Forelimb deformity and pull strength changes after treatment with edaravone and vehicle. by Ken Ikeda (814130)

“…Results are represented as the mean ± SEM (n = 10/group). (B) Vehicle-treated mice decreased forelimb strength gradually. …”

Effects of astragaloside IV on proliferation and cytokine secretion of CD4+ T cells. by Yixin He (466799)

“…<p>A, ASI did not prevent proliferation of CD4+ T cells isolated from EAE mice. …”

Data reported at baseline and at follow-up, n = 76. by Wen-Hung Huang (138307)

“…</p><p>Abbreviations: LS-BMD, lumbar spine bone mineral density; H-BMD, hip bone mineral density; FN-BMD, femoral neck bone mineral density; T, number of standard deviations (SD) above or below the mean value of a sex-matched, young adult mean of BMD. …”

Open field test. by Jaume F. Lalanza (509747)

“…The data are given as the mean ± SEM (n = 8). The CAF diet decreased the distance travelled (<i>p</i><0.01) and increased time in the centre (<i>p</i><0.01; diet effect in the two-way ANOVA). …”

Gene expression variability for multiple-parameter fluctuations. by Abhyudai Singh (503811)

“…Other model parameters taken as mRNA half-life = 2 hours, protein half-life = time-scale of parameter fluctuations = 10 hours, mean transcriptional burst size = 10 and mean mRNA copy number per cell = 50.…”

MMP-9 and MMP-8 levels in protracted ARDS. by Michele Y. F. Kong (346852)

“…B: Decline in MMP-8 levels with ARDS progression. Total MMP-8 decreased with ARDS progression in those who remained intubated for >5 days (n = 25, mean±SEM 1245±343 ng/mg at 48 hrs vs. 537±122 ng/mg at day 6, respectively; *<i>p<0.05</i>).…”

Meta-analysis of 3 manipulations of the insulin/Tor signaling identifies rover-biased genes. by Clement F. Kent (260706)

“…<p>Three published studies decreased insulin/Tor effects via (A) ablation of <i>dilp3</i> expressing cells <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Buch1" target="_blank">[28]</a>, (B) overexpression of constitutively active <i>foxo </i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Gershman1" target="_blank">[29]</a>, or (C) rapamycin <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Guertin1" target="_blank">[30]</a>. …”

Data_Sheet_2_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Sapanisertib-alone in canine plasma following single 0.1 mg/kg dose [mean C_max 26.3 ng/mL (21%CV), median T_max 2.0 hr, and mean AUC 248 hr^*ng/mL (41%CV)] resembled levels in human therapeutic trials; whereas canine sapanisertib exposure was reduced when combined with trametinib, a known cytochrome P450 CYP3A4 inducer. …”

Data_Sheet_1_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Sapanisertib-alone in canine plasma following single 0.1 mg/kg dose [mean C_max 26.3 ng/mL (21%CV), median T_max 2.0 hr, and mean AUC 248 hr^*ng/mL (41%CV)] resembled levels in human therapeutic trials; whereas canine sapanisertib exposure was reduced when combined with trametinib, a known cytochrome P450 CYP3A4 inducer. …”

DataSheet_1_Pro- and Anti-Inflammatory Responses in Severe COVID-19-Induced Acute Respiratory Distress Syndrome—An Observational Pilot Study.docx by Quirin Notz (4269991)

“…The B cell system was largely unimpeded. This coincided with a slight increase in anti-SARS-CoV-2-Spike-RBD immunoglobulin (Ig) G and a decrease in anti-SARS-CoV-2-Spike-RBD IgM. …”

Influence of GLP-1 on Myocardial Glucose Metabolism in Healthy Men during Normo- or Hypoglycemia by Michael Gejl (506066)

“…</p><p>Results</p><p>In the normoglycemia study mean (± SD) age was 25±3 years, and BMI was 22.6±0.6 kg/m² and in the hypoglycemia study the mean age was 23±2 years with a mean body mass index of 23±2 kg/m². …”

<i>sod-2</i> Deletion Alters the Lifespan of Extended Longevity Mitochondrial Mutants. by Jeremy M. Van Raamsdonk (267436)

“…E) <i>sod-2</i> deletion extends mean but not maximum lifespan of <i>glp-1</i> worms (germ-line ablation). …”

miRNA expression is altered in NSCs from diabetic pregnancy. by Sukanya Shyamasundar (420641)

“…(C) miRNA expression analysis revealed decreased expression of miRNAs mmu-miR-200a, mmu-miR-200b, mmu-miR-466a-3p and mmu-miR-466d-3p in NSCs from diabetic pregnancy (open bars) when compared to the control (filled bars). …”

Tify can calculate image scores which correlate well with human scoring. by Dean Philip John Kavanagh (6444464)

“…Each point represents a single user, and the solid line represents the mean of these values. …”

The perceived directions of the dual barber poles in which the wavelength of the two component barber poles differed. by Li-Ting Huang (416359)

“…The probability the subject perceived a global percept instead of two individual component barber poles moving at different velocities observed in an example subject (B) and in the mean across subjects (C). …”

Overexpression of estrogen receptor-α inhibited the production of terminally arrested progeny. by Mine Mumcuoglu (246981)

“…<p>(<b>A</b>) ER-overexpressing (ER-5, ER-7, ER-26) and control (C-8, C-10, C-11) clones were established from T47D cells and tested for ER expression by western blotting using decreasing amounts of total proteins. …”

Supplementary Material for: Recent Practice Patterns and Variations in Children Hospitalized for Asthma Exacerbation in Japan by Okubo Y. (9550811)

“…Mixed-effect generalized linear models were used to investigate the treatment trends. …”

TOP1α and UPF1 directly repress <i>TTG2</i>. by Chengxiang Li (5278343)

“…<p>(A) <i>TTG2</i> expression in pistils (left panel) or pollens (right panel) in different genetic backgrounds. …”

<i>P. aeruginosa</i> T3SS needle tip complex protein PcrV increases PMVEC permeability associated with cell damage during late phase infection. by Jonathon P. Audia (490529)

“…PMVECs were inoculated with medium alone, saline solution (vehicle control), or with either <i>P. aeruginosa</i> mutant at a 40:1 MOI. Inoculation with PA103 (ΔU/ΔT) caused significant increases in PMVEC permeability (i.e., decreased electrical resistance) compared to no treatment (medium alone), vehicle control inoculation, or inoculation with PA103 (ΔPcrV). …”

Protective effects of Dll4-modulated dendritic cells on airway hyper-responsiveness and airway inflammation. by Huei-Mei Huang (403472)

“…Results are expressed as the mean ± SEM of 5 to 7 mice in each group. (C–G) Dll4-modulated DCs decreased the levels of inflammatory mediators in bronchoalveolar lavage fluid (BALF). …”