Integrated analysis of promoter mutation, methylation and expression of <i>AKT1</i> gene in Chinese breast cancer patients by Jianfu Heng (3842491)

“…In clinicopathological factor analysis, <i>AKT1</i> showed significant hypo-methylation (<i>P</i> = 0.0249) and suppressed expression (<i>P</i> = 0.0375) in HER2 negative subtype. And a trend of decrease in expression level (<i>P</i> = 0.0624) of <i>AKT1</i> in the ER negative subtype was observed, which is significantly decreased in basal-like breast tumor (<i>P</i> = 0.0328).…”

Data_Sheet_1_Aldosterone-Induced Sarco/Endoplasmic Reticulum Ca2+ Pump Upregulation Counterbalances Cav1.2-Mediated Ca2+ Influx in Mesenteric Arteries.docx by Rogelio Salazar-Enciso (12228458)

“…Altogether, Ca_v1.2, SERCA pump, RyRs, and BK_Ca channels work as a functional unit at the PM-SR nanodomain, regulating intracellular Ca²⁺ and vascular function. …”

DataSheet_1_Associations of chest X-ray trajectories, smoking, and the risk of lung cancer in two population-based cohort studies.docx by Ya Liu (205636)

“…However, the associations of CXR trajectories, smoking and LC risk remain unknown.</p>Methods<p>A total of 52,486 participants from the PLCO and 22,194 participants from the NLST were included. …”

The levels of secretion of endogenous and exogenous proteins are affected by SECReTE strength. by Osnat Cohen-Zontag (6900233)

“…<p><b>(A) SECReTE enhances the ability to grow on sucrose.…”

Simulations of multiple regulators with different weights and heterogeneous <i>K</i>_{<i>n</i>,<i>i</i>} (related to Fig 4). by Xiangrui Ji (16705908)

“…(C) The deletion of inhibitors is equivalent to a decrease in the division threshold. If the threshold change is small, e.g., <i>inh3</i>Δ, <i>V</i>_<i>b</i> is still proportional to the equivalent threshold so that the CV of <i>V</i>_<i>b</i> remains constant. …”

Transition Metal Complexes with Sulfur Ligands. 130. Synthesis, Structure, and Reactivity of the Sulfur-Rich Ruthenium Hydride Complexes [Ru(H)(PR₃)(‘S₄')]<su... by Dieter Sellmann (2539633)

“…They were isolated as [Li(THF)(Et₂O)][Ru(H)(PR₃)(‘S₄')] (R = ⁱPr (<b>1a</b>), Cy (<b>1b</b>), Na[Ru(H)(PCy₃)(‘S₄')]·2BEt₃·0.5DMSO (<b>2a</b>), and the solvent-free Na[Ru(H)(PPh₃)(‘S₄')]·2BEt₃ (<b>2b</b>). …”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…CO2 concentration (ppm), relative humidity (%), and temperature (℃) during each manual measurement were logged every 5 sec for 2 min with a handheld logger (model MI70, Vaisala Inc.). NEE and ER were calculated from the linear change of the CO₂ concentration in the chamber by the ideal gas equation, and gross ecosystem productivity (GEP) was obtained by subtracting ER from NEE.…”

Lung-Sparing Surgery for Treatment of Pulmonary Metastases: VATS Right Anterior Segmentectomy (S3) and RLL Wedge Resection by Andres Obeso (4544185)

“…By contrast, centrally located lesions usually require more extensive resections which may be necessary to obtain a complete excision. In these cases, lung-sparing techniques are preferable so as to preserve healthy pulmonary tissue and decrease minimally the pulmonary function in case future pulmonary resections are needed. …”

Mixed Ligand Copper(II) Complexes of <i>N</i>,<i>N</i>-Bis(benzimidazol-2-ylmethyl)amine (BBA) with Diimine Co-Ligands: Efficient Chemical Nuclease and Protease Activities and Cyto... by Rangasamy Loganathan (2081950)

“…Interestingly, the 5,6-dmp complex <b>3</b> is selective in exhibiting a positive induced CD band (ICD) upon binding to DNA suggesting that it induces a B to A conformational change. …”

The funnel plot of visual analog scale score. by Guimei Guo (4127074)

