HDACi-resistant HCT-R cells exhibit high expression levels of pAKT, a downstream effector of WNT5A and ROR2. by Michael Bordonaro (340595)

“…<p>(A) HDACi-resistant HCT-R cells express higher levels of pAKT than HDACi-sensitive HCT-116 cells. …”

NO inhibition (L-NAME) <i>in viv</i>o results in increasing outward current in some PNs (A, B, C) and decreasing inward current in others (D, E, F). by Mark Higgins (312833)

“…<p><b>A</b>. Representative traces of net outward currents elicited by the depolarization protocol (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042556#pone-0042556-g001" target="_blank">figure 1</a>) before (saline), 30 min. after treatment with L-NAME, and the difference (L-NAME - Saline). …”

Illustrative images of the processing of a myocardial perfusion study in a patient with Chagas disease. by Káryta Suely Macêdo Martins (22404155)

Results of a standardized factor loadings of a measurement model for PTSD symptoms (N = 775), Northwest, Ethiopia, 2021. by Marelign Tilahun Malaju (12401482)

A high-calorie, high-carbohydrate diet results in glucose intolerance but improved insulin sensitivity. by Tara Jois (3592874)

Biphasic Somatic A-Type K⁺ Channel Downregulation Mediates Intrinsic Plasticity in Hippocampal CA1 Pyramidal Neurons by Sung-Cherl Jung (261358)

“…Recent evidence shows that dendritic excitability can be enhanced by an activity-dependent decrease in the activity of A-type K⁺ channels. …”

Circulating Treg (A), Th1(B) and Th2 (C) cells were evaluated by flow cytometry. by Hongfei Lou (746299)

<i>M. plutonius</i> culture on a pooled sample of 3 bees collected from field colonies. by Midhun Sebastian Jose (19336846)

Decreased NO₃^- concentration in the <i>clca-2</i> mutant accelerated nitrogen (N) assimilation, resulting in higher N use efficiency (NUE). by Qiong Liao (496101)

C3a/C3 dot blot. by Sahra Pajenda (3463001)

“…Patient (<b>o</b>) did not survive this episode due to multiorgan failure the same day as urine sample #5 was collected. Shown is a representative experiment out of four. Left panel of the figure represents patients with decreasing urinary C3a/C3 levels. …”

Supplementary Material for: Topo-Proteomic in situ Analysis of Psoriatic Plaque under Efalizumab Treatment by Bonnekoh B. (4106116)

“…At the ‘EfaBS-centered, double colocation level’ a corresponding decrease was observed for CD2, CD3, CD4, CD8, CD11a, CD13, CD26, CD44, CD45, CD45R0, CD54, CD62L, HLA-DR, and TIA-1. …”

This is the raw data of Western blot in Met-5A cell. by Yangyang Yin (14323701)

Subjects:

Losartan is not neuroprotective in a crush model of axon injury. by Harry A. Quigley (695817)

A Membrane Biophysics Perspective on the Mechanism of Alcohol Toxicity by Marcus K. Dymond (1271937)

“…Structure–toxicity relationships for alcohols ranging from methanol to hexadecanol are collated, and estimates of alcohol toxicity per alcohol molecule in the cell membrane are made. The latter reveal a minimum toxicity value per molecule around butanol before alcohol toxicity per molecule increases to a maximum around decanol and subsequently decreases again. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. …”

3D snapshots of the tumor system with single-agent BHQ880 treatment at (a) time step 40, (b) time step 50 and (c) time step 120. by Minna Qiao (836556)