Image_1_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Although the cytokine release by CD19.CAR-T cells upon activation was not hampered by both COX-inhibitors, activation and proliferation of CAR-T cells were significantly inhibited via diminishing the NF-ĸB signaling pathway by a significant down-regulation of expression of CD27 on CD4⁺ and CD8⁺ CAR-T cells, followed by a clear decrease of phosphorylated NF-ĸB p65 in both CD4⁺ and CD8⁺ CAR-T cells by a factor of 1.8. …”

Table1_Pharmacokinetic Characteristics of Siponimod in Healthy Volunteers and Patients With Multiple Sclerosis: Analyses of Published Clinical Trials.pdf by Chen Chaoyang (12521026)

“…Fluconazole combination led to a decrease in CL/F (approximately 0.5 times) and an increase in AUC_0-∞/D (approximately 1.3 times).…”

<i>nowl</i> and <i>Nf1</i> interact in the regulation of sleep. by Gianna W. Maurer (6103637)

“…Additional effector line controls (<i>nowl-RNAi/+</i>, <i>Nf1-RNAi/+</i>, and <i>Nf1/+</i>) are shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008727#pgen.1008727.s008" target="_blank">S8 Fig</a> Genotypes that are indicated as different from the <i>elav>+</i> controls are also statistically different (P< 0.05) from controls shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008727#pgen.1008727.s008" target="_blank">S8 Fig</a> (D) Daily sleep profiles of double-knockdown male animals (<i>elav>Nf1-RNAi</i>, <i>nowl-RNAi</i>) display a pronounced decrease in sleep. …”

Role of DPAP3 in RBC invasion. by Christine Lehmann (207801)

“…Hoechst staining) showing a decrease in invasion of the A1cKO upon RAP treatment. …”

Table_1_Canine urothelial carcinoma: expression of Periostin in spontaneous canine urothelial carcinoma and its correlation with histological features.xlsx by Eleonora Brambilla (17399407)

“…In normal bladder tissue, as reported in humans, a thick and strongly positive belt of POSTN was visible, and in canine BUCs, stating that the expression is comparable with human benign as well as malignant bladder tissue, a general decrease in POSTN expression was observed except for a strongly labeled ring of POSTN observed around some neoplastic nodules infiltrating the muscle layer. …”

Toll signaling in the Drosophila larval fat body shifts programs of anabolic lipid metabolism and dysregulates nutrient storage by Brittany Martínez (8728753)

“…Expression of Toll^10b in the fat body leads to a tissue-autonomous decrease in triglyceride levels. …”

Adolescent CORT exposure regulates cortico-limbic trkB and ERK42/44 phosphorylation. by Elizabeth T. Barfield (4631341)

“…<p>(a) Based on our findings, we profiled the neurobiological effects of CORT in a mPFC–vHC–amygdala circuit. …”

ARQiv detection of modulations in Notch pathway signaling. by Steven L. Walker (189338)

“…Following pre-treatment scans at 48 hpf, DAPT treatments commenced and post-treatment scans were taken every 24 hrs thereafter until 120 hpf. The results show a concomitant decrease in Notch signaling with increasing DAPT concentration. …”

Table1_Multi-Scale Modeling Recapitulates the Effect of Genetic Alterations Associated With Diffuse Large B-Cell Lymphoma in the Germinal Center Dynamics.docx by Elena Merino Tejero (10102450)

“…Models with constitutive activation of the nuclear factor kappa-light-chain-enhancer of activated B-cell (NF-kB) pathway alone and in codominance or co-expression with the enforced BCL6 expression (IRF^inc and BCL^incIRF^inc) result in a decrease of GC B cells and unaltered PC production at early stages of the GC reaction, as observed experimentally. …”

Image_1_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…In mice with CIA, at day 35 there was a significant 39% (p < 0.042) decrease in the CDA in mice treated with C2-Crry. …”

<b>The moderating effect of financial literacy on risk preferences and time preferences</b> by Calvin Mudzingiri (22188109)

“…An increase in financial literacy is associated with a decrease in time preferences, indicating that as financial literacy rises, subjects become more patient. …”

Regional Outcome Evaluation Program (P.Re.Val.E.): Reduction of inequality in access to effective health care in the Lazio region of Italy (2012–2015) by Martina Ventura (5018948)

“…By comparing the adjusted proportions in patients with the highest education level (a university degree or higher) to those with the lowest level education level (None/Primary school), a decrease in the percentage difference was observed during the study period. …”

Smo ubiquitination is regulated by Hh and phosphorylation. by Ruohan Xia (188658)

“…(C) NIH3T3 cells were transfected with Myc-hSmo and treated with or without recombinant Shh. Shh induced a marked decrease in hSmo ubiquitination (lane 3). …”

Systematic Review of Screening and Surveillance Programs to Protect Workers from Nanomaterials by Mary Gulumian (668890)

“…Of these, six compared health indicators between exposed and unexposed workers and one study described a surveillance program. All studies were at a high risk of bias. …”

Data_Sheet_1_Introducing and Implementing HIV Self-Testing in Côte d'Ivoire, Mali, and Senegal: What Can We Learn From ATLAS Project Activity Reports in the Context of the COVID-19... by Arsène Kouassi Kra (11156478)

“…</p><p>Results: In all three countries, the pre-COVID-19 period was marked by a gradual increase in HIVST distribution. The period corresponding to the initial emergency response (March-May 2020) witnessed an important disruption of activities: a total suspension in Senegal, a significant decline in Côte d'Ivoire, and a less pronounced decrease in Mali. …”

AKMT is important for invasion and egress, but not for parasite replication. by Aoife T. Heaslip (207534)

“…(C) The loss of AKMT results in a ∼90% decrease in invasion efficiency. The number of invaded parasites per field was counted in 10 fields each in 3 independent experiments. ***: P value <0.0001 (D) <i>Top</i>: Outline of A23187 induced egress assay. …”

Image_3_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…In mice with CIA, at day 35 there was a significant 39% (p < 0.042) decrease in the CDA in mice treated with C2-Crry. …”

2-AA down-regulates the transcription of many genes involved in the translational capacity of the cell. by Yok-Ai Que (70055)

“…The ratio of translating polysomes to 70S was higher in the untreated cultures (left) than in the cultures grown in presence of exogenously added 2-AA (right) reflecting a decrease in translational activity. <b>F</b>. …”

Increased <i>Toll-1, wek</i> and <i>sarm</i> levels can induce cell loss in the absence of infection. by Deepanshu N. D. Singh (20721878)

“…<p><b>(A,B)</b> In the absence of infection, over-expression of activated <i>Toll-1</i>^<i>10b</i> in DANs (with <i>THGAL4; R58E02GAL4</i>) caused a rather mild and not significant decrease in PAMs. …”

Image_9_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Although the cytokine release by CD19.CAR-T cells upon activation was not hampered by both COX-inhibitors, activation and proliferation of CAR-T cells were significantly inhibited via diminishing the NF-ĸB signaling pathway by a significant down-regulation of expression of CD27 on CD4⁺ and CD8⁺ CAR-T cells, followed by a clear decrease of phosphorylated NF-ĸB p65 in both CD4⁺ and CD8⁺ CAR-T cells by a factor of 1.8. …”