Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function by Merlijn J. Meens (4264513)

“…To determine if Cx47 plays a role in lymphatic vessel function we analysed <i>Cx47</i>^<i>-/-</i> mice. …”

Rosemary supplementation (<i>Rosmarinus oficinallis</i> L.) attenuates cardiac remodeling after myocardial infarction in rats by Bruna Paola Murino Rafacho (314860)

“…Dietary intervention on adverse cardiac remodeling after MI has significant clinical relevance. Rosemary leaves are a natural product with antioxidant/anti-inflammatory properties, but its effect on morphology and ventricular function after MI is unknown.…”

Endocytotic assay of Nec monomer and Nec-complex in garland cells. by Sandra Fausia Soukup (262702)

“…<p>(A) Formation of Nec-PPE complex. Coomassie blue stained PAGE gel showing PPE digest of Nec^ΔN. …”

datasheet1_Suppression of Esophageal Cancer Stem-like Cells by SNX-2112 Is Enhanced by STAT3 Silencing.zip by Dan-dan Xu (3766957)

“…Hence, these results provide a rationale for the therapeutic potential of the combination of SNX-2112 with shSTAT3 in esophageal cancer, and may indicate new targets for clinical intervention in human cancer.…”

Primer sequence. by Wanyan Li (9741989)

“…Overall, PAMK could alleviate LPS induced intestinal injury by enhancing intestinal barrier function, optimizing gut microbiota composition, and regulating metabolic signaling pathways. Our findings provide a novel strategy for maintaining the intestinal health of poultry and preventing intestinal diseases.…”

DataSheet6_Salvia chinensia Benth induces autophagy in esophageal cancer cells via AMPK/ULK1 signaling pathway.ZIP by Lei Jia (303610)

“…<p>Salvia chinensia Benth (Shijianchuan in Chinese, SJC) has been used as a traditional anti-cancer herb. SJC showed good anti-esophageal cancer efficacy based on our clinical application. …”

Data_Sheet_1_Milk Product Safety and Household Food Hygiene Influence Bacterial Contamination of Infant Food in Peri-Urban Kenya.docx by Vivian Hoffmann (3493676)

“…Background<p>Milk is a common infant food in peri-urban Kenya that can transmit diarrhea-causing enteric pathogens. …”

Image5_Comprehensive analysis of m7G modification patterns based on potential m7G regulators and tumor microenvironment infiltration characterization in lung adenocarcinoma.TIF by Shouzheng Ma (12264398)

“…Nonetheless, the potential regulatory role of N7-methylguanosine (m⁷G) modification in shaping and impacting the TME remains unclear.</p><p>Methods: A comprehensive analysis was performed to explore the m⁷G modification patterns based on 24 potential m⁷G regulators in 817 lung adenocarcinoma (LUAD) patients, and the TME landscape in distinct m⁷G modification patterns were evaluated. …”

Data_Sheet_1_Comparison of Calcium Balancing Strategies During Hypothermic Acclimation of Tilapia (Oreochromis mossambicus) and Goldfish (Carassius auratus).pdf by Tsung-Yu Han (5710796)

“…This difference can be attributed to alterations in the transportation parameters for Ca²⁺ influx, i.e., maximum velocity (V_max) and binding affinity (1/K_m). There was also a significant difference in the regulation of Ca²⁺ efflux between the two fishes. …”

DataSheet_1_ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylati... by Guang-Ming Yang (2203987)

“…The phosphorylated regulatory light chains (p-RLC) play a decisive role in SM contraction, and dephosphorylation of p-RLC is an effective way to relax SM. …”

Table_1_Impact of inhibition of the renin-angiotensin system on early cardiac and renal abnormalities in Sprague Dawley rats fed short-term high fructose plus high salt diet.DOCX by Sharif Hasan Siddiqui (12012206)

“…Introduction<p>The combination of a high fructose and high salt diet typical of western diet induces high blood pressure, aortic stiffening, left ventricular (LV) diastolic dysfunction and impaired renal function in rodents. …”

Data_Sheet_1_Associations of Serum Uromodulin and Its Genetic Variants With Blood Pressure and Hypertension in Chinese Adults.docx by Yang Wang (5921)

“…We aimed to examine the associations of serum uromodulin levels and its genetic variants with longitudinal blood pressure (BP) changes and hypertension incidence/risk.</p><p>Methods: A total of 514 participants from the original Baoji Salt-Sensitive Study cohort were genotyped to examine the associations of genetic variations in uromodulin gene with the longitudinal BP changes and the incidence of hypertension over 8 years of follow-up. …”

Molecular Characterization of Three PRORP Proteins in the Moss <i>Physcomitrella patens</i>: Nuclear PRORP Protein Is Not Essential for Moss Viability by Chieko Sugita (637607)

“…<div><p>RNase P is a ubiquitous endonuclease that removes the 5′ leader sequence from pre-tRNAs in all organisms. …”

Image_3_Reversal of Endothelial Extracellular Vesicle-Induced Smooth Muscle Phenotype Transition by Hypercholesterolemia Stimulation: Role of NLRP3 Inflammasome Activation.tiff by Xinxu Yuan (7446968)

“…Moreover, acid ceramidase (AC) deficiency or lysosome inhibition further exaggerated the 7-Ket-induced release of IL-1β-containing EVs in ECs. Using a Western diet (WD)-induced hypercholesterolemia mouse model, we found that endothelial-specific AC gene knockout mice (Asah1^fl/fl/EC^Cre) exhibited augmented WD-induced EV secretion with IL-1β and more significantly decreased the interaction of MVBs with lysosomes in the carotid arterial wall compared to their wild-type littermates (WT/WT). …”

The Difference in Prognostic Factors between Early Recurrence and Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Nodal Stage Differently Impacts Early and Late Recurr... by Sung Gwe Ahn (414680)

“…</p><p>Conclusions</p><p>Nodal burden had an attenuated influence on late recurrence, which suggests that, unlike early recurrence, tumor biology might have a more important role than tumor load for late recurrence in ER-positive disease.…”

Data_Sheet_1_Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis.docx by Bartosz Pilecki (3091188)

“…Here, we investigated the role of SP-D in a murine model of CS-induced inflammation. Pulmonary SP-D localization and abundance was compared between smoker and non-smoker individuals. …”

DataSheet_1_Glycine betaine increases salt tolerance in maize (Zea mays L.) by regulating Na+ homeostasis.pdf by Mingyuan Zhu (1626598)

“…GB additionally increased Na⁺ efflux in leaf protoplasts under SS condition, and treatment with sodium orthovanadate, a plasma membrane (PM) H⁺-ATPase inhibitor, significantly alleviated the positive effects of GB on Na⁺ efflux under salt stress. …”

Brown Carbon Emissions from Biomass Burning under Simulated Wildfire and Prescribed-Fire Conditions by Chase K. Glenn (19461503)

Image_7.TIF by Wei-Di He (4920472)

“…To investigate the early cold stress response of Dajiao, here we applied comparative membrane proteomics analysis for both cold-sensitive Cavendish and cold-tolerant Dajiao bananas subjected to cold stress at 10°C for 0, 3, and 6 h. A total of 2,333 and 1,834 proteins were identified in Cavendish and Dajiao, respectively. …”

General health and metabolic function are improved in ALC-treated null mice compared to saline-treated nulls. by Laura R. Schaevitz (295749)

“…<p>(<b>A</b>) Weight (g) was measured daily between postnatal day (PN) 1 and PN 45 in all mice. …”