Cytotoxicity and total glycosaminoglycan (GAG) content. by Melissa A. MacIver (12850566)

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Gross photography and construct weight for initial chondrogenic screening. by Melissa A. MacIver (12850566)

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The CYP3A1mRNA and protein expressions in the small intestine and the liver (n = 3). by Xiangchen Li (512737)

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LM11A-31 reverses dystrophy of cholinergic neurites that occurs with aging in APP^L/S mice. by Danielle A. Simmons (621167)

“…<p>Quantitative analysis of the effect of aging showed that 13–14 month old vehicle-treated APP^L/S (APP) mice had ChAT neurites in basal forebrain with decreased (<b><i>A</i></b>) length and (<b><i>B</i></b>) area and had dystrophic neurite clusters in cortex that occupied more area (<b><i>C</i></b>) and were larger (<b><i>D</i></b>) compared to the 9–11 month old APP Veh mice. …”

Effects of miR-450a-3p on zygote cleavage. by Min Luo (258201)

“…(<b>C</b>) Western blot analysis of Bub1 protein from embryos. There was a significant decrease in Bub1 protein expression in embryos microinjected with miR-450a-3p relative to the mimic control or the untreated control. …”

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in <i>mdx</i> and <i>Cmah-/-mdx</i> mouse models of Duchenne muscular dystroph... by Alison M. Blain (5409806)

“…<p><b>A-D: P-PMO has direct effects and indirect vascular effects on the myocardium.…”

Sensitivity of N2A stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…(I–L) The number of N2A-pCMV-HSVtk cells was decreased in a dose-dependent manner. …”

Sensitivity of U251 stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…<p>U251, U251-pCMV-HSVtk, and U251-pGFAP-HSVtk cells were treated with 0, 1, 5, or10 μg/ml of GCV for 5 days. (A–D) Live-cell phase images of U251 parent cells displayed no cytotoxicity up to 10 μg/ml of GCV. …”

3D spheroid culture condition enhances CXCR4 surface expression. by Keven Huang (675616)

“…When grown under 3D spheroids, all of the cell lines showed a dramatic shift in CXCR4 surface expression. (<b>D</b>) Tet-inducible shRNA knockdown of CXCR4 (shCXCR4) in HeyA8 cells under 3D spheroid condition showed decreased CXCR4 surface expression (Grey line) indicating the specificity of increased CXCR4 surface expression under 3D spheroids. …”

Phospho-ERK inhibition increases CXCR4 surface expression. by Keven Huang (675616)

“…The phospho-ERK assay showed decreasing levels with increasing U0126. Flow cytometry analysis showed a dose dependent increase in CXCR4 expression. …”

Patterns of nestin, GFAP, and βIII-tubulin expression in U251-pCMV-HSVtk cells. by Elizabeth Wei-Chia Luo (11250668)

“…Immunocytochemistry of nestin (A–F), GFAP (G–L), and βIII-tubulin (M–R, M′–R′) was performed to characterize the identity of surviving cells. …”

LM11A-31 prevents atrophy of cholinergic neurites in basal forebrain of late-stage APP^L/S mice. by Danielle A. Simmons (621167)

“…Scale bar in drawing under A = 40 µm. Quantitative analysis showed that treating late-stage APP^L/S mice with LM11A-31 for 1 month prevented the decreases in (<b><i>D</i></b>) length, (<b><i>E</i></b>) surface area, and (<b><i>F</i></b>) branching of cholinergic neurites in basal forebrain, although the latter measure did not reach statistical significance. …”

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells by Zachary B. Davis (848829)

“…The NKG2A/CD94 iNKR suppresses NK cell responses through recognition of the non-classical MHC-I, HLA-E. …”

ARTEMIN Promotes <em>De Novo</em> Angiogenesis in ER Negative Mammary Carcinoma through Activation of TWIST1-VEGF-A Signalling by Arindam Banerjee (118618)

“…Functional inhibition of ARTN by siRNA decreased the angiogenic effects of ER-MC cells. Bevacizumab (a humanized monoclonal anti-VEGF-A antibody) partially inhibited the ARTN mediated angiogenic effects of ER-MC cells and combined inhibition of ARTN and VEGF-A by the same resulted in further significant decrease in the angiogenic effects of ER-MC cells. …”

Impact of gcn5-F221A on the growth rate of GCN5 synthetic lethal genes. by Amanda M. Lanza (168454)

“…The majority of the genes show a moderate decrease in growth rate as mutant expression is increased while several showed no growth rate changes. …”

Data_Sheet_1_Biochemical, Metabolomic, and Genetic Analyses of Dephospho Coenzyme A Kinase Involved in Coenzyme A Biosynthesis in the Human Enteric Parasite Entamoeba histolytica.P... by Arif Nurkanto (6032693)

“…Furthermore, metabolomic analysis showed that suppression of Ehdpck gene expression also caused decrease in the level of acetyl-CoA, and metabolites involved in amino acid, glycogen, hexosamine, nucleic acid metabolisms, chitin, and polyamine biosynthesis. …”

Data_Sheet_2_Biochemical, Metabolomic, and Genetic Analyses of Dephospho Coenzyme A Kinase Involved in Coenzyme A Biosynthesis in the Human Enteric Parasite Entamoeba histolytica.P... by Arif Nurkanto (6032693)

“…Furthermore, metabolomic analysis showed that suppression of Ehdpck gene expression also caused decrease in the level of acetyl-CoA, and metabolites involved in amino acid, glycogen, hexosamine, nucleic acid metabolisms, chitin, and polyamine biosynthesis. …”

Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment-3 by Iliya Lefterov (73826)

“…<p><b>Copyright information:</b></p><p>Taken from "Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment"</p><p>http://www.molecularneurodegeneration.com/content/2/1/20</p><p>Molecular Neurodegeneration 2007;2():20-20.…”

Combined inhibition of Mcl-1 and A1 results in efficient induction of apoptosis in 1205Lu melanoma cells. by Daniela Senft (334417)

“…<p>(A) 1205Lu melanoma cells were transfected with A1- or Mcl-1-specific siRNAs or control siRNAs as indicated. …”

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for acute respiratory infections treated in a census of 379 clinics providing service... by Bradley H. Wagenaar (311527)