A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair by Tim Leschinger (6425840)

“…<p>A non-anatomical reinsertion of the supraspinatus medially to the original footprint to avoid over-tensioning of the tendon in large and retracted tears is one surgical option in rotator cuff (RC) repair. …”

A Genetically Hard-Wired Metabolic Transcriptome in <em>Plasmodium falciparum</em> Fails to Mount Protective Responses to Lethal Antifolates by Karthikeyan Ganesan (269200)

“…It was of interest to learn how DNA microarrays may be used to study drug action in malaria parasites. In one large, tightly controlled study involving 123 microarray hybridizations between cDNA from isogenic drug-sensitive and drug-resistant parasites, a lethal antifolate (WR99210) failed to over-produce RNA for the genetically proven principal target, dihydrofolate reductase-thymidylate synthase (DHFR-TS). …”

DataSheet2_Effects of Pharmacist-Led Clinical Pathway/Order Sets on Cancer Patients: A Systematic Review.docx by Zhiyuan Tan (3930584)

“…They were not used in pharmacotherapy until recently. After screening a large number of publications, we found that PLCOs were rarely accessible.…”

(a) A HCT 116 control spheroid stained for proliferating cells using Ki-67 (green) and for hypoxia using EF5 (red) (b) a HCT 116 spheroid treated with 50 nM of gemcitabine showing... by David Robert Grimes (603169)

“…This suggests a marked decrease in OCR for treated spheroids.…”

Data_Sheet_1_Evaluation of cellular activity in response to sleep deprivation by a comprehensive analysis of the whole mouse brain.docx by Takuya Urushihata (11431170)

“…From the analysis of 14 brain regions, cellular activity was significantly increased in the olfactory areas and decreased in the medulla by the two SD methods. From the analysis of the further subdivided 348 regions, cellular activity was significantly increased in the vascular organ of the lamina terminalis, lateral hypothalamic area, parabigeminal nucleus, ventral tegmental area, and magnocellular reticular nucleus, and decreased in the anterior part of the basolateral amygdalar nucleus, nucleus accumbens, septohippocampal nucleus, reticular nucleus of the thalamus, preoptic part of the periventricular hypothalamic nucleus, ventromedial preoptic nucleus, rostral linear nucleus raphe, facial motor nucleus, vestibular nuclei, and some fiber tracts (oculomotor nerve, genu of corpus callosum, and rubrospinal tract) by the two SD methods. …”

Image 1_Systematic evaluation of plant metals/metalloids accumulation efficiency: a global synthesis of bioaccumulation and translocation factors.jpeg by Wenbin Huang (452904)

“…<p>Phytoremediation, which involves the use of plants to accumulate and translocate metals and metalloids, represents a promising strategy for environmental remediation. …”

Supplementary Material for: Relative Blood Volume Monitoring during Continuous Renal Replacement Therapy (CRRT): A Prospective Observational Study by Maeda A. (6310913)

“…Finally, RBV decreased significantly more when patients received a high NUF rate (>1.75 ml/kg/h) compared to low or moderate NUF rates (5.32% vs 1.93% or 1.97%, p<0.001). …”

Experimental studies addressing the longevity of <i>Bacillus subtilis</i> spores – The first data from a 500-year experiment by Nikea Ulrich (5154149)

“…A set of vials containing a defined concentration of desiccated <i>B</i>. …”

Supplementary Material for: A Comparison of the Anticoagulation Efficacy and Safety of Epoprostenol to Heparin and Citrate in Children Receiving Continuous Renal Replacement Therap... by Sondhi E. (19087247)

“…Therefore, the primary aim of this study was to assess the efficacy and safety of epoprostenol as compared to heparin and citrate anticoagulation in a pediatric cohort. Methods: We performed a retrospective analysis of all patients <18 years of age admitted to an academic quaternary care children’s hospital from 2017-2022 who received epoprostenol, heparin, or citrate exclusively for CRRT anticoagulation. …”

Video2_A 3D cell culture system for bioengineering human neuromuscular junctions to model ALS.MP4 by Bita Massih (7486964)

