Top 16 pfam domains with least selective active drugs. by Tyler William H. Backman (3726991)

“…For example, the non-FDA approved compounds active against targets with the PF00183 domain are active against a median of 12 targets with distinct GenBank identifiers, so this domain has a 12 after the slash in the first column.…”

Serial Low Doses of Sorafenib Enhance Therapeutic Efficacy of Adoptive T Cell Therapy in a Murine Model by Improving Tumor Microenvironment by Hui-Yen Chuang (451323)

“…Not only immunosuppressive factors but myeloid derived suppressive cells (MDSCs) and regulatory T cells (Tregs) were decreased in sorafenib-treated group, indicating that augmentation of tumor inhibition and function of CD8+ T cells by serial low doses of sorafenib were <i>via</i> reversing the immunosuppressive microenvironment. …”

Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: influence of gender, smoking, and BMI by Carly E. Herbison (6198674)

“…Males were more likely to be RR than NR (adjusted, <i>p</i> = 0.05). In addition, we present a novel AUC measure (AUC_R), for use when the TSST baseline concentration is higher than later time points. …”

Effects of polyphenol-rich traditional herbal teas on obesity and oxidative stress in rats fed a high-fat–sugar diet by Iftikhar, Neelam

“…A significant decrease in the levels of serum TC, TG, LDL, and VLDL was observed in all the treatment groups in comparison with the HFSDC group. …”
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Supplementary Material for: Depression Scores following Ventral Intermediate Nucleus Deep Brain Stimulation for Essential Tremor: A Meta-Analysis by Gupta R. (10667589)

“…There was also a statistically significant decrease in depression postoperatively (9 cohorts, <i>n</i> = 352, SMD = −0.31, 95% CI [−0.46 to −0.16], <i>p</i> < 0.0001). …”

Presentation1_Implementation of a heart failure educational intervention for patients with recent admissions for acute decompensated heart failure.pptx by Sarah Stahlman (15415499)

“…These results were driven by a decrease in admissions and ED visits for HF symptoms. …”

Data_Sheet_1_Case Report: Zolpidem’s paradoxical restorative action: A case report of functional brain imaging.pdf by Jennifer Boisgontier (11138931)

“…Whole brain rest cerebral blood flow (CBF) and resting state functional connectivity using Pearson coefficient correlations between pairs of regions of interest were investigated two-by-two at the different time points. A comparison between postoperative and preoperative images showed a significant decrease in rest CBF in the left supplementary motor area, Broca’s area, and the left striatum and a decrease in functional connectivity within the dentato-thalamo-cortical and cortico-striato-pallido-thalamo-cortical loops. …”

Renal and vascular effects of kallikrein inhibition in a model of <i>Lonomia obliqua</i> venom-induced acute kidney injury by Markus Berger (216106)

“…In addition, kallikrein inhibition also ameliorated venom-induced blood incoagulability and decreased kidney tissue factor expression</p><p>Conclusions/Significance</p><p>These data indicated that kallikrein and consequently kinin release have a key role in kidney injury and vascular remodeling. …”

Intensification of Antiretroviral Therapy with a CCR5 Antagonist in Patients with Chronic HIV-1 Infection: Effect on T Cells Latently Infected by Carolina Gutiérrez (192894)

“…</p> <h3>Conclusions</h3><p>Intensification with MVC was associated with a trend to a decrease in the size of the latent HIV-1 reservoir in memory T cells. …”

Presentation2_Implementation of a heart failure educational intervention for patients with recent admissions for acute decompensated heart failure.pptx by Sarah Stahlman (15415499)

“…These results were driven by a decrease in admissions and ED visits for HF symptoms. …”

Relative losses and gains for a combination of planning and evaluation scenarios, indicated by negative (loss) and positive (gain) values in the y axis. by Heini Kujala (279665)

“…Negative values in the x axis indicate species expected to experience a decrease in future climatic suitability.</p>…”

Supplementary Figure S6 from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors by Yong Li (15029)

Average DCE enhancement curves of control (A) and MCT (B) mice in each group pre- and post-chemo time points. by Mehran Baboli (8957807)

“…<p>There is a decrease in enhancement with the control group, while the MCT mice remained fairly level after the scheduled chemotherapy regimen.…”

Survival curves after a heat-shock with heterogeneity in aging rates (HRM) and heterogeneity in aging timing (HTM), on the right column. by Yann Le Cunff (102173)

“…Both the experimental data and the simulated curves exhibit a two stage decrease: a first quick, strong fall followed by a slowing down. (, 500 individuals per simulation, 500 simulations per curve).…”

Gene expression of collagen 3α1 in laser capture microdissected airways (bronchioles) (6A) and parenchyma (6B). by Steven Zhou (440982)

Position weight matrix of nucleotides in the DPBF1&2 element that correlate with a shift in the DEM when combined with the evening element. by Pavlos Stephanos Bekiaris (4732863)

“…<p>The size of the letters at each position indicate which bases lead to a decrease in the performance of the CRE pair when mutated prior to the EDCC analysis. …”

Table_1_Relationships between subjective experience, electroencephalogram, and heart rate variability during a series of cosmetic behavior.docx by Hiroki Moriya (305670)

“…Each theta-band (4–6 Hz) power, alpha-band (8–13 Hz) power of the EEG, and heart rate variability measures were subjected to a principal component analysis separately. The linear mixed models indicated that the variation in the self-confidence score and the negative emotion score was explained only by the steps of cosmetic behaviors, that is, self-confidence increased while negative emotions decreased as the steps of cosmetic behaviors proceeded. …”

Data Sheet 1_First-in-human study of CPL’116 – a dual JAK/ROCK inhibitor – in healthy subjects.docx by Piotr J. Rudzki (20970821)

“…A decrease in MLC phosphorylation indicated a potential trend at p < 0.1.…”

Highly Efficient Thermally Activated Delayed Fluorescence in Dinuclear Ag(I) Complexes with a Bis-Bidentate Tetraphosphane Bridging Ligand by Jin Chen (130241)

“…The remarkable decrease of the decay time indicates that thermal population of a short-lived singlet state (S₁ state) increases as the temperature increases. …”

Highly Efficient Thermally Activated Delayed Fluorescence in Dinuclear Ag(I) Complexes with a Bis-Bidentate Tetraphosphane Bridging Ligand by Jin Chen (130241)

“…The remarkable decrease of the decay time indicates that thermal population of a short-lived singlet state (S₁ state) increases as the temperature increases. …”