“…The change in visual analog scale (VAS) score 3 months post intervention (MD = -0.33, 95% Cl: -0.52 to -0.13, P = 0.001), 6 months (MD = -0.69, 95% Cl: -0.90 to -0.48, P < 0.00001), 12 months (MD = -0.75, 95% Cl: -1.05 to -0.46, P < 0.00001), ≥ 24 months (MD = -1.05, 95% Cl: -1.20 to -0.89, P < 0.00001), and the last follow-up (MD = -0.75, 95% Cl: -0.97 to -0.54, P < 0.00001). The PRP also showed a decrease in VAS score compared to baseline than the non-PRP at 3 months (MD = -0.29, 95% Cl: -0.41 to -0.17, P = 0.003), 6 months (MD = -0.63, 95% Cl: -0.96 to -0.30, P = 0.0002), 12 months (MD = -0.78, 95% Cl: -1.22 to -0.33, P = 0.0006), ≥ 24 months (MD = -1.11, 95% Cl: -1.27 to -0.96, P < 0.00001), and the last follow-up (MD = -0.74, 95% Cl: -1.05 to -0.43, P < 0.00001). …”

Intervention characteristics of included studies. by Guimei Guo (4127074)

“…The change in visual analog scale (VAS) score 3 months post intervention (MD = -0.33, 95% Cl: -0.52 to -0.13, P = 0.001), 6 months (MD = -0.69, 95% Cl: -0.90 to -0.48, P < 0.00001), 12 months (MD = -0.75, 95% Cl: -1.05 to -0.46, P < 0.00001), ≥ 24 months (MD = -1.05, 95% Cl: -1.20 to -0.89, P < 0.00001), and the last follow-up (MD = -0.75, 95% Cl: -0.97 to -0.54, P < 0.00001). The PRP also showed a decrease in VAS score compared to baseline than the non-PRP at 3 months (MD = -0.29, 95% Cl: -0.41 to -0.17, P = 0.003), 6 months (MD = -0.63, 95% Cl: -0.96 to -0.30, P = 0.0002), 12 months (MD = -0.78, 95% Cl: -1.22 to -0.33, P = 0.0006), ≥ 24 months (MD = -1.11, 95% Cl: -1.27 to -0.96, P < 0.00001), and the last follow-up (MD = -0.74, 95% Cl: -1.05 to -0.43, P < 0.00001). …”

GRADE evaluation of evidence quality. by Guimei Guo (4127074)

“…The change in visual analog scale (VAS) score 3 months post intervention (MD = -0.33, 95% Cl: -0.52 to -0.13, P = 0.001), 6 months (MD = -0.69, 95% Cl: -0.90 to -0.48, P < 0.00001), 12 months (MD = -0.75, 95% Cl: -1.05 to -0.46, P < 0.00001), ≥ 24 months (MD = -1.05, 95% Cl: -1.20 to -0.89, P < 0.00001), and the last follow-up (MD = -0.75, 95% Cl: -0.97 to -0.54, P < 0.00001). The PRP also showed a decrease in VAS score compared to baseline than the non-PRP at 3 months (MD = -0.29, 95% Cl: -0.41 to -0.17, P = 0.003), 6 months (MD = -0.63, 95% Cl: -0.96 to -0.30, P = 0.0002), 12 months (MD = -0.78, 95% Cl: -1.22 to -0.33, P = 0.0006), ≥ 24 months (MD = -1.11, 95% Cl: -1.27 to -0.96, P < 0.00001), and the last follow-up (MD = -0.74, 95% Cl: -1.05 to -0.43, P < 0.00001). …”

PRISMA flow diagram. by Guimei Guo (4127074)

“…The change in visual analog scale (VAS) score 3 months post intervention (MD = -0.33, 95% Cl: -0.52 to -0.13, P = 0.001), 6 months (MD = -0.69, 95% Cl: -0.90 to -0.48, P < 0.00001), 12 months (MD = -0.75, 95% Cl: -1.05 to -0.46, P < 0.00001), ≥ 24 months (MD = -1.05, 95% Cl: -1.20 to -0.89, P < 0.00001), and the last follow-up (MD = -0.75, 95% Cl: -0.97 to -0.54, P < 0.00001). The PRP also showed a decrease in VAS score compared to baseline than the non-PRP at 3 months (MD = -0.29, 95% Cl: -0.41 to -0.17, P = 0.003), 6 months (MD = -0.63, 95% Cl: -0.96 to -0.30, P = 0.0002), 12 months (MD = -0.78, 95% Cl: -1.22 to -0.33, P = 0.0006), ≥ 24 months (MD = -1.11, 95% Cl: -1.27 to -0.96, P < 0.00001), and the last follow-up (MD = -0.74, 95% Cl: -1.05 to -0.43, P < 0.00001). …”