“…Finally, we applied this system as an in vitro model to study the pathophysiology of Amyotrophic Lateral Sclerosis (ALS) and found a decrease in neuromuscular coupling and muscle contraction in co-cultures with MNs harboring ALS-linked SOD1 mutation. …”

Image 6_Systematic evaluation of plant metals/metalloids accumulation efficiency: a global synthesis of bioaccumulation and translocation factors.tif by Wenbin Huang (452904)

“…<p>Phytoremediation, which involves the use of plants to accumulate and translocate metals and metalloids, represents a promising strategy for environmental remediation. …”

Inhaled Long-Acting β2-Agonists Do Not Increase Fatal Cardiovascular Adverse Events in COPD: A Meta-Analysis by Ning Xia (196015)

“…<div><p>Background</p><p>The cardiovascular safety of inhaled long-acting β₂-agonists (LABAs) in patients with chronic obstructive pulmonary disease (COPD) is a controversial problem. Certain studies have suggested that inhaled LABAs lead to an increased risk of cardiovascular events in patients with COPD. …”

Table_1_Partnership and relationship happiness in endometriosis related chronic pelvic pain: a multicenter case–control study.docx by Samia el Hadad (19844874)

“…</p>Conclusion<p>Given the significance of partnership in dealing with chronic diseases and the connection between symptoms of endometriosis and a decrease in partnership quality, it is essential to incorporate strategies that alleviate the negative impacts on relationships for both partners into medical support.…”

Image_1_The Effect of Magnesium Intake on Stroke Incidence: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.TIF by Binghao Zhao (7143560)

“…Importantly, high-risk females who had a body mass index (BMI) ≥25 kg/m² and who were subjected to a ≥12 y follow-up exhibited a greater decrease in RRs as a result of magnesium intake. …”

Table_1_FgVps9, a Rab5 GEF, Is Critical for DON Biosynthesis and Pathogenicity in Fusarium graminearum.doc by Chengdong Yang (3132015)

“…In this study, we have identified and characterized a Rab5 guanine nucleotide exchange factor (GEF), the Vps9 homolog FgVps9, in F. graminearum. …”

Image_5_The Effect of Magnesium Intake on Stroke Incidence: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.TIF by Binghao Zhao (7143560)

“…Importantly, high-risk females who had a body mass index (BMI) ≥25 kg/m² and who were subjected to a ≥12 y follow-up exhibited a greater decrease in RRs as a result of magnesium intake. …”

DataSheet1_Prenylated phenolics from Morus alba against MRSA infections as a strategy for wound healing.docx by Gabriela Škovranová (14193836)

“…The combination of active phenolics with kanamycin, oxacillin, and ciprofloxacin resulted in a decrease in the MIC of the antimicrobial agent. …”

Supplementary Material for: Patterns of Mitochondrial DNA Damage in Blood and Brain Tissues of a Transgenic Mouse Model of Machado-Joseph Disease by Kazachkova N. (4133302)

“…<b><i>Results:</i></b> A clear pattern of decrease in mtDNA copy number with age and accumulation of 3,867-bp deletions at the initial stages (both being more pronounced in transgenic mice) was observed. …”

DataSheet_1_Membrane lipid sensitivity to ocean warming and acidification poses a severe threat to Arctic pteropods.pdf by Silke Lischka (6683249)

“…The temperature and pCO₂ treatments chosen resembled Representative Concentration Pathway model scenarios for this century. We found a massive decrease in total lipids at elevated temperatures and at the highest CO₂ concentration (1,100 μatm) of the in situ temperature. …”

Image_1_The Effect of Chronic Exercise on Energy and Fatigue States: A Systematic Review and Meta-Analysis of Randomized Trials.JPEG by Carly L. A. Wender (12789020)

“…Our analysis revealed exercise to decrease the feelings of fatigue by a small effect size (g = −0.374; 95% CI [−0.521, −0.227]), increase energy by a small-to-moderate effect size (g = 0.415; 95% CI [0.252, 0.578]), and to increase the feeling of vitality by a moderate effect size (g = 0.537; 95% CI [0.404, 0.671]). …”