DataSheet_1_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

Boxplot of the RA group after batch correction. by Chang-sheng Liao (18591969)

“…<div><p>Objective</p><p>To elucidate potential molecular mechanisms differentiating osteoarthritis (OA) and rheumatoid arthritis (RA) through a bioinformatics analysis of differentially expressed genes (DEGs) in patient synovial cells, aiming to provide new insights for clinical treatment strategies.…”

4-methylthiobutyl isothiocyanate synergize the antiproliferative and pro-apoptotic effects of paclitaxel in human breast cancer cells by Harneetpal Kaur (13973217)

“…In western blot experiment, the combination had a significant decrease in Bcl-xl protein level, whereas a higher level of p53, cleaved caspase-3, and cleaved caspase-9 proteins compared to individual treatment in <i>T</i>-47D cells. …”

Table_1_Neutrophil Extracellular Traps in SARS-CoV2 Related Pneumonia in ICU Patients: The NETCOV2 Study.DOCX by Mathieu Godement (10180910)

“…<p>Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a poorly understood disease involving a high inflammatory status. …”

DataSheet_3_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

Temporal trends in Human T-Lymphotropic virus 1 (HTLV-1) associated myelopathy/tropical spastic paraparesis (HAM/TSP) incidence in Martinique over 25 years (1986-2010) by Stephane Olindo (4976189)

“…Between 1996–2000 and 2011–2015 study periods, the HTLV-1 seroprevalence significantly decreased by 63%.</p><p>Conclusion</p><p>Martinique faces a sudden and rapid decline of HAM/TSP incidence from 2001 in comparison to 1986–2000 periods. …”

Data_Sheet_1_Fully Integrated PET/MR Imaging for the Assessment of the Relationship Between Functional Connectivity and Glucose Metabolic Rate.PDF by Lalith Kumar Shiyam Sundar (8622243)

“…Discussion: Measurement of functional connectivity within established brain networks did not provide a means to decrease the inter- or intrasubject variability of CMRGlc values. …”

Image_3_Endocannabinoid signaling regulates post-operative delirium through glutamatergic mediodorsal thalamus-prelimbic prefrontal cortical projection.TIF by Yang Liu (4829)

“…Background<p>Post-operative delirium (POD), a common post-operative complication that affects up to 73. 5% of surgical patients, could prolong hospital stays, triple mortality rates, cause long-term cognitive decline and dementia, and boost medical expenses. …”

The role of TCTP and CSN4 in the control of CULLIN neddylation and cell proliferation is conserved in <i>Drosophila</i>. by Léo Betsch (6273707)

“…<b>(g)</b> Impaired larval development is associated with a decrease of the CUL1^NEDD8 abundance in the <i>tub</i>><i>dTCTPi</i> compared to <i>tub</i>-GAL4. …”

Genetic screen in haploid ESCs for PMP resistance identifies Anoikis modulators. by Giulio Di Minin (4768200)

“…<p><b>(A)</b> Model of the activity of known SMO targeting compounds. …”

The Effect of Probiotic Treatment on Patients Infected with the H7N9 Influenza Virus by Xinjun Hu (412383)

“…<div><p>Background</p><p>A novel avian-origin influenza A (H7N9) virus emerged and spread among humans in Eastern China in 2013. …”

Table_1_The effect of C–C motif chemokine ligand 2 supplementation on in vitro maturation of porcine cumulus-oocyte complexes and subsequent developmental competence after partheno... by Sohee Kim (740141)

“…All CCL2-treatment groups showed a significant increase in intracellular glutathione levels and a significant decrease in reactive oxygen species levels, compared to the control. …”

DataSheet_2_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

TAL1 associates with the <i>FUBP1</i> promoter via the <i>GATA</i> element to activate <i>FUBP1</i> expression. by Marlene Steiner (6240392)

“…Mutations in the GATA-motif (white bars 8 (M1), 9 (M2)) but not in the E-box (grey bars 6 (M1), 7 (M2)) led to a significant decrease of luciferase activity (P values are indicated). …”

Table_1_Multi-Domain Touchscreen-Based Cognitive Assessment of C57BL/6J Female Mice Shows Whole-Body Exposure to 56Fe Particle Space Radiation in Maturity Improves Discrimination L... by Ivan Soler (11545819)

“…Most preclinical studies with mature, “astronaut-aged” rodents suggest space radiation diminishes performance in classical hippocampal- and prefrontal cortex-dependent tasks. However, a rodent cognitive touchscreen battery unexpectedly revealed ⁵⁶Fe radiation improves the performance of C57BL/6J male mice in a hippocampal-dependent task (discrimination learning) without changing performance in a striatal-dependent task (rule-based learning). …”

Als acts downstream of GSK3β and upstream of SCF/Slimb/βTRCP E3 Ub ligase. by Gerlinde Reim (654594)

“…Combined <i>als</i> and <i>ter94</i> depletion caused an elevation of <i>wf</i> (lane 2) or a decrease of <i>arr</i> (lane 5). No alteration was observed for the Hh target gene <i>ptc</i> (lanes 7–9). …”

Boxplot of the OA group after batch correction. by Chang-sheng Liao (18591969)

“…<div><p>Objective</p><p>To elucidate potential molecular mechanisms differentiating osteoarthritis (OA) and rheumatoid arthritis (RA) through a bioinformatics analysis of differentially expressed genes (DEGs) in patient synovial cells, aiming to provide new insights for clinical treatment strategies.…”

pone.0331193.t003 - by Carol Kotliar (22351525)

“…The global cognitive score increased by 4.6 points (5%) in the intervention group compared to a decrease of 0.5 points in the control group (p < 0.001). …”

Systemic antioxidant treatment and intermittent fasting delay axonal degeneration in mice. by Andrea Calixto (16070)

“…The neurofilament signal decrease progressively at 3, 5 and 7 days after nerve injury in non-treated mice (A). …”

Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals by Hlengiwe Pretty Madlala (750105)

“…</p><p>Novelty of the Work</p><p>The results of this study are novel in that they show 1) a correlation between blood pressure reduction and increased urinary Na⁺ excretion by OA, 2) a more marked MAP reduction in hypertensive animals and 3) a drug-induced decrease in proximal tubule Na⁺ reabsorption. …”