Data_Sheet_1_Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.PDF by Paloma Gómez-Fernández (6084599)

“…The IL22RA2 alternatively spliced exon was reported to be recruited through a single mutation in the proto-splice site of a Long Terminal Repeat retrotransposon sequence in the ape lineage. …”

Presentation_1_Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.pdf by Paloma Gómez-Fernández (6084599)

“…The IL22RA2 alternatively spliced exon was reported to be recruited through a single mutation in the proto-splice site of a Long Terminal Repeat retrotransposon sequence in the ape lineage. …”

Image_2_Relationship of postprandial fibroblast growth factor 21 with lipids, inflammation and metabolic dysfunction-associated fatty liver disease during oral fat tolerance test.t... by Xiaolong Li (552024)

“…</p>Results<p>Serum FGF21 significantly increased in the fasting state (P < 0.05) and showed a biphasic change of first decreasing and then increasing in MAFLD during the OFTT. …”

Data_Sheet_1_The Highs and Lows of P Supply in Medical Cannabis: Effects on Cannabinoids, the Ionome, and Morpho-Physiology.pdf by Sivan Shiponi (11136807)

“…Cannabinoid concentrations decreased linearly with increasing yield, consistent with a yield dilution effect, but the total cannabinoid content per plant increased with increasing P supply. …”

Image_1_Relationship of postprandial fibroblast growth factor 21 with lipids, inflammation and metabolic dysfunction-associated fatty liver disease during oral fat tolerance test.t... by Xiaolong Li (552024)

“…</p>Results<p>Serum FGF21 significantly increased in the fasting state (P < 0.05) and showed a biphasic change of first decreasing and then increasing in MAFLD during the OFTT. …”

DataSheet_1_Longitudinal analysis of immunocyte responses and inflammatory cytokine profiles in SFTSV-infected rhesus macaques.docx by Yi-Hui Li (11977604)

“…<p>Severe fever with thrombocytopenia syndrome virus (SFTSV), an emerging bunyavirus, causes severe fever with thrombocytopenia syndrome (SFTS), with a high fatality rate of 20%–30%. At present, however, the pathogenesis of SFTSV remains largely unclear and no specific therapeutics or vaccines against its infection are currently available. …”

Data Sheet 1_An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis.docx by Xiaolu Yang (285041)

“…</p>Conclusions<p>ASCL1 exerts oncogenic effects in BC and represents a potential therapeutic target for intervention.…”

Detection of DNA-DNA and RNA-DNA triplexes by EMSA and NMR, and molecular modeling of miRNA-duplex DNA triplex. by Steven W. Paugh (780960)

“…<p><b>(A)</b> EMSA; 5’ ROX-labeled hairpin duplex DNA (0.1 μM) was incubated for 3-hrs at 22°C in the presence (lanes 2–11) or absence (lane 1) of 2.5 μM 483-opti DNA oligo, and increasing concentration (30, 60, 150 μM) of Hoogsteen bond-optimized hsa-miR-483-5p (483-opti, lanes 3–5), hsa-miR-483-5 (483, lanes 6–8), or a scrambled RNA oligo (Scramble, lanes 9–11). …”

Data_Sheet_1_Why More Leaflets? The Role of Natural Selection in Shaping the Spatial Pattern of Leaf-Shape Variation in Oxytropis diversifolia (Fabaceae) and Two Close Relatives.do... by Hui Wang (30400)

“…We further revealed that the leaf-shape cline could largely be explained by three macroclimatic variables, with leaflet number decreasing and leaflet-blade size increasing with annual precipitation and showing the reverse trends with temperature seasonality and isothermality. …”

Table 1_Defining the end of puberty in boys: INSL3 and the acute determinants of adult Leydig-cell functional capacity.docx by Bilal Tulumcu (21428903)

“…</p>Results and discussion<p>At 17 years, mean INSL3 is not yet maximal, with high variance due to both longitudinal (timing of pubertal trajectory) and cross-sectional influences, whereas at 24 years, circulating INSL3 concentration has stabilized to its final adult status, even showing a small decreasing trend with age. Maximal INSL3 (i.e., peak puberty) was calculated to be at approximately 22 years in this cohort. …”

