Weight and histopathological analyses of WT and homozygous VCP^R155H/R155H mice. by Angèle Nalbandian (131106)

“…<p>(A) VCP^R155H/R155H mice are much smaller and weaker and demonstrate gross abnormalities such as hairless areas with ichthyosis-like thickening of the superficial layers of the skin compared to their WT littermates at day 14. …”

Recording of Influenza-Like Illness in UK Primary Care 1995-2013: Cohort Study by Pia Hardelid (355911)

“…<div><p>Background</p><p>There is a lack of recent studies examining recording of influenza-like illness (ILI) in primary care in the UK over time and according to population characteristics. …”

Dynamic and Cell-Infiltratable Hydrogels as Injectable Carrier of Therapeutic Cells and Drugs for Treating Challenging Bone Defects by Qian Feng (302178)

“…We believe that this is the first demonstration on applying injectable hydrogels as effective carriers of therapeutic cargo for treating dysfunctions in deep and enclosed anatomical sites via a minimally invasive procedure.…”

Mammalian herbivore movement into drought refugia has cascading effects on savanna insect communities. by Matthew Trisos (9256332)

“…Grasshopper abundance decreased at droughted Skukuza both on and off mounds but decreased on mounds and increased off mounds at non-droughted Pretoriuskop. …”

Data_Sheet_1_Non-dipping pulse rate and chronic changes of the kidney in patients with chronic kidney disease.docx by Rina Oba (14648237)

“…Patients with non-dipping PR were older and had worse kidney function, higher blood pressure, greater prevalence of dyslipidemia, lower hemoglobin levels, and a larger amount of urinary protein excretion than patients with dipping PR. …”

Neoadjuvant breast cancer treatment response; tumor size evaluation through different conventional imaging modalities in the NeoDense study by Ida Skarping (8203665)

“…We investigated the agreement of tumor size by the different imaging modalities, and their accuracy of tumor size estimation. Patients with a radiological complete response or radiological partial response (≥30% decrease in tumor diameter) during NACT were classified as radiological early responders.…”

Data_Sheet_2_Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling... by Shengwei Chen (1764178)

Transport and instream removal of the <i>Cry1Ab</i> protein from genetically engineered maize is mediated by biofilms in experimental streams by Arial J. Shogren (5562782)

“…Overall, <i>Cry1Ab</i> uptake was strongly predicted by measures of biofilm accumulation, including algal chlorophyll <i>a</i> and percent cover of filamentous algae. Average <i>Cry1Ab</i> uptake velocity (v_f = 0.059 ± 0.009 mm s^-1) was comparable to previously reported uptake of labile dissolved organic carbon (DOC; mean v_f = 0.04 ± 0.008 mm s^-1). …”

Feeding of ambroxol ameliorates neurodevelopmental defects and ER stress in the mutated hGBA induced <i>Drosophila</i> eye. by Takahiro Suzuki (88656)

“…<p>Ambroxol can recover morphological defects and decrease ER stress in transgenic flies. (A) Less fluorescence emitted by the eye imaginal discs of hGBA^RecNciI transgenic combinations treated with, than without 1 mM Ambroxol. …”

Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkable weight bearing and paw withdrawal threshold decrease, alterations in the tibial and femoral structures (decreased trabeculation and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining, disrupted tidemark integrity, synovial hyperplasia, and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord.…”

Process of Cu release quantification. by Andrea Timoncini (20390373)

“…The main aim of this study is to investigate the impact of accelerated ageing, mimicking a high-touch frequency by cyclic exposure to artificial sweat solution as well as to temperature and relative humidity variations, on the efficacy of Cu-based thin foils against <i>P</i>. …”

Data_Sheet_4_Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment.ZIP by Faqi Wang (2072857)

“…This study adds to the evidence that LIFUS could become a promising and non-invasive treatment strategy for the clinical treatment of central nervous system diseases related to cognitive impairments in the future.…”

Effects of Maternal Diet and Exercise during Pregnancy on Glucose Metabolism in Skeletal Muscle and Fat of Weanling Rats by Mukesh Raipuria (718705)

“…Half underwent voluntary exercise (CE/FE) with a running wheel introduced 10 days prior to mating and available until the dams delivered; others remained sedentary (CS/FS). …”

Data_Sheet_1_Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment.xlsx by Faqi Wang (2072857)

“…This study adds to the evidence that LIFUS could become a promising and non-invasive treatment strategy for the clinical treatment of central nervous system diseases related to cognitive impairments in the future.…”

Table_1_Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microsco... by Paula Dlugosz (6400175)

“…Details of this pathway are still not fully understood since the participating components are highly variable and create a complex mixture of interacting molecules. Reelin is proteolytically processed resulting in five different fragments some of which carrying the binding site for two different but highly homologous receptors, apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR). …”

Calcineurin/NFAT Signaling Represses Genes <i>Vamp1</i> and <i>Vamp2</i> via PMCA-Dependent Mechanism during Dopamine Secretion by Pheochromocytoma Cells by Michalina Kosiorek (542406)

“…</p><p>Results</p><p>PMCA2- and PMCA3-deficient cells displayed profound decrease in dopamine secretion accompanied by a permanent increase in [Ca²⁺]_c. …”

Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Specific Clock Genes in the Mouse Cerebral Cortex by Valérie Mongrain (199819)

“…Indeed, mutations in some clock genes modify the markers of sleep homeostasis and an increase in homeostatic sleep drive alters clock gene expression in the forebrain. Here, we investigate a possible mechanism by which sleep deprivation (SD) could alter clock gene expression by quantifying DNA-binding of the core-clock transcription factors CLOCK, NPAS2, and BMAL1 to the <em>cis</em>-regulatory sequences of target clock genes in mice. …”

S1 File - by Andrea Timoncini (20390373)

“…The main aim of this study is to investigate the impact of accelerated ageing, mimicking a high-touch frequency by cyclic exposure to artificial sweat solution as well as to temperature and relative humidity variations, on the efficacy of Cu-based thin foils against <i>P</i>. …”

Table_1_Evaluating the Migration Mortality Hypothesis Using Monarch Tagging Data.docx by Orley R. Taylor (4249228)

“…Thus, the main determinant of yearly variation in overwintering population size is summer population size with migration success being a minor determinant. Consequently, increasing milkweed habitat, which has the potential of increasing the summer monarch population, is the conservation measure that will have the greatest impact.…”

Data_Sheet_1_Diet, Immunity, and Microbiota Interactions: An Integrative Analysis of the Intestine Transcriptional Response and Microbiota Modulation in Gilthead Seabream (Sparus a... by Joana P. Firmino (10097098)

“…In the present study, the modulation of the transcriptional immune response (microarray analysis) and microbiota [16S Ribosomal RNA (rRNA) sequencing] in the intestine of the euryhaline fish gilthead seabream (Sparus aurata) fed a dietary supplementation of garlic, carvacrol, and thymol EOs was evaluated. …”