, as well as a poor prognosis. Consequently, an urgent need is to develop novel precision therapeutic strategies and corresponding drugs. …”