Data_Sheet_1_Inhibiting methanogenesis by targeting thermodynamics and enzymatic reactions in mixed cultures of rumen microbes in vitro.PDF by Kairi Tanaka (19418200)

“…Here, we provide a proof of concept that the combination of an electron acceptor and a methane analog may be exploited to improve microbial efficiency via methanogenesis inhibition.…”

Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication by Jun Li (6494)

“…<div><p>In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous bupivacaine, followed by an intravenous injection of adrenalin or isoprenalin, and the electrocardiogram (ECG), left ventricular systolic pressure (LVSP), left ventricular end-diastolic pressure (LVEDP), the maximum rate of rise of left ventricular pressure (+dP/dtmax) and the maximum rate of pressure decrease (-dP/dtmax) were continually monitored. …”

Determinant of Selective Removal (DSR) sequences can reduce protein levels expressed from P<i>_urg1lox</i>. by Adam T. Watson (500083)

“…<p>(<b>A</b>). Schematic of the P<i>_urg1lox</i> locus following RCME to introduce yEGFP under the control of the <i>urg1</i> promoter. …”

Image_2_Analysis of the Characteristics of TIGIT-Expressing CD3−CD56+NK Cells in Controlling Different Stages of HIV-1 Infection.tif by Xin Zhang (35492)

“…In both HIV-1-infected individuals and healthy donors, TIGIT was predominantly expressed in NKG2A⁻NKG2C⁺NK cells, with a significantly higher proportion than in NKG2A⁺NKG2C⁻NK cells. …”

Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in mice by Katsutaka Oishi (278169)

“…The DF-induced increases in body weight gain, food efficiency, adipose tissue mass, lipogenic gene expression in metabolic tissues, and hepatic lipid accumulation were abolished in <i>db</i>/<i>db</i> mice, suggesting that the leptin resistance is a cause of DF-induced metabolic disorders. DF resulted in deep hypothermia in <i>db</i>/<i>db</i>, as well as in wild-type mice, suggesting that a decrease in energy expenditure was not the main cause of DF-induced obesity. …”

Genome-wide genic copy numbers for nine Macaca species based on 1kb windows by Jing Li (7426562)

“…Unplaced contigs were merged as ‘chrUn’ in data processing to decrease the CPU time.</p><p> </p><p>Bolger AM, Lohse M, Usadel B (2014) Trimmomatic: a flexible trimmer for Illumina sequence data. …”

<i>Dpp</i> expression increases after inducing apoptosis in eye discs. by Sergio B. Velarde (11261991)

“…(C–C”” and F-F””) Higher magnification images corresponding to the regions highlighted by white rectangles on the panels B (C–C””) and E (F-F””). (A–B”) In control eye discs, Dpp is expressed in a band of cells just anterior to the MF, and its expression levels decrease abruptly to a homogeneous low level behind the furrow. …”

Rae1 regulates proliferation in <i>Drosophila</i> and in mammalian cells. by Maryam Jahanshahi (474646)

“…<p>(A-A’) Clones undergoing constitutive <i>Rae1</i> RNAi (green in A, tracing in A’) show reduced BrdU incorporation (red) compared to adjacent tissue. …”

ERα binds to the <i>DEK</i> promoter in response to 17β-estradiol exposure and receptor activity correlates with <i>DEK</i> expression. by Lisa M. Privette Vinnedge (128459)

“…(B) Treatment with 3 µg/ml tamoxifen results in a dramatic decrease in <i>DEK</i> expression. Quantitative RT-PCR was performed to detect <i>DEK</i> expression in MCF7 cells grown in low serum treated with 3 µg/ml tamoxifien during the time course shown. …”

Pathways identified by IPA connects Bacopa to memory, neuroprotection and AD. by How-Wing Leung (4385896)

“…Explanation of the numbered connections: (1) ATF4 and NRF2 functionally interact with each other [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref040" target="_blank">40</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref043" target="_blank">43</a>]. (2) ATF4 is implicated in memory [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref059" target="_blank">59</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref062" target="_blank">62</a>]. (3) NRF is implicated in memory [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref063" target="_blank">63</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref067" target="_blank">67</a>]. (4) Translation initiation factor eIF2-alpha stimulates translation of ATF4 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref068" target="_blank">68</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref071" target="_blank">71</a>]. (5) eIF2-alpha is implicated in memory formation [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref072" target="_blank">72</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref073" target="_blank">73</a>]. (6) ATF4 has been implicated in Alzheimer’s disease (AD) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref074" target="_blank">74</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref078" target="_blank">78</a>]. (7) NRF2 has also been linked to AD [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref063" target="_blank">63</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref065" target="_blank">65</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref067" target="_blank">67</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref079" target="_blank">79</a>]. (8) NRF2 plays a critical role in neuroprotection [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref080" target="_blank">80</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref083" target="_blank">83</a>]. (9) FOXO3 mediates oxidative stress-induced neuronal cell death [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref084" target="_blank">84</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref087" target="_blank">87</a>]. …”

