Table_2_Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.XLSX by Marie Isabel Rasmussen (11110416)

“…There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019).…”

EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer - Fig 9 by Stephanie Rossnagl (553093)

“…<p><b>Myeloid cells are intrinsically different based on exposure to EDA-FN.</b> (A) Adoptive transfer using similar numbers of isolated CD11b⁺-cells from cKO and CT animals mixed with B16 melanoma cells and injected subcutaneously showed a significant decrease in growth in the tumors that contained cKO CD11b⁺-cells, <i>n</i> = 16/10/18/18. …”

Image_1_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_1_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_3_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_3_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Chronic High Fructose Intake Reduces Serum 1,25 (OH)₂D₃ Levels in Calcium-Sufficient Rodents by Veronique Douard (549533)

“…Replacing glucose with fructose prevented these increases in Ca²⁺ transporter, CYP27B1, and 1,25(OH)₂D₃ levels induced by a low Ca²⁺ diet. In adult mice fed for three mo a normal Ca²⁺ diet, renal expression of CYP27B1 and of CYP24A1 (24-hydroxylase) decreased and increased, respectively, when the carbohydrate source was fructose instead of glucose or starch. …”

Timeline of interventions and assessments. by Shirley Yen (12632685)

“…Skills to Enhance Positivity (STEP) is an acceptance-based intervention, designed to increase attention to, and awareness of, positive affect and positive experiences. Results from a pilot RCT demonstrated engagement of the target (positive affect) and a decrease in clinical outcomes (suicidal events; i.e., either a suicide attempt or an emergency intervention for an acute suicidal crisis), providing support to test the clinical effectiveness of STEP in a larger clinical trial with clinical staff implementing the intervention.…”

DataSheet_1_Differential regulatory T cell signature after recovery from mild COVID-19.pdf by Pedro Henrique de Sousa Palmeira (14758156)

“…Interestingly, Pool Spike CoV-2 elicited a decrease in Treg IL-17⁺ frequency in the Severe Recovered group. …”

Factor associated with neonatal mortality. by Sujan Kumar Naha (20577028)

“…Among them, 23.07% received a single dose, and 22.82% took adequate doses (receiving more than two doses) and adhered to WHO guidelines. …”

Table1_Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms... by Pei Teng Lum (16537509)

“…Further, a significant depletion in brain malondialdehyde (MDA) level, an increase in reduced glutathione (GSH) level, succinate dehydrogenase (SDH), superoxide dismutase (SOD) and catalase (CAT) activities, and a decrease in tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β) and interleukin-6 (IL-6) levels were observed in mangiferin treated groups. …”

Image_2_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

<b>IER3IP1 mutations cause neonatal diabetes due to impaired proinsulin trafficking</b> by Hossam Montaser (10017443)

“…While these mutant stem cell lines differentiated normally into definitive endoderm and pancreatic progenitors, we observed that IER3IP1-KO stem cell derived-islets (SC-islets) presented a significant decrease in beta cell numbers and elevated ER stress. …”

Screen candidates modify the expression of RAS/MAPK components. by Dariel Ashton-Beaucage (538989)

“…(D) Also in agreement with the qPCR data, a specific decrease in PTP-ER levels was observed upon depletion of <i>CG4936</i>.…”

PRDM9 binds in vitro to meiotic recombination hotspots. by Corinne Grey (200646)

“…The amount of signal due to binding of each probe to PRDM9^wm7 is shown (with standard error), relative to <i>Psmb9^TC</i>. The decrease of binding to the double mutant probe <i>Psmb9</i>^CT (0.07% binding relative to <i>Psmb9</i>^TC) is consistent with a cumulative effect of each single mutant (0.36% and 0.14% binding relative to <i>Psmb9</i>^TC) suggesting their effects are independent. …”

Differentially methylated regions interrogated for metastable epialleles associate with offspring adiposity by Stephanie W Waldrop (19653383)

“…</p> <p>DNAm of MEs has been suggested to play a role in energy balance and has previously been associated with obesity in adult and pediatric populations.…”

Data_Sheet_1_Fatigue Induced by Repeated Changes of Direction in Élite Female Football (Soccer) Players: Impact on Lower Limb Biomechanics and Implications for ACL Injury Preventio... by Matteo Zago (5721068)

“…Measures of exercise internal load were: peak post-exercise blood lactate concentration, heart rate (HR) and perceived exertion. Continuous linear correlations between kinematics/kinetics waveforms (during the ground contact phase of the pivoting limb) and the number of consecutive CoD were computed during the exercise using a Statistical Parametric Mapping (SPM) approach.…”

Image 1_Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway.tif by Lu Liu (171341)

“…Background<p>Epimedium brevicornu: Maxim., a traditional Chinese botanical drug, has shown significant therapeutic effects against hepatocellular carcinoma (HCC), with its flavonoid compounds exhibiting anti-HCC activity through various mechanisms. …”

DataSheet1_Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation... by Eldiza Puji Rahmi (8584506)

“…In the XO inhibitory activity, none of the samples exhibited greater than 50% inhibition. However, in a rat model, EtOH80 extract (200 mg/kg/day) and andrographolide (30 mg/kg/day) decreased serum uric acid levels and reduced liver XO activity, reduced the protein expression levels of URAT1 and GLUT9, and restored the decrease in OAT1 levels. …”

Developmental effects of auxin in the <i>M</i>. <i>polymorpha</i> thallus. by Eduardo Flores-Sandoval (746468)

“…<b>(L)</b> Ventral side of wild-type thallus grown on 100 μM L-Kyn; a decrease in rhizoid number exposes ventral scales. …”