Summary data and analyses. by Guimei Guo (4127074)

“…The change in visual analog scale (VAS) score 3 months post intervention (MD = -0.33, 95% Cl: -0.52 to -0.13, P = 0.001), 6 months (MD = -0.69, 95% Cl: -0.90 to -0.48, P < 0.00001), 12 months (MD = -0.75, 95% Cl: -1.05 to -0.46, P < 0.00001), ≥ 24 months (MD = -1.05, 95% Cl: -1.20 to -0.89, P < 0.00001), and the last follow-up (MD = -0.75, 95% Cl: -0.97 to -0.54, P < 0.00001). The PRP also showed a decrease in VAS score compared to baseline than the non-PRP at 3 months (MD = -0.29, 95% Cl: -0.41 to -0.17, P = 0.003), 6 months (MD = -0.63, 95% Cl: -0.96 to -0.30, P = 0.0002), 12 months (MD = -0.78, 95% Cl: -1.22 to -0.33, P = 0.0006), ≥ 24 months (MD = -1.11, 95% Cl: -1.27 to -0.96, P < 0.00001), and the last follow-up (MD = -0.74, 95% Cl: -1.05 to -0.43, P < 0.00001). …”

The funnel plot of Harris hip score. by Guimei Guo (4127074)

“…The change in visual analog scale (VAS) score 3 months post intervention (MD = -0.33, 95% Cl: -0.52 to -0.13, P = 0.001), 6 months (MD = -0.69, 95% Cl: -0.90 to -0.48, P < 0.00001), 12 months (MD = -0.75, 95% Cl: -1.05 to -0.46, P < 0.00001), ≥ 24 months (MD = -1.05, 95% Cl: -1.20 to -0.89, P < 0.00001), and the last follow-up (MD = -0.75, 95% Cl: -0.97 to -0.54, P < 0.00001). The PRP also showed a decrease in VAS score compared to baseline than the non-PRP at 3 months (MD = -0.29, 95% Cl: -0.41 to -0.17, P = 0.003), 6 months (MD = -0.63, 95% Cl: -0.96 to -0.30, P = 0.0002), 12 months (MD = -0.78, 95% Cl: -1.22 to -0.33, P = 0.0006), ≥ 24 months (MD = -1.11, 95% Cl: -1.27 to -0.96, P < 0.00001), and the last follow-up (MD = -0.74, 95% Cl: -1.05 to -0.43, P < 0.00001). …”

Mixed Ligand Copper(II) Complexes of <i>N</i>,<i>N</i>-Bis(benzimidazol-2-ylmethyl)amine (BBA) with Diimine Co-Ligands: Efficient Chemical Nuclease and Protease Activities and Cyto... by Rangasamy Loganathan (2081950)

“…Interestingly, the 5,6-dmp complex <b>3</b> is selective in exhibiting a positive induced CD band (ICD) upon binding to DNA suggesting that it induces a B to A conformational change. …”

RNA expression of myeloid growth factor signaling ligands and their receptors found in PDAC CTC and M-FB after PortalBMC <i>ex vivo</i> culture. by Juan Pablo Arnoletti (12275290)

“…No significant decrease was seen in CTC <i>CSF1</i> RNA expression with any treatment, in contrast to effects seen at the <i>CSF1</i> gene product level (M-CSF/CSF1, <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0265725#pone.0265725.g005" target="_blank">Fig 5</a></b>). …”

yorku.grassland-disturbed.october4-2016.csv by Stephen DiCorpo (3127707)

“…</p> <p> </p> <p><b>Hypothesis - Grassland Survey 2:</b></p> <p>The total number of flowers recorded will decrease as canopy cover increases.</p> <p><b>Prediction - Grassland Survey 2:</b></p> <p>There should be a correlation between the amount of flowers counted and the canopy coverage found above the flowers. …”

SEAwise Report on the design of an effective ecosystem-based fisheries management by Gerjan Piet (20926951)

“…If the aim is to protect biodiversity, a reduction of the bycatch of other ecosystem components like mammals, turtles or birds or a decrease of the physical disturbance of the seafloor is required. …”

Fitness reaction norms and experimental evolution design. by Thiago S. Guzella (5920229)

“…<p>(A) Heritable genotype-by-environment (GxE) fitness variance implies that genotypes (colored lines) have different growth rates along the value of the environmental factor(s) considered [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007731#pgen.1007731.ref003" target="_blank">3</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007731#pgen.1007731.ref013" target="_blank">13</a>]. …”