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143601
Sigma-1 receptors stabilize IRE1.
Published 2013“…<p>(a) Sig-1R knockdown decreases phosphorylated IRE1 (pIRE1) in various types of cells when cells are under ER stress. …”
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143602
Data_Sheet_1_Notoginsenoside Fc ameliorates renal tubular injury and mitochondrial damage in acetaminophen-induced acute kidney injury partly by regulating SIRT3/SOD2 pathway.docx
Published 2023“…Notoginsenoside Fc (Fc), a new saponin isolated from Panax notoginseng, exhibited numerous pharmacological actions. …”
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143603
Table1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.docx
Published 2025“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkable weight bearing and paw withdrawal threshold decrease, alterations in the tibial and femoral structures (decreased trabeculation and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining, disrupted tidemark integrity, synovial hyperplasia, and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord.…”
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143604
Effect of 1,25(OH)<sub>2</sub>D3 on the production of KIM-1 and fibronectin 1 from HRPTEpiC induced by recombinant human IL-17 (rhIL-17), human TNF- α or TGF-beta.
Published 2017“…<p><b>(A)</b> The expression of KIM-1 by HRPTEpiC was pretreated with 1,25(OH)<sub>2</sub>D3 (10 nM) as indicated, and then cultured for 24 hours with TNF-α (50 ng/mL) and/or IL-17 (50ng/mL) (n = 3). …”
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143605
Table_8_Rumen and fecal microbiomes are related to diet and production traits in Bos indicus beef cattle.XLSX
Published 2023“…Background<p>Ruminants harbor a complex microbial community within their gastrointestinal tract, which plays major roles in their health and physiology. …”
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143606
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143607
Data_Sheet_1_Acidification and hypoxia drive physiological trade-offs in oysters and partial loss of nutrient cycling capacity in oyster holobiont.PDF
Published 2023“…Introduction<p>Reef building oysters provide vast ecological benefits and ecosystem services. A large part of their role in driving ecological processes is mediated by the microbial communities that are associated with the oysters; together forming the oyster holobiont. …”
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143608
Supplementary Material for: Upstream stimulating factor 2 aggravates neuropathic pain induced in spinal nerve ligation-induced mice via regulating SNHG5/miR-181b-5p
Published 2024“…Therefore, USF2/SNHG5/miR-181b-5p/CXCL5 might be a promising target for neuropathic pain. However, the effect of USF2/SNHG5/miR-181b-5p/CXCL5 on neuropathic pain should also be investigated in further research.…”
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143609
Table_6_Transcriptome Profiling of the Elongating Internode of Cotton (Gossypium hirsutum L.) Seedlings in Response to Mepiquat Chloride.xlsx
Published 2020“…In summary, we confirmed the important role of GA in MC-induced growth inhibition of cotton, and further found that other hormones were also involved in this process in a GA-dependent manner. This study provides novel insights into the molecular mechanism underlying the MC-mediated inhibition of internode elongation in cotton seedlings.…”
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143610
Table_8_Transcriptome Profiling of the Elongating Internode of Cotton (Gossypium hirsutum L.) Seedlings in Response to Mepiquat Chloride.xlsx
Published 2020“…In summary, we confirmed the important role of GA in MC-induced growth inhibition of cotton, and further found that other hormones were also involved in this process in a GA-dependent manner. This study provides novel insights into the molecular mechanism underlying the MC-mediated inhibition of internode elongation in cotton seedlings.…”
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143611
Table_1_The moderating role of the late positive potential in the link between attachment anxiety and emotion regulation difficulties.DOCX
Published 2024“…</p>Methods<p>Brain activity was recorded using EEG from n = 63 adults while they performed a task in which they were instructed to either reappraise or suppress emotions elicited by unpleasant images. …”
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143612
Image_3_Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microsco...
Published 2019“…Details of this pathway are still not fully understood since the participating components are highly variable and create a complex mixture of interacting molecules. Reelin is proteolytically processed resulting in five different fragments some of which carrying the binding site for two different but highly homologous receptors, apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR). …”
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143613
Image_3_Rumen and fecal microbiomes are related to diet and production traits in Bos indicus beef cattle.pdf
Published 2023“…Background<p>Ruminants harbor a complex microbial community within their gastrointestinal tract, which plays major roles in their health and physiology. …”
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143614
Table_4_Weaning Induces Stress-Dependent DNA Methylation and Transcriptional Changes in Piglet PBMCs.XLSX
Published 2021“…We observed post-weaning hypermethylation of the glucocorticoid receptor (NR3C1) promoter and a significant decrease in NR3C1 expression (n = 9, p = 6.1 × 10<sup>–3</sup>). …”
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143615
DataSheet_2_Jieduquyuziyin Prescription Suppresses Inflammatory Activity of MRL/lpr Mice and Their Bone Marrow-Derived Macrophages via Inhibiting Expression of IRAK1-NF-κB Signalin...
Published 2020“…These results demonstrated that JP could inhibit the inflammatory activity of MRL/lpr mice and their BMDMs by suppressing the activation of IRAK1-NF-κB signaling and was supposed to be a good choice for the treatment of SLE.</p>…”
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143616
Table_4_Rumen and fecal microbiomes are related to diet and production traits in Bos indicus beef cattle.XLSX
Published 2023“…Background<p>Ruminants harbor a complex microbial community within their gastrointestinal tract, which plays major roles in their health and physiology. …”
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143617
vRNA in brain regions controlling cognitive function and within CNS border tissues.
Published 2023“…<p><b>(A)</b> Acute 251 cohort (n = 4) assessed<b>. (B)</b> SIV vRNA (<b>C)</b> SIV vDNA (copies/10^6 cells) in brain regions specified (RT-qPCR on post-mortem punch biopsies from specified regions. …”
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143618
How Similar Are the Mice to Men? Between-Species Comparison of Left Ventricular Mechanics Using Strain Imaging
Published 2012“…<div><h3>Background</h3><p>While mammalian heart size maintains constant proportion to whole body size, scaling of left ventricular (LV) function parameters shows a more complex scaling pattern. We used 2-D speckle tracking strain imaging to determine whether LV myocardial strains and strain rates scale to heart size.…”
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143619
Image_6_Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment.TIF
Published 2022“…This study adds to the evidence that LIFUS could become a promising and non-invasive treatment strategy for the clinical treatment of central nervous system diseases related to cognitive impairments in the future.…”
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143620
Table_2_Evaluating the Migration Mortality Hypothesis Using Monarch Tagging Data.docx
Published 2020“…Thus, the main determinant of yearly variation in overwintering population size is summer population size with migration success being a minor determinant. Consequently, increasing milkweed habitat, which has the potential of increasing the summer monarch population, is the conservation measure that will have the greatest impact.…”