Data from: Does green stem photosynthesis affect plant drought tolerance and recovery in avocado? by Gregory Goldsmith (22088747)

“…However, we observed an increase in hydraulic conductivity during the drought period with an increase in the concentration of sugars in the sapwood and a decrease in the concentration of starch, suggesting osmotic adjustment. nulltheless, the contribution of carbon gain through stem photosynthesis may not play a significant role in hydraulic functioning of avocado under these conditions.…”

Table 1_Effects of lidocaine-plus-meloxicam treatment on behavioral and physiological changes, and leukocyte heat shock protein 90 gene expression after surgical castration in Hanw... by Ingu Cho (20381409)

“…Surgical castration was performed with a Newberry knife and a Henderson castration tool. …”

Copper(II) Complexes of Halogenated Quinoline Schiff Base Derivatives Enabled Cancer Therapy through Glutathione-Assisted Chemodynamic Therapy and Inhibition of Autophagy Flux by Wen-Ying Shen (12208897)

“…Moreover, <b>Cu­(L¹⁰)₂</b> showed higher antitumor activity and a better safety profile than the CDT agent <b>Cu1</b>. …”

Image_5_Microbial, Physical, and Chemical Changes in Galveston Bay Following an Extreme Flooding Event, Hurricane Harvey.TIF by Jamie L. Steichen (8747481)

“…The floodwaters delivered a significant influx of dissolved organic carbon (DOC), organic pollutants and nutrients along with terrestrial and freshwater associated microbes. …”

S4 File - by Patricia Volkow (772718)

“…Non-severe-IRIS-KS was defined as: an increase in the number of lesions plus a decrease of ≥one log10 HIV-VL, or an increase of ≥50cells/mm3 or ≥2-fold in baseline CD4+cells. …”

The AL-1-activated ERK1/2 and AKT1 signaling pathways were involved in the anti-H₂O₂-induced cell cytotoxicity of AL-1. by Guang-Rong Yan (418185)

“…<p>(A) The phosphorylation levels of ERK1/2 and AKT1 were upregulated by AL-1 in a dose-dependent manner, with total ERK1/2 and AKT1 levels remaining unchanged. …”

Image_3_Comparative transcriptome analysis of purple-fleshed sweet potato and its yellow-fleshed mutant provides insight into the transcription factors involved in anthocyanin bios... by Wen Dong (467988)

“…By analyzing the IbMYB1 genotype in ZZ^P and XL^Y, we found that the IbMYB1-2, a MYB TF involved in anthocyanin biosynthesis, was missing in the XL^Y genome, which might lead to an extreme decrease in anthocyanins in XL^Y. …”

Crystal Structure and Thermoelectric Properties of Novel Quaternary Cu₂MHf₃S₈ (MMn, Fe, Co, and Ni) Thiospinels with Low Thermal Conductivity by Oleksandr Cherniushok (10075227)

“…As it was evaluated from the Callaway approach and confirmed by the speed of sound measurements, such a crystal structure promotes the increase in lattice anharmonicity, which is the main reason for the low κ_lat. …”

Table_3_Comparative transcriptome analysis of purple-fleshed sweet potato and its yellow-fleshed mutant provides insight into the transcription factors involved in anthocyanin bios... by Wen Dong (467988)

“…By analyzing the IbMYB1 genotype in ZZ^P and XL^Y, we found that the IbMYB1-2, a MYB TF involved in anthocyanin biosynthesis, was missing in the XL^Y genome, which might lead to an extreme decrease in anthocyanins in XL^Y. …”

Image_3_Microbial, Physical, and Chemical Changes in Galveston Bay Following an Extreme Flooding Event, Hurricane Harvey.TIF by Jamie L. Steichen (8747481)

“…The floodwaters delivered a significant influx of dissolved organic carbon (DOC), organic pollutants and nutrients along with terrestrial and freshwater associated microbes. …”