Table1_Mechanisms of Anergic Inflammatory Response in Nasopharyngeal Carcinoma Cells Despite Ubiquitous Constitutive NF-κB Activation.DOCX by Xiaoying Zhou (119401)

“…We found that NF-κB was largely trapped in lipid droplets (LDs) in the cytoplasm of the NPC-derived cells, while the increased expression of lysine-specific histone demethylase 1 (LSD1, a repressive nuclear factor) reduces the response mediated by remaining NF-κB at the promoters responding to inflammatory stimuli. …”

Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver by Sunmi Seok (3434741)

“…Hepatic miR-802 levels are increased in FXR-knockout (KO) or SHP-KO mice and are decreased by activation of FXR in a SHP-dependent manner. …”

Table 1_The immune receptor XA21 causes semi-male sterility and grain loss in rice.xlsx by Beatriz de Toledo Franceschi (22589708)

“…Here, we demonstrate that Xa21 expression causes drastic fertility defects, including reduced pollen viability, impaired anther dehiscence, and severe grain loss, at a low temperature (24°C) and in a dose-dependent manner. …”

Image_4_Reg-1α Promotes Differentiation of Cortical Progenitors via Its N-Terminal Active Domain.TIF by Marjorie Varilh (1488712)

“…Reg-1α and Extl3 genes are expressed in the developing cortex but their expression decreases in adulthood, pointing to a possible function of this signaling system at the early developmental stages. …”

DataSheet_1_Intracellularly Localized PIN-FORMED8 Promotes Lateral Root Emergence in Arabidopsis.pdf by Hyodong Lee (8380254)

“…However, the role of short hydrophilic loop PINs (short PINs) in organogenesis is largely unknown. In this study, we investigated the role of a short PIN, PIN8, in lateral root (LR) development in Arabidopsis thaliana. …”

Table 2_The immune receptor XA21 causes semi-male sterility and grain loss in rice.xlsx by Beatriz de Toledo Franceschi (22589708)

“…Here, we demonstrate that Xa21 expression causes drastic fertility defects, including reduced pollen viability, impaired anther dehiscence, and severe grain loss, at a low temperature (24°C) and in a dose-dependent manner. …”

Table_2_BAG3 Suppresses Loading of Ago2 to IL6 mRNA in Pancreatic Ductal Adenocarcinoma.xlsx by Chao Li (145513)

“…BAG3 is correlated with poor prognostics in patients with pancreatic ductal adenocarcinoma (PDAC), however, the exact mechanisms remain largely unknown. In this study, we demonstrated that BAG3 downregulation decreased IL6 release by PDACs, and IL6 reduction was, at least partially, responsible for suppression of PSCs activation by PDACs with BAG3 downmodