Data_Sheet_1_Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Mediated by Rac1 Glucosylation.doc by Conceição S. Martins (9314015)

“…We assessed Wnt signaling activation in vitro with TOP/FOPflash luciferase assays, determined nuclear β-catenin translocation by immunofluorescence, measured cyclin D1 protein expression by Western blotting, and quantified cell proliferation by Ki67 immunostaining. In vivo, TcdA decreased β-catenin, cyclin D1, and cMYC expression and inhibited the translocation of β-catenin into the nucleus in the ileum epithelial cells. …”

Data Sheet 1_Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.zip by Qiwei Zhao (12519351)

“…Moreover, CAP inhibited glutamate release while enhancing BECN1-SLC7A11 binding, suggesting a reduction in SLC7A11 activity through the AMPK/BECN1 pathway. …”

Intake of Vitamin and Mineral Supplements and Longitudinal Association with HbA_1c Levels in the General Non-Diabetic Population—Results from the MONICA/KORA S3/F3 Study... by Sigrid Schwab (814972)

“…<div><p>Background</p><p>Lower levels of hemoglobin A_1c (HbA_1c) are associated with a decreased risk of cardiovascular complications in diabetic and non-diabetic individuals. …”

Influence of baseline preferences on the implicit measures (spatial indices of mouse kinematics). by Cinzia Calluso (5662420)

Image_2_Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy.jpeg by FNU Deepika (11881310)

“…Men with T ≥ 264 ng/dl showed significant decreases in HbA1c at 12 months (−3.1 ± 9.2 vs. 3.2 ± 13.9%; p = 0.005), fasting glucose at 18 months (−4.2 ± 31.9 vs. 13.0 ± 57.3%; p = 0.040), LDL at 6 months (−6.4 ± 27.5 vs. 12.8 ± 44.1%; p = 0.034), and leptin at 18 months (−40.2 ± 35.1 vs. −27.6 ± 31.0%; p = 0.034) compared to those with T < 264 ng/dl. …”

Image_1_Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy.jpeg by FNU Deepika (11881310)

“…Men with T ≥ 264 ng/dl showed significant decreases in HbA1c at 12 months (−3.1 ± 9.2 vs. 3.2 ± 13.9%; p = 0.005), fasting glucose at 18 months (−4.2 ± 31.9 vs. 13.0 ± 57.3%; p = 0.040), LDL at 6 months (−6.4 ± 27.5 vs. 12.8 ± 44.1%; p = 0.034), and leptin at 18 months (−40.2 ± 35.1 vs. −27.6 ± 31.0%; p = 0.034) compared to those with T < 264 ng/dl. …”

Table_1_Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy.docx by FNU Deepika (11881310)

“…Men with T ≥ 264 ng/dl showed significant decreases in HbA1c at 12 months (−3.1 ± 9.2 vs. 3.2 ± 13.9%; p = 0.005), fasting glucose at 18 months (−4.2 ± 31.9 vs. 13.0 ± 57.3%; p = 0.040), LDL at 6 months (−6.4 ± 27.5 vs. 12.8 ± 44.1%; p = 0.034), and leptin at 18 months (−40.2 ± 35.1 vs. −27.6 ± 31.0%; p = 0.034) compared to those with T < 264 ng/dl. …”

Image 4_Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.tif by Jiawei Sun (772107)

“…Objective<p>To investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades.…”

Image 6_Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.tif by Jiawei Sun (772107)

“…Objective<p>To investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades.…”

Image 5_Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.tif by Jiawei Sun (772107)

“…Objective<p>To investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades.…”

Image 1_Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.tif by Jiawei Sun (772107)

“…Objective<p>To investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades.…”

Image 3_Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.tif by Jiawei Sun (772107)

“…Objective<p>To investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades.…”

Image 2_Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.tif by Jiawei Sun (772107)

“…Objective<p>To investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades.…”

C2GnT1 gene knockdown decreases C2-O-sLe^X glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

“…<p>(A) C2GnT1 suppression by shRNA resulted in decreased mRNA levels of C2GnT1 but not FucT-III in LS174T cells, (scrambled shRNA vector, lane 1, and C2GnT1 shRNA vector, lane 2). …”

Data_Sheet_1_Marathon Running Increases Synthesis and Decreases Catabolism of Joint Cartilage Type II Collagen Accompanied by High-Energy Demands and an Inflamatory Reaction.PDF by José A. Hernández-Hermoso (11545663)

“…Accompanied by an increase in type II collagen cartilage fibrils synthesis (sPIINP increase) and a decrease in its catabolism (sC2C decrease), without changes in non-collagenous cartilage metabolism (sCOMP, sC846, and sYKL-40). …”

Secondary Hypervalent I(III)···O Interactions:  Synthesis and Structure of Hypervalent Complexes of Diphenyl-λ³-iodanes with 18-Crown-6 by Masahito Ochiai (2156452)

“…Substitution of an electron-withdrawing group onto the <i>para</i> position of Ph₂IBF₄ tends to increase in the complex stability. A linear Hammett relationship (ρ = 0.59) between log <i>K</i>_a and σ_p⁺ values of substituents indicates that the diaryl-λ³-iodanes with electropositive iodine(III) interact more efficiently with 18C6. …”

Secondary Hypervalent I(III)···O Interactions:  Synthesis and Structure of Hypervalent Complexes of Diphenyl-λ³-iodanes with 18-Crown-6 by Masahito Ochiai (2156452)

“…Substitution of an electron-withdrawing group onto the <i>para</i> position of Ph₂IBF₄ tends to increase in the complex stability. A linear Hammett relationship (ρ = 0.59) between log <i>K</i>_a and σ_p⁺ values of substituents indicates that the diaryl-λ³-iodanes with electropositive iodine(III) interact more efficiently with 18C6. …”

Secondary Hypervalent I(III)···O Interactions:  Synthesis and Structure of Hypervalent Complexes of Diphenyl-λ³-iodanes with 18-Crown-6 by Masahito Ochiai (2156452)

“…Substitution of an electron-withdrawing group onto the <i>para</i> position of Ph₂IBF₄ tends to increase in the complex stability. A linear Hammett relationship (ρ = 0.59) between log <i>K</i>_a and σ_p⁺ values of substituents indicates that the diaryl-λ³-iodanes with electropositive iodine(III) interact more efficiently with 18C6. …”

Secondary Hypervalent I(III)···O Interactions:  Synthesis and Structure of Hypervalent Complexes of Diphenyl-λ³-iodanes with 18-Crown-6 by Masahito Ochiai (2156452)

“…Substitution of an electron-withdrawing group onto the <i>para</i> position of Ph₂IBF₄ tends to increase in the complex stability. A linear Hammett relationship (ρ = 0.59) between log <i>K</i>_a and σ_p⁺ values of substituents indicates that the diaryl-λ³-iodanes with electropositive iodine(III) interact more efficiently with 18C6. …”

Characterization of optogenetically-evoked DA dynamics as a square wave dip. by Hidetoshi Urakubo (578508)