Mutation of the hydrophobic tip residues disrupts evoked transmitter release. by Matthew R. Bowers (8423115)

“…<p>The single hydrophobic mutation decreased neurotransmitter release by 50% while the double mutation inhibited release to a greater extent than that seen in <i>syt^null</i> mutants. …”

Supplementary Material for: Retinocytoma: clinical and genetic characteristics in 16 pediatric and adult cases by figshare admin karger (2628495)

“…Age at diagnosis ranged from 11 months to 75 years (mean 28.1 years). Thirteen cases were asymptomatic, while three presented with floaters, decreased visual acuity, or strabismus. …”

The number of primary care visits among children younger than 20 years of age per calendar-month from 1 January 2005 to 31 December 2015. by Elias Eythorsson (5820515)

“…Panels B and C suggest that the number of both AOM visits and all other visits decreased in the post-vaccine period, and that AOM visits decreased to a larger degree.…”

Molecular Magnetism of M₆ Hexagon Ring in <i>D</i>_3<i>d</i> Symmetric [(MCl)₆(XW₉O₃₃)₂]^12– (M = Cu<sup>... by Toshihiro Yamase (1265778)

“…The strongest ferromagnetic coupling for the Cu₆ hexagon of <b>2</b>, the structure of which approximately provides the Cu₆(μ₃-O)₁₂ cylindrical geometry, is demonstrated by the polarization mechanism based on the point-dipole approximation, which provides a decrease of the ferromagnetic interaction due to the out-of-cylinder deviation of the Cu atoms for <b>1</b>. …”

Molecular Magnetism of M₆ Hexagon Ring in <i>D</i>_3<i>d</i> Symmetric [(MCl)₆(XW₉O₃₃)₂]^12– (M = Cu<sup>... by Toshihiro Yamase (1265778)

“…The strongest ferromagnetic coupling for the Cu₆ hexagon of <b>2</b>, the structure of which approximately provides the Cu₆(μ₃-O)₁₂ cylindrical geometry, is demonstrated by the polarization mechanism based on the point-dipole approximation, which provides a decrease of the ferromagnetic interaction due to the out-of-cylinder deviation of the Cu atoms for <b>1</b>. …”

GLA and SDA are required for survival against <i>P. aeruginosa</i>. by Madhumitha Nandakumar (269242)

“…Mean time to death relative to wild-type (mutant TD_mean / wild-type TD_mean) on <i>P. aeruginosa</i> (PA14) is shown: Values greater than 1 indicate extended survival on PA14, while values less than one indicate decreased survival relative to wild-type. …”

Ternary diagrams for major test structure categories of Loeblich & Tappan (1984) [52]. by Alexander F. Humphreys (5742746)

“…<p>(A) average compositions of foraminifera from each sampled island, including mean pH (red) and mean Fisher α indices (blue), revealing a general increase in hyaline forms along declining pH and Fisher α indices gradients as well as shift toward higher agglutinated content at Española, Santa Fé and Isabela islands with decreasing pH (circled). …”

d-Amino-levulinic acid (d-ALA) does not alter 8-azido-ATP-[γ]-biotin photolabeling in ABCB10, whereas GSH and GSSG do. by Wei Qiu (217045)

“…The bar graph shows the relative intensity of ExtrAvidin-HRP as mean ± SD of independent experiments. B) and C) Increasing concentrations of GSH or GSSG decreased the biotin signal during the photolabeling of ABCB10 by 8-azido-ATP [γ] biotin. …”

Model validation. by Erwin P. Gianchandani (263178)

“…See <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000403#pcbi.1000403.s004" target="_blank">Dataset S4</a> for a legend describing the placement of the genes within this panel. …”

Genetic Architecture of Intrinsic Antibiotic Susceptibility by Hany S. Girgis (263914)

“…</p><h3>Conclusions/Significance</h3><p>Our results illustrate that a wide-range of mutations can modulate the activity of many cellular resistance processes and demonstrate that <em>E. coli</em> has a large mutational target size for increasing antibiotic tolerance. …”

Data_Sheet_1_Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.zip by Jia Cui (296670)

“…Recently, ASAP1 polymorphisms have been reported to be associated with human susceptibility to tuberculosis (TB) according to a large-scale genome-wide association study (GWAS); ASAP1 expression affects dendritic cell migration, which may be involved in TB predisposition. …”

Data_Sheet_1_Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.docx by Jia Cui (296670)

“…Recently, ASAP1 polymorphisms have been reported to be associated with human susceptibility to tuberculosis (TB) according to a large-scale genome-wide association study (GWAS); ASAP1 expression affects dendritic cell migration, which may be involved in TB predisposition. …”

Genome-Wide Analysis of Selective Constraints on High Stability Regions of mRNA Reveals Multiple Compensatory Mutations in <i>Escherichia coli</i> by Yuanhui Mao (138418)

“…<div><p>Message RNA (mRNA) carries a large number of local secondary structures, with structural stability to participate in the regulations of gene expression. …”

Data_Sheet_1_Enhancing comfort of resident physicians treating adults with intellectual and developmental disabilities by facilitating meaningful interactions.docx by Jessica Solomon Sanders (18588091)

“…</p>Results<p>53 residents completed both pre- and post-conference surveys. Mean IDP scores decreased from 78.7 (10.9) to 75.8 (9.5; p < 0.01), indicating decreasing discomfort. …”

Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways by David E. Shore (123998)

“…These data demonstrate that induction of cytoprotective pathways is central to longevity extension and identify a large set of new genetic components of the pathways that detect cellular damage and couple that detection to downstream cytoprotective effectors.…”

Targeted deletion of PPARγin macrophages inhibits lung cancer metastasis in an orthotopic mouse model of non-small cell lung cancer. by Howard Li (194066)

“…Lungs from PPARγ-Mac^neg mice on control chow showed a statistical decrease in arginase I positive cells; pioglitazone increased the number of these cells to levels seen in PPARγ^flox/flox mice. …”

Hhat KD inhibits Hh-mediated juxtacrine/paracrine signaling. by Antonios D. Konitsiotis (532086)

“…<p>A. Hhat-#2 siRNA KD in A549 cells was assessed by qPCR 24–96 h after siRNA transfection showing 20–60% decrease in Hhat mRNA expression. …”

Validation of pigmentation candidate genes using Exelixis insertion mutants and RNAi knockdown. by Lauren M. Dembeck (733382)

“…<p>The <i>y</i>-axis in all panels is the deviation of the appropriate control line mean from the experimental line mean. Increases and decreases in the proportion of melanization are given above and below the <i>x</i>-axis, respectively. …”

Deep White Matter in Huntington's Disease by Owen Phillips (453524)

“…Fractional anisotropy decreased between the Pre-HD and HD phase and AD/RD increased and although impairment was pervasive in HD, degeneration occurred in a pattern in Pre-HD. …”

Do phytoplankton and epiphyton communities differ between organic and conventional rice fields? by Ana Paula Vestena Cassol (4679932)

“…Cyanobacteria and Chlorophyceae comprised a large proportion of the epiphytic density in CF and OF, respectively. …”