The Sequence-Specific Transcription Factor c-Jun Targets Cockayne Syndrome Protein B to Regulate Transcription and Chromatin Structure by Robert J. Lake (249450)

“…We found that CSB occupancy sites display a high correlation to regions with epigenetic features of promoters and enhancers. …”

DataSheet_1_Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.zip by Yan Deng (159032)

“…<p>The mechanisms underlining pathogenesis of polycystic ovary syndrome (PCOS) remain largely unknown. Dysfunction of ovarian granulosa cells plays an important role. …”

Table 3_Defining the end of puberty in boys: INSL3 and the acute determinants of adult Leydig-cell functional capacity.docx by Bilal Tulumcu (21428903)

“…</p>Results and discussion<p>At 17 years, mean INSL3 is not yet maximal, with high variance due to both longitudinal (timing of pubertal trajectory) and cross-sectional influences, whereas at 24 years, circulating INSL3 concentration has stabilized to its final adult status, even showing a small decreasing trend with age. Maximal INSL3 (i.e., peak puberty) was calculated to be at approximately 22 years in this cohort. …”

Table_1_FgMet3 and FgMet14 related to cysteine and methionine biosynthesis regulate vegetative growth, sexual reproduction, pathogenicity, and sensitivity to fungicides in Fusarium... by Feifei Zhao (153044)

“…<p>Fusarium graminearum is a destructive filamentous fungus, which widely exists in wheat and other cereal crops. …”

Table_2_Metabolic profiling and gene expression analyses provide insights into cold adaptation of an Antarctic moss Pohlia nutans.XLSX by Shenghao Liu (341236)

“…We found that proline content and several antioxidant enzyme activities were significantly increased in P. nutans under cold stress, but the contents of chlorophyll and total flavonoids were markedly decreased. A total of 559 metabolites were detected using ultra high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). …”

Table_5_Metabolic profiling and gene expression analyses provide insights into cold adaptation of an Antarctic moss Pohlia nutans.XLSX by Shenghao Liu (341236)

“…We found that proline content and several antioxidant enzyme activities were significantly increased in P. nutans under cold stress, but the contents of chlorophyll and total flavonoids were markedly decreased. A total of 559 metabolites were detected using ultra high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). …”

Data_Sheet_1_Alterations of gut microbiota are associated with brain structural changes in the spectrum of Alzheimer's disease: the SILCODE study in Hainan cohort.docx by Beiqi He (12088432)

“…Targeting the gut microbiota may be a novel therapeutic strategy for early AD.</p>…”

Syt1^M3 bladder strips are less sensitive to BoNT/B than WT bladder strips. by Hatim Thaker (7928519)

“…WT and Syt2^M3 bladder strips have decreased contractile capability, while Syt1^M3 bladders are largely resistant to the effect of BoNT/B. …”

Table 2_Defining the end of puberty in boys: INSL3 and the acute determinants of adult Leydig-cell functional capacity.docx by Bilal Tulumcu (21428903)

“…</p>Results and discussion<p>At 17 years, mean INSL3 is not yet maximal, with high variance due to both longitudinal (timing of pubertal trajectory) and cross-sectional influences, whereas at 24 years, circulating INSL3 concentration has stabilized to its final adult status, even showing a small decreasing trend with age. Maximal INSL3 (i.e., peak puberty) was calculated to be at approximately 22 years in this cohort. …”

Data_Sheet_1_An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota.PDF by Frederikke Christine Lindenberg (10837854)

“…Blood sampled from the foals in the test group on Day 7, 28, and 49 showed non-significant increases in IgA, and decreases in IgG on Day 49. In BALB/cBomTac mice inoculated with gut microbiota from test and control foals we found increased species richness, increased relative abundance of several species identified as potentially anti-inflammatory in horses, which were unclassified Clostridiales, Ruminococcaceae, Ruminococcus, Oscilospira, and Coprococcus. …”