Wnt Signaling Regulates the Lineage Differentiation Potential of Mouse Embryonic Stem Cells through Tcf3 Down-Regulation by Yaser Atlasi (409447)

“…We found that <i>Tcf3</i> down-regulation in the context of constitutively active Wnt signaling does not result from promoter DNA methylation but is likely to be caused by a plethora of mechanisms at both the RNA and protein level as shown by the observed decrease in activating histone marks (H3K4me3 and H3-acetylation) and the upregulation of miR-211, a novel Wnt-regulated microRNA that targets Tcf3 and attenuates early neural differentiation in mouse ESCs. …”

TSA reduces hESC motility and limits trophoblast outgrowth and invasion. by Carlos Estella (149879)

“…The invasion area was identified by the absence of stromal cells (red) and outlined by a white line. Bar size is 50 µm. <b>D</b>, 1 µM TSA-treated hESCs significantly decreased the area of embryo spreading. …”

Image_1_Inulin accelerates weight loss in obese mice by regulating gut microbiota and serum metabolites.tif by Zeang Wu (13872479)

“…However, the mechanisms involved were still largely unknown. Sixteen high-fat diets (HFDs)-induced obese C57BL/6 mice were converted to a normal diet and then randomized into two groups, OND (obese mice + normal diet) group gavage-fed for 10 weeks with normal saline and ONDI (obese mice + normal diet + inulin) group with inulin at 10 g/kg/day. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…<p>(<b>A</b>) Cross breading of <i>Tra2b^fl/fl</i> with <i>Tra2b^fl/+; Nestin-Cre^tg/0</i> mice allowed generation of neuronal-specific knock-out (KO) animals as well as controls (CRTL) and heterozygous knock-out animals (HET) in one litter. …”

Image_2_Inulin accelerates weight loss in obese mice by regulating gut microbiota and serum metabolites.tif by Zeang Wu (13872479)

“…However, the mechanisms involved were still largely unknown. Sixteen high-fat diets (HFDs)-induced obese C57BL/6 mice were converted to a normal diet and then randomized into two groups, OND (obese mice + normal diet) group gavage-fed for 10 weeks with normal saline and ONDI (obese mice + normal diet + inulin) group with inulin at 10 g/kg/day. …”

Image_3_Inulin accelerates weight loss in obese mice by regulating gut microbiota and serum metabolites.tif by Zeang Wu (13872479)

“…However, the mechanisms involved were still largely unknown. Sixteen high-fat diets (HFDs)-induced obese C57BL/6 mice were converted to a normal diet and then randomized into two groups, OND (obese mice + normal diet) group gavage-fed for 10 weeks with normal saline and ONDI (obese mice + normal diet + inulin) group with inulin at 10 g/kg/day. …”

DataSheet_1_Preoperative immunological plasma markers TRAIL, CSF1 and TIE2 predict survival after resection for biliary tract cancer.pdf by Hannes Jansson (16390068)

“…The aim of this study was to evaluate specific immunologic prognostic markers and immune responses by analyzing preoperative plasma samples from a large prospectively collected biobank.</p>Methods<p>Expression of 92 proteins representing adaptive and innate immune responses was investigated in plasma from 102 patients undergoing resection for BTC 2009-2017 (perihilar cholangiocarcinoma n=46, intrahepatic cholangiocarcinoma n=27, gallbladder cancer n=29), by means of a high-throughput multiplexed immunoassay. …”

DataSheet_1_Preoperative immunological plasma markers TRAIL, CSF1 and TIE2 predict survival after resection for biliary tract cancer.pdf by Hannes Jansson (16390068)

“…The aim of this study was to evaluate specific immunologic prognostic markers and immune responses by analyzing preoperative plasma samples from a large prospectively collected biobank.</p>Methods<p>Expression of 92 proteins representing adaptive and innate immune responses was investigated in plasma from 102 patients undergoing resection for BTC 2009-2017 (perihilar cholangiocarcinoma n=46, intrahepatic cholangiocarcinoma n=27, gallbladder cancer n=29), by means of a high-throughput multiplexed immunoassay. …”

