Hydroxymethylnitrofurazone (NFOH) decreases parasitaemia, parasitism and tissue lesion caused by infection with the Bolivia Trypanosoma cruzi type I strain in Swiss and C57BL/6 mic... by Cauê Benito Scarim (5222987)

“…Therefore, the results shown here pointing to the NFOH as promising compound for further preclinical studies, being a high potential drug to effective and safe chemotherapy to Chagas disease.…”

Vδ2 γδ T cell counts were increased with decreased IFNγ production in peripheral blood of sickle cell disease (SCD) patients compared to controls. by Slimane Allali (341342)

P2Y12 deficiency decreases lung metastasis but has no effect on primary tumor growth in the LLC (Lewis lung carcinoma) spontaneous pulmonary metastasis model. by Yanhua Wang (127897)

Antibody and antigen responses to nMAb vs placebo day 1–90 for Amubarvimab/ Romlusevimab. by Elizabeth S. Munroe (21568166)

Antibody and antigen responses to nMAb vs placebo day 1–90 for Tixagevimab/ Cilgavimab. by Elizabeth S. Munroe (21568166)

Antibody and antigen responses to nMAb vs placebo day 1–90 for Bamlanivimab. by Elizabeth S. Munroe (21568166)

Heatmap analysis of the expression levels of ABA, ROS and SOS-related genes. by Yangyang Wei (436909)

OP9/L cells show increased proinflammatory factor and decreased hematopoietic factor gene expression and enhance KOBA cell proliferation at the cost of supporting normal hematopoie... by Emmanuelle Supper (206081)

Increased mRNA levels of pro-inflammatory genes and decreased levels of anti-inflammatory genes in <i>Sirt2^−/−</i> mouse-derived BMDMs. by Giuseppe Lo Sasso (260287)

TLR2 deficiency decreased TGF-β1 expression, phosphorylated Smad2/3 and myofibroblasts activation induced by <i>C</i>. <i>sinensis</i>. by Yuru Wang (846969)

<i>TLR2</i>^<i>-/-</i> mice decreased mortality rate, weight loss caused by <i>C</i>. <i>sinensis</i>. by Yuru Wang (846969)

<i>Tfrc</i>^{<i>Y20H/Y20H</i>} mice have mild microcytosis and decreased iron levels at homeostasis. by Sarah K. Wideman (17118275)

The combination of CUMS and smoke exposure significantly decreased the expression of pro-apoptosis factors and increase in anti-apoptosis factors when compared to stress or smoke g... by Bai-Ping Liu (14164799)

Demographic characteristics among a representative sample of adults residing within the Agincourt Health and Socio-demographic Surveillance System from August-October 2020 in Augus... by Duduzile P. Mashinini (19173517)

Event-free survival estimate of the pulmonary arterial hypertension cohort based on the HRR1 <18 beats (n = 50) and ≥18 beats (n = 52) after a long follow-up period. by Camila Farnese Rezende (12666902)

LDL-C meta-analysis showing in (A) the overall effects of different statin types versus placebo and (B) stratified by statin treatment duration for 3-4 months and longer than 4 mon... by Solima Sabeel (9545738)

Overall CVD disease burden in DALYs attributable to 1^st-level risk factors in Chile. DALYs rates are expressed per 100,000 individuals, with a 95% uncertainty interval. by Camilo Briones-Valdivieso (21567535)

Longitudinal antibody and antigen responses to treatment vs placebo day 1–90 for nMAbs, among patients alive and with day 90 antibody and antigen measures (Sensitivity Analysis). by Elizabeth S. Munroe (21568166)

Adaptive Evolution Relieves Nitrogen Catabolite Repression and Decreases Urea Accumulation in Cultures of the Chinese Rice Wine Yeast Strain <i>Saccharomyces cerevisiae</i> XZ-11 by Weiping Zhang (311523)

“…Transcription levels of genes involved in urea metabolism were dramatically upregulated after ALE. This work describes a novel and safe strategy to improve nitrogen utilization of industrial yeast strains involved in food fermentation. …”

Adaptive Evolution Relieves Nitrogen Catabolite Repression and Decreases Urea Accumulation in Cultures of the Chinese Rice Wine Yeast Strain <i>Saccharomyces cerevisiae</i> XZ-11 by Weiping Zhang (311523)

“…Transcription levels of genes involved in urea metabolism were dramatically upregulated after ALE. This work describes a novel and safe strategy to improve nitrogen utilization of industrial yeast strains involved in food fermentation. …”