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9481
Dysfunction of Organic Anion Transporting Polypeptide 1a1 Alters Intestinal Bacteria and Bile Acid Metabolism in Mice
Published 2012“…The data demonstrate that Oatp1a1-null mice : (1) have similar bile flow and BA concentrations in bile as WT mice; (2) have a markedly different BA composition in the intestinal contents, with a decrease in conjugated BAs and an increase in unconjugated BAs; (3) have BAs in the feces that are more deconjugated, desulfated, 7-dehydroxylated, 3-epimerized, and oxidized, but less 7-epimerized; (4) have 10-fold more bacteria in the small intestine, and 2-fold more bacteria in the large intestine which is majorly due to a 200% increase in <em>Bacteroides</em> and a 30% reduction in <em>Firmicutes</em>; and (5) have a different urinary excretion of bacteria-related metabolites than WT mice. …”
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9482
Table_1_Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA.pdf
Published 2019“…Second, in our biochemical assays, increasing RelA concentration does not decrease the enzyme activity, as would be expected in the case of efficient auto-inhibition via dimerization. …”
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9483
Ectopically expressed hNaa40p in yeast acetylates histone H4 but not H2A <i>in vivo</i>.
Published 2011“…Various N-acetylated forms of these histone N-termini were detected in all samples analyzed. A decrease of 5 Da, corresponds with the gain of an extra <i>in vivo</i> N-acetyl group (i.e. all free amines were <i>in vitro</i> N-acetylated using <sup>13</sup>C<sub>2</sub>D<sub>3</sub>-NHS acetate; i.e. adding a 5 Da heavier acetyl group to free amines). …”
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9484
A representative ultrasound axis image.
Published 2024“…This suggests that low-pressure VM can be a simple and cost-effective method to reduce cerebrovascular stiffness in a brief interval, without the need for specific environmental conditions.…”
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9485
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9486
Image_3_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.tif
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9487
Data Sheet 1_Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss.docx
Published 2025“…Using primary cultures of rat hippocampal neurons, we showed that S100B partially reverts Aβ-induced cofilin-actin rods (synapse disruptors), and rescues the decrease in active synapses and post-synaptic marker (PSD-95), imposed by Aβ peptide. …”
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9488
Image_1_Teicoplanin associated gene tcaA inactivation increases persister cell formation in Staphylococcus aureus.JPEG
Published 2023“…The RNA-seq data revealed a significant decrease in tcaA (p = 0.008) and tcaB (p = 0.04) expression while tcaR was not significantly altered. …”
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9489
Table_1_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.xlsx
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9490
Table_1_Mechanism of the Potential Therapeutic Candidate Bacillus subtilis BSXE-1601 Against Shrimp Pathogenic Vibrios and Multifunctional Metabolites Biosynthetic Capability of th...
Published 2020“…Thus, therapeutic strategies are highly needed to decrease the risk of vibriosis outbreaks. Herein, we initially identified that the growth of the causative agent of AHPND, Vibrio parahaemolyticus (VP<sub>AHPND</sub>) and other vibrios in Pacific white shrimp (Litopenaeus vannamei) was inhibited by a Bacillus subtilis strain BSXE-1601. …”
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9491
Table_3_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.xlsx
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9492
Table_4_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.xlsx
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9493
Image_2_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.TIF
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9494
Data_Sheet_1_Studies on the Regulation of (p)ppGpp Metabolism and Its Perturbation Through the Over-Expression of Nudix Hydrolases in Escherichia coli.PDF
Published 2020“…We found that, although greatly diminished, there was slow ppGpp degradation and growth resumption after a lag period, concomitant with decrease in ppGpp pool. …”
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9495
Image_1_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.TIF
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9496
Table_2_Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness.xlsx
Published 2020“…<p>There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. …”
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9497
Data_Sheet_1_Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance.pdf
Published 2019“…Remarkably, in S. coelicolor, a model Streptomyces species, topoisomerase I (TopA) is solely responsible for the removal of negative DNA supercoils. …”
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9498
Table_5_Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance.pdf
Published 2019“…Remarkably, in S. coelicolor, a model Streptomyces species, topoisomerase I (TopA) is solely responsible for the removal of negative DNA supercoils. …”
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9499
Table_3_Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance.xlsx
Published 2019“…Remarkably, in S. coelicolor, a model Streptomyces species, topoisomerase I (TopA) is solely responsible for the removal of negative DNA supercoils. …”
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9500
Table_4_Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance.xlsx
Published 2019“…Remarkably, in S. coelicolor, a model Streptomyces species, topoisomerase I (TopA) is solely responsible for the removal of negative DNA supercoils. …”