Video2_Detection of Inhomogeneity After Mixing Solutions by Analyzing the Chemical Wave Pattern in the Belousov-Zhabotinsky Reaction.MP4 by Yasunao Okamoto (7535402)

“…A one-dimensional chemical wave appeared for large inhomogeneity in mixing. …”

Video1_Detection of Inhomogeneity After Mixing Solutions by Analyzing the Chemical Wave Pattern in the Belousov-Zhabotinsky Reaction.MP4 by Yasunao Okamoto (7535402)

“…A one-dimensional chemical wave appeared for large inhomogeneity in mixing. …”

Amiloride-sensitive channels in type I fungiform taste cells in mouse-1 by Aurelie Vandenbeuch (96031)

“…The I-V plot is represented (n = 52 cells; mean ± sem). B: Other cells (46%) exhibit outward Kand inward Nacurrents, but lack a voltage-dependent Ca(Ba) current. …”

Influence of amphibian presence on the intensity of luring behavior. by Gil Wizen (204764)

“…As the distance between the amphibian and larva decreased from 15 to 1 cm, the intensity of luring movements in the test group (filled circles) almost doubled (solid line; mean ± SE, 2.8±0.47 and 4.9±0.69 movements/min, respectively). …”

Cardiac properties in long term mdx mice. by Kevin J. Morine (188404)

“…<p>(a) Protein levels of the activin IIB receptor were similar in the <i>mdx</i> heart and quadriceps. …”

Heat- and acid-resistant endotoxin neutralization (HAREN). by Keith Champion (425578)

“…<p>Each data point with error bar represents the average and standard deviation of 3 replicates. The mean and standard error of the mean are indicated for each sample group. …”

<strong>Supplementary Figure 3.</strong>  by Muhammad Aslam (6598628)

“…Proteomic data from the three separate colon organoid cultures from three subjects (analyzed in Supplement Figure 2) were merged to obtain mean values and re-analyzed. <u>A</u>: Bar graph showing proteins (merged data) increased or decreased by an average of 1.8-fold or greater with each of the three interventions compared to the control. …”

Amiloride-sensitive channels in type I fungiform taste cells in mouse-6 by Aurelie Vandenbeuch (96031)

“…The I-V plot is represented (n = 52 cells; mean ± sem). B: Other cells (46%) exhibit outward Kand inward Nacurrents, but lack a voltage-dependent Ca(Ba) current. …”

<i>B. parapertussis</i> is more susceptible to wP–induced immunity in the absence of O-antigen. by Xuqing Zhang (144598)

“…<p>Groups of four naïve (black) or wP vaccinated (white) C57BL/6 mice were challenged with the indicated bacteria. (A) The number of CFUs recovered from the respiratory tract on day 3 post-challenge is expressed as the Log₁₀ mean ± the standard error. …”

Genome-Wide Association of Stem Water Soluble Carbohydrates in Bread Wheat by Yan Dong (135314)

“…Liner regression showed a clear dependence of WSC BLUE scores on numbers of favorable (increasing WSC content) and unfavorable alleles (decreasing WSC), indicating that genotypes with higher numbers of favorable or lower numbers of unfavorable alleles had higher WSC content. …”

Table_1_The Longitudinal Impact of Maternal Depression and Neighborhood Social Context on Adolescent Mental Health.DOCX by Daphne Lew (6439874)

“…Primary analyses were conducted using multi-trajectory modeling and linear regressions.</p>Results<p>Five multi-trajectories were identified, two of which were characterized by no MD but either high or low NCE, and three of which were characterized by similarly moderate levels of NCE but either increasing, decreasing, or consistently high MD. …”

Table_3_Animal Breed Composition Is Associated With the Hindgut Microbiota Structure and β-Lactam Resistance in the Multibreed Angus-Brahman Herd.XLSX by Peixin Fan (5527055)

“…As the first study aimed at understanding changes in hindgut microbiota among beef cattle with linear gradient of breed composition and its association with marbling in meat, our results suggest that the effects of animal genetics on the gut microbiota structure is associated with fat deposition and potentially a factor affecting the gut antimicrobial resistance.…”