Progressive Cognitive Deficit, Motor Impairment and Striatal Pathology in a Transgenic Huntington Disease Monkey Model from Infancy to Adulthood by Anthony W. S. Chan (253096)

“…Along with progressive cognitive and motor impairment, neuroimaging revealed a progressive reduction in striatal volume. Magnetic resonance spectroscopy at 48 months of age revealed a decrease of N-acetylaspartate (NAA), further suggesting neuronal damage/loss in the striatum. …”

Data_Sheet_1_Inferring the Significance of the Polyamine Metabolism in the Phytopathogenic Bacteria Pseudomonas syringae: A Meta-Analysis Approach.PDF by Leandro Solmi (12509083)

“…Furthermore, data suggest that a proper bacterial response to oxidative conditions requires a decrease in polyamine production. …”

Curcumin affects gene expression and reactive oxygen species via a PKA dependent mechanism in <i>Dictyostelium discoideum</i> by William S. Swatson (4591873)

“…This is followed by later unique transcriptional changes and a protein kinase A dependent decrease in catalase A and three superoxide dismutase enzymes. …”

Data_Sheet_1_Identification of a New de Novo Mutation Underlying Regressive Episodic Ataxia Type I.DOCX by Zeynep S. Karalok (5556416)

“…<p>Episodic ataxia type 1 (EA1), a Shaker-like K⁺channelopathy, is a consequence of genetic anomalies in the KCNA1 gene that lead to dysfunctions in the voltage-gated K⁺ channel Kv1. 1. …”

Reproductive behaviour of a North African endemic damselfly, <i>Platycnemis subdilatata</i> (Odonata: Platycnemididae) and probable senescence effects by Rassim Khelifa (2867750)

“…Clutch size and egg deposition rate pattern through age showed an increase in early mature life followed by a decrease later on.</p>…”

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic by Aaron Mobley (412870)

“…</p><p>Methods and Findings</p><p>To examine a microcosm of the academic experience with data reproducibility, we surveyed the faculty and trainees at MD Anderson Cancer Center using an anonymous computerized questionnaire; we sought to ascertain the frequency and potential causes of non-reproducible data. …”

Online supplementary data from Projecting a second wave of COVID-19 in Japan with variable interventions in high-risk settings by Sung-mok Jung (10457737)

“…Projections showed that a 50% decrease in the high-risk transmission is required to keep <i>R</i> < 1 in both locations—a level necessary to maintain control of the epidemic and minimize the risk of resurgence.…”

Table_3_The Expansion of a Single Bacteriophage Leads to Bacterial Disturbance in Gut and Reduction of Larval Growth in Musca domestica.docx by Xinyu Zhang (14029)

Representation of Sound Objects within Early-Stage Auditory Areas: A Repetition Effect Study Using 7T fMRI by Sandra Da Costa (734188)

“…Their semantic representations were shown to yield repetition suppression effects, i. e. a decrease in activity during exposure to a sound that is perceived as belonging to the same source as a preceding sound. …”

Image_3_Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy.pdf by Yasuo Kitajima (3493466)

“…Using this model, we found that proteasome dysfunction in adult muscles resulted in muscle wasting and a decrease in the myofiber size. Immunoblotting analysis showed that the amounts of ubiquitinated proteins were markedly higher in muscles of Rpt3-deficient mice than in those of the control mice. …”

Image_1_The Expansion of a Single Bacteriophage Leads to Bacterial Disturbance in Gut and Reduction of Larval Growth in Musca domestica.tiff by Xinyu Zhang (14029)

Table_4_The Expansion of a Single Bacteriophage Leads to Bacterial Disturbance in Gut and Reduction of Larval Growth in Musca domestica.docx by Xinyu Zhang (14029)

DataSheet_1_Evolution of Advanced Chronic Lymphoid Leukemia Unveiled by Single-Cell Transcriptomics: A Case Report.pdf by Pavel Ostasov (9584723)

“…Here, we apply single-cell RNA-seq to a CLL case, sampled at diagnosis and relapse, that was treated with FCR (Fludarabine, Cyclophosphamide, Rituximab) and underwent a dramatic decrease in CD19 expression during disease progression. …”

Table_2_The Expansion of a Single Bacteriophage Leads to Bacterial Disturbance in Gut and Reduction of Larval Growth in Musca domestica.docx by Xinyu Zhang (14029)

Clinical utility of reproductive carrier screening for preconception and pregnant couples for multiple genetic conditions: a systematic review and meta-analysis by Tianjiao Wang (761650)

“…Pooled estimations were as follows: the prenatal diagnosis (PND) rate among pregnant HRCs 0.644 (95% CI = 0.364, 0.923), the termination rate among affected pregnancies 0.714 (95% CI = 0.524, 0.904), and the rate of in-vitro fertilization (IVF) with preimplantation genetic testing (PGT) 0.631 (95% CI = 0.538, 0.725). There is a statistically significant decrease in the rates of undertaking PND and termination as the number of screened conditions increases. …”

Post-stimulus undershoot and vasomotion persist with different GC activation levels. by William Davis Haselden (9175156)

“…<p>All simulations in this figure used a dynamic model. An arteriole sensitivity of m = 4 was used. …”

The effectiveness of targeted relative to empiric prophylaxis on infectious complications after transrectal ultrasound-guided prostate biopsy: a meta-analysis by Scott, S.

“…Overtreatment associated with augmented prophylaxis approaches may be reduced as a result. Further prospective assessment and cost?…”
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An enhanced distance-dependent electric field model for contact-separation triboelectric nanogenerator: Air-breakdown limit as a case study by Ahmed, Anas A.

“…The maximum surface charge density that can be obtained without air breakdown was predicted to be lateral sizedependent. It shows a monotonical decrease from 51.94 to 33.59 µC/m2 with a lateral size increase from 0.5 to 10 cm. …”
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Data_Sheet_1_Neurotransmitter content heterogeneity within an interneuron class shapes inhibitory transmission at a central synapse.PDF by Dimitri Dumontier (14326518)

“…We isolate a slow spillover component of GrCs inhibition that is also affected by the expression of GlyT2, leading to a 56% decrease in relative charge. …”

Data_Sheet_1_Treatment Experience of 210 Pediatric Patients With Extraordinary Daytime Urinary Frequency: A Prospective Study.DOCX by Yan Li (23143)

“…The patients randomized received non-drug treatment (counseling), drug treatment (lactulose), or combination therapy. A therapeutic effect was defined by a decrease of>10% of the urination frequency.…”