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47461
Table_1_Preferential Effects of Cariprazine on Counteracting the Disruption of Social Interaction and Decrease in Extracellular Dopamine Levels Induced by the Dopamine D3 Receptor...
Published 2022“…As measured by microdialysis, the highest dose of cariprazine prevented a PD-induced decrease in DA levels (40–80 min post PD dose) in the medial prefrontal cortex (mPFC), whereas aripiprazole did not have a significant effect. …”
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47462
Identification of <em>IGF1</em>, <em>SLC4A4</em>, <em>WWOX</em>, and <em>SFMBT1</em> as Hypertension Susceptibility Genes in Han Chinese with a Genome-Wide Gene-Based Association S...
Published 2012“…<em>SLC4A4</em>, which encodes the electrogenic sodium bicarbonate cotransporter 1, is associated with decreased body weight/size and abnormal ion homeostasis in mice. …”
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47463
Reductive C–C Coupling from Molecular Au(I) Hydrocarbyl Complexes: A Mechanistic Study
Published 2021“…The rate of ethane formation from [Au<sub>2</sub>(μ-CH<sub>3</sub>)(PMe<sub>2</sub>Ar′)<sub>2</sub>][NTf<sub>2</sub>] increases as the steric bulk of the phosphine substituent Ar′ decreases. Monitoring the rate of ethane elimination reactions by multinuclear NMR spectroscopy provides evidence for a second-order dependence on the gem-digold methyl complexes. …”
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47464
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
Published 2021“…<i>atg5</i><sup>−/−</sup> platelets also exhibited a lower aggregation in response to agonists, and platelet-specific <i>atg5</i><sup>−/−</sup> mice exhibited delayed thrombus formation in mesenteric microvessles and decreased mortality rate due to pulmonary thrombosis. …”
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47465
dAβ expression alters memory only when associated with APPL partial loss-of-function.
Published 2015“…<i>Appl</i><sup><i>d</i></sup>/+;<i>MBSw</i>/<i>dAβ</i> flies display a score significantly decreased compared to the controls (Newman-Keuls <i>post-hoc</i>, <i>Appl</i><sup><i>d</i></sup>/+;<i>MBSw</i>/<i>dAβ</i> vs <i>Appl</i><sup><i>d</i></sup><i>/+;MBSw/+ **p</i> < 0.01, <i>Appl</i><sup><i>d</i></sup>/+; <i>MBSw</i>/<i>dAβ</i> vs <i>+</i>/<i>dAβ ***p</i> < 0.001). …”
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47466
A proposed framework for the hypothesized pathogenesis of lung abnormality among individuals with HIV and pneumonia co-infection.
Published 2019“…HIV alters the immune environment and affects the host response [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0226347#pone.0226347.ref067" target="_blank">67</a>], therefore it is hypothesized that HIV-infected individuals who contract pneumonia will have a decreased ability to clear the invading pathogen, leading to increased fibroblast activation, extracellular matrix deposition and tissue remodeling resulting in impaired gas exchange and greater lung abnormality (top right panel).…”
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47467
SPR4-peptide induces a dramatic increase in fat mass/weight in HYP and WT mice.
Published 2014“…<p>Dual Energy X-ray Absorptiometry (DEXA) measurements using a Lunar PIXImus system were carried out as described previously and discussed in methods <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0097326#pone.0097326-David2" target="_blank">[140]</a>. …”
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47468
(A) Evidence and types of selection: (Top) Schematic of the lowest mean value fractional rank value (λ) distributions for local heterozygosity in a sample of 45 European Americans...
