Data_Sheet_1_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP by Zhi Liu (165121)

“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”

S1 File - by Liuling Luo (18570257)

“…<div><p>Echinatin is an active ingredient in licorice, a traditional Chinese medicine used in the treatment of inflammatory disorders. …”

Image_2_DNA Methyltransferases Contribute to Cold Tolerance in Ticks Dermacentor silvarum and Haemaphysalis longicornis (Acari: Ixodidae).TIF by Desmond Onyeka Agwunobi (11333943)

“…<p>DNA methylation, mediated by DNA methyltransferases (Dnmts), is a typical epigenetic process that plays an important role in affecting organism acclimatization and adaptation to environmental changes. …”

Data Sheet 1_Global burden and trends of childhood non-Hodgkin lymphoma from 1990 to 2021.pdf by Jing Xie (180526)

“…Background<p>Childhood non-Hodgkin lymphoma (NHL) is a significant contributor to pediatric cancer morbidity and mortality worldwide. …”

DataSheet_1_Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction... by Siqi Xu (429196)

“…We confirmed this mechanistic effect in a CLP-induced sepsis model of intestinal SIRT3 conditional-knockout mice, and found that melatonin preserved mitochondrial function and induced autophagy of small-intestine epithelial cells; these effects were dependent on SIRT3 activation. …”

Table_10_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx by Jipeng Yan (8473710)

“…Notably, 5 optimal ASV-based microbial markers were identified as the diagnostic model of AL amyloidosis and the AUC value of the train set and the test set was 0.8549 (95% CI 0.7310-0.9789) and 0.8025 (95% CI 0.5771-1), respectively. With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”

Potential role of an antimicrobial peptide, KLK in inhibiting lipopolysaccharide-induced macrophage inflammation by Pornpimon Jantaruk (4397911)

“…Our findings therefore proved anti-inflammatory potential of the KLK peptide and provide direct evidence for therapeutic application of KLK as a novel anti-inflammatory agent.</p></div>…”

Lower serum LH level was related to poor embryo quality and adverse pregnancy outcomes in fixed GnRH antagonist protocol with estradiol pretreatment by Ying Chen (9697)

“…</p> <p>Lower serum LH represents as a potential indicator for embryo quality and reproductive outcomes in GnRH antagonist fixed protocol pretreated with estradiol. …”

Table1_Bioinformatic analysis and experimental validation identified DNA methylation–Related biomarkers and immune-cell infiltration of atherosclerosis.XLS by Congjian Xu (587410)

“…Western blot was performed to detect the protein expression levels of monocyte markers.</p><p>Results: A total of 110, 695 DMPs, and 918 DMRs were screened in the whole genome. …”

Table_1_Metagenomics Versus Metatranscriptomics of the Murine Gut Microbiome for Assessing Microbial Metabolism During Inflammation.XLSX by Juan Jovel (403399)

“…Functions ostensibly increasing bacteria pathogenesis were also found upregulated, perhaps as a consequence of increased abundance of Proteobacteria. …”

Table_2_Physiological, Proteomic Analysis, and Calcium-Related Gene Expression Reveal Taxus wallichiana var. mairei Adaptability to Acid Rain Stress Under Various Calcium Levels.DO... by Wen-Jun Hu (447700)

“…Studies have shown that AR can leach calcium ions from plants and soil. Calcium (Ca) is also a crucial regulator of the plant stress response, whereas there are few reports on how Ca regulates the response of AR-resistant woody plants to AR stress. …”

Table_1_Effect of four fluoroquinolones on the viability of bladder cancer cells in 2D and 3D cultures.docx by Tomasz Kloskowski (622176)

“…</p>Results and Discussion<p>All tested fluoroquinolones in 2D culture decreased the viability of both tested cell lines in a dose- and timedependent manner. …”

Table_1_Effects of Systemic Physiology on Mapping Resting-State Networks Using Functional Near-Infrared Spectroscopy.DOCX by Androu Abdalmalak (7364030)

“…In the present work, we hypothesized that additional measurements with short channels, heart rate, mean arterial pressure, and end-tidal CO₂ could provide a better understanding of the effects of systemic physiology on fNIRS-based resting-state networks. …”

Low-speed Rear-end Collisions: Kinematic and Clinical Responses (Video, MRI findings, EMG/NCS results) by Hee Young Lee (22195417)

“…While 58.3% of participants reported immediate post-collision pain, this decreased to 25% within a week, primarily affecting the cervical spine and lower back.…”

Image 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.png by Yiwen Li (354034)

“…PI3K signaling pathway was identified as a central mediator of the microbiota interaction in DMIRI. …”

DataSheet1_Human bone marrow stromal cells: the impact of anticoagulants on stem cell properties.pdf by Michaela Ferencakova (16999290)

“…On the other hand, RNA-seq analysis revealed an increased expression of genes involved in nucleotide metabolism and cellular metabolism in cultivated vs. non-cultivated BMSCs regardless of the anticoagulant, while genes involved in inflammation and chromatin remodeling were decreased in cultivated vs. non-cultivated BMSCs.</p><p>Conclusion: The type of anticoagulant in BMSC isolation did not have a significant impact on molecular characteristics and cellular composition, while in vitro cultivation caused the major change in the transcriptomics of BMSCs, which is important for future protocols using BMSCs in regenerative medicine and clinics.…”

DataSheet_1_Comprehensive analysis of B3 family genes in pearl millet (Pennisetum glaucum) and the negative regulator role of PgRAV-04 in drought tolerance.docx by Yin-Hua Wang (12522223)

“…To delve deeper into the abiotic stress roles of the B3 family, we focused on a specific gene within the RAV subfamily, PgRAV-04, cloning it and overexpressing it in tobacco. …”

DataSheet_4_SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals.zip by Yi-Kong Lin (12882812)

“…</p>Results<p>Increased estrogen-estrogen receptor (ER) α signaling and decreased progesterone receptor isoform B (PRB) expression synergistically led to a hypo-autophagy state in eESCs, which further inhibited the apoptosis of eESCs. …”

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …”

Protective Role of Acidic pH-Activated Chloride Channel in Severe Acidosis-Induced Contraction from the Aorta of Spontaneously Hypertensive Rats by Zhiyong Ma (95708)

“…In the present study, we investigate whether this channel participates in reactions of the thoracic aorta to severe acidosis and whether it plays a role in hypertension. We measured isometric contraction in thoracic aorta rings from spontaneously hypertensive rats (SHRs) and normotensive Wistar rats. …”