Glycolytic inhibitor 2-DG alters downstream AMPK and mTOR signaling, and neuronal gene expression, but does not affect Wnt signaling. by Roaya S. Alqurashi (11243136)

“…<p>(A) SE-induced Wnt signaling and Warburg metabolic enzyme PKM2 are unaffected by 2DG. …”

The effect of storage at -20°C on the ability of α₂M to bind to SH-SY5Y cells. by Amy R. Wyatt (759221)

“…(C) Flow cytometry analysis showing the binding of α_<b>2</b>M preparations stored as described in (A) to SH-SY5Y cells. The results shown are the composite geometric mean values of FITC fluorescence for 5000 viable cells (n = 3 ± SD) in AFU and are adjusted for background fluorescence. * Denotes significant increases in cell surface binding of α_<b>2</b>M stored at -20°C compared to a batch matched sample stored at 4°C. v Denotes significant decreases in cell surface binding of α_<b>2</b>M as a result of pre-incubation of the cells with RAP.…”

Optical coherence tomography and thickness measurements. by Andreas Ebneter (702819)

“…<p>(<b>A</b>) Mean total retinal thickness (means±SEM) over 4 weeks. …”

AntagomiR-365 inhibits tumorgenesis and restores NFIB expression both <i>in vitro</i> and <i>in vivo</i>. by Meijuan Zhou (581065)

“…Relative tumor volumes are shown with respect to day 7. Data are plotted as mean ± S.E. (D) AntagomiR-365 injection drastically decreased the expression levels of the miR-365 in xenografts and thus led to the up-regulation of NFIB and p53 and down-regulation of CDK6 and Bcl-2. …”

Caribbean Sea palaeoceanographic proxy records from ODP Site 999 between 3.400 and 3.180 Ma. by Stijn De Schepper (496614)

“…All circles with white fill are data from this study. (A) Palaeomagnetic reversals; (B) benthic isotope age model for Site 999 tuned to the LR04 stack <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0081508#pone.0081508-Lisiecki1" target="_blank">[10]</a> (black line); (C) sea level estimates; (D) SST­_Mg/Ca of <i>G. sacculifer</i>, thick black line represents 4-point running mean, shading represents calibration error; (E) δ¹⁸O_sw-ice estimate of salinity; (F) carbonate-sand fraction, filled black circles are data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0081508#pone.0081508-Haug1" target="_blank">[27]</a>, thick line represents 4-point running mean. …”

Invasive behavior of transformed cell lines. by Svetlana N. Rubtsova (775149)

“…The diagram shows the percentage of transformed cells that invaded the IAR-2 monolayer and spread on the glass substrate below the monolayer to the number of seeded cells at various time points (mean ± SEM, n = 40). Transfection of a dominant-negative mutant of E-cadherin dramatically decreased the invasion of the epithelial monolayer by transformed cells. …”

Caffeine metabolism in <i>Drosophila melanogaster</i> and the influence of cytochrome P450 inhibitor. by Alexandra Coelho (691773)

“…<p>A- Separation of non-radiolabeled standards of caffeine and metabolites (lane 1) with a homogenate of wild-type four-days-old <i>Drosophila</i> male flies (w¹¹¹⁸) exposed with radiolabeled caffeine for 2 hours (lane 2) on thin layer chromatography. …”

SIRT3 controls intracellular ROS levels. by Xingxing Kong (363056)

“…C₂C₁₂ myotubes were treated with the indicated adenovirus (Ad-siControl, Ad-siPGC-1α or Ad-siSIRT3), treated with DHE, and analyzed with a flow cytometry as described in panel A. <b>C</b>, Overexpression of PGC-1α decreased cellular ROS level, and knockdown of SIRT3 blocked the inhibitory effect of PGC-1α on ROS production. …”

Amilorides, but not OLC15, reduced the phasic bombykal (BAL)-dependent action potential (AP) response Zeitgebertime-dependently. by Andreas Nolte (409768)

“…(A,B) Bin size = 10 ms. Mean ± SEM (dotted line). …”

Elicitation of the hippocampal theta by the stimuli. by Keita Tokuda (5661373)

“…(A) A representative LFP signal around a presentation of the light cue. …”

The catalytic activity of cPLA₂α is required to support intra-Golgi transport. by Enrica San Pietro (259862)

“…This signal increased after ionomycin treatment (J), but decreased after pyrrolidine addition (K), as also revealed by quantification (L) of the mean fluorescence per cell (mean±SD; <i>n</i> = 20 cells). …”

Gangliosides are required for viral capture mediated by mDC. by Nuria Izquierdo-Useros (91232)

“…Data show mean values and standard error of the mean (SEM) from five independent experiments including cells from at least six donors. mDCs capture significantly higher amounts of GM3-containing LUV_HIV-tRed than Cer or Ø LUV_HIV-tRed (<i>p</i><0.0001, paired <i>t</i> test). mDCs capture significantly higher amounts of GM1a-containing LUV_HIV-tRed than negatively charged PS-LUV_HIV-tRed (<i>p</i> = 0.0081, paired <i>t</i> test). …”

Percentages of lipids present in serum per mouse plotted for quercetin mice to control mice. by Elise F. Hoek-van den Hil (286753)

“…TG were significantly decreased by the quercetin diet. Data is presented as mean ± SEM. …”

Antibiotics impairs intestinal barrier function. by Yanhai Feng (6852881)

“…<p>A. Intestinal permeability to 4.4 kDa FITC-dextran was significantly increased after antibiotics treatment. …”

ROCK inhibitor Y-27632 on the morphology and growth of porcine trophoblast cells. by Dongxia Hou (566461)

“…<p>(A) Dome structure formed after cultured with Y-27632. …”

Table_1_Evolutionary trade-offs constraining the MHC gene expansion: beyond simple TCR depletion model.xlsx by Magdalena Migalska (4227874)

“…We found a non-linear relationship between MHC diversity and T cell proportions (with intermediate MHC numbers coinciding with the largest T cell proportions), perhaps reflecting an optimality effect of balanced positive and negative thymic selection. …”

Image 1_Association of self-reported sleep duration with leukocyte telomere length in type 2 diabetes mellitus patients.tiff by Liqun Wang (426945)

“…Restricted cubic splines (RCS) analysis was initially performed to evaluate the potential nonlinear relationship between sleep duration and LTL. Subsequently, a multiple mixed-effect linear regression model was utilized to examine this association.…”

Image_1_Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome.pdf by Juliana Imgenberg-Kreuz (7055936)

“…Analysis of differential methylation between SLE and pSS identified 2,244 DMCs with a majority of sites showing decreased methylation in SLE compared to pSS. …”

Table_1_Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome.pdf by Juliana Imgenberg-Kreuz (7055936)

“…Analysis of differential methylation between SLE and pSS identified 2,244 DMCs with a majority of sites showing decreased methylation in SLE compared to pSS. …”

Impact of 8 months of exercise on aging-related decline in locomotor activity from 18–27 months old. by Jennifer C. Arnold (4621795)

“…(round by round outcome; round 5 (t = 2.44, *<i>p</i> = 0.016), round 6 (t = 1.19, ns), round 7 (t = 1.16, ns), round 8 (t = 1.75, ns). <b>B.</b> Linear regression analysis of aging-related decreases in locomotor activity (combined movement number and horizontal activity results) against baseline in non-exercise vs exercise groups out to 27 months of age. …”