Published 2008“…<p>(Bottom) Four kinds of putative selection sites where one of the two populations has either lower values of heterozygosity as well as a rise in S<sup>2</sup>F<sub>ST</sub> values at the same location, or a decreased local heterozygosity in both populations (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001712#pone-0001712-t001" target="_blank">Table 1</a>). …”
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47469
A Proposal for Implementation of Multi-Factor Authentication (MFA) System for Enhanced Security By Stephen Mikah Makoshi
Published 2025“…<p dir="ltr"><b>A </b><b>Proposal for Implementation of Multi-Factor Authentication (MFA) System for Enhanced Security</b><br>By Stephen Mikah Makoshi<br>April, 2025</p><p dir="ltr"><b>Introduction</b><br>As cybersecurity threats like phishing, credential theft, and data breaches continue to rise, safeguarding sensitive information has become a top priority for organizations. …”
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47470
Spectral-domain optical coherence tomography (SD-OCT) images taken from a 72-year-old female patient with neovascular age-related macular degeneration (nAMD) who received ranibizum...
Published 2025“…OCT image taken at baseline (A) reveals macular neovascularization (MNV), subretinal hyperreflective material (SHRM) and subretinal fluid (SRF). …”
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47471
Video-Assisted Thoracoscopic Lobectomy for Giant Congenital Bulla of the Left Upper Lobe: A Case Report
Published 2019“…<p>A 17-year-old woman was admitted to the authors’ hospital with left chest pain, cough, and dyspnea. …”
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47472
Supplementary Material for: Inadequate ovarian function suppression with GnRH agonists and subsequent bilateral salpingo-oophorectomy revealing ovarian stromal hyperplasia in a pre...
Published 2025“…Background: A current standard treatment for pre or perimenopausal women with high risk early-stage, hormone receptor-positive breast cancer who have undergone definitive surgery is adjuvant treatment with ovarian function suppression (OFS) with a GnRH agonist (leuprolide or goserelin) with endocrine therapy with an aromatase inhibitor (AI) or tamoxifen. …”
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47473
Model showing cellulose microfibrils with bound XyG chains presented only for diagrammatic purposes.
Published 2021“…<i>glycines</i>-susceptible outcome as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0244305#pone.0244305.g002" target="_blank">Fig 2B</a> as compared to the OE control in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0244305#pone.0244305.g002" target="_blank">Fig 2A</a>. *** XTH43-OE showing an decrease in XyG chain length and more of those chains. …”
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47474
Model comparison results.
Published 2024“…Specifically, we detect a detrimental effect (i.e., a significant decrease in the intercept) of the disgust-eliciting image in Incongruent condition (vs. …”
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47475
Coefficient estimates (log-odds scale).
Published 2024“…Specifically, we detect a detrimental effect (i.e., a significant decrease in the intercept) of the disgust-eliciting image in Incongruent condition (vs. …”
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47476
Model comparison results.
Published 2024“…Specifically, we detect a detrimental effect (i.e., a significant decrease in the intercept) of the disgust-eliciting image in Incongruent condition (vs. …”
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47477
A study of the effects of canopy coverage on the abundance of herbaceous plant species in Danby Woodlot at York University
Published 2016“…Only plants larger than 1.5m in height were counted. Having a height requirement decreased the probability of counting a non-woody plant. …”
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47478
Effects of covid-19 lockdown on physical activity, sedentary behavior, and satisfaction with life in Qatar: A preliminary study
Published 2021“…Life satisfaction decreased, with the score for “I am satisfied with my life” (ηp2 = 0.76, p < 0.001) decreasing from 28.1 ± 4.81 to 14.2 ± 6.41 arbitrary units (AU). …”
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47479
Data_Sheet_1_β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway.d...
Published 2022“…<p>Pulmonary fibrosis is a scarring disease of lung tissue, which seriously threatens human health. …”
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47480
Effects of plant-based diets in endurance athletes: a scoping review and practical nutritional recommendations – Protocol
Published 2023“…OBJECTIVES</b></p><p dir="ltr">The purpose of this scoping review is to examine the emerging scientific evidence on the plant-based diet in endurance athletes and to synthesize a series of practical dietetic-nutritional recommendations based on the body of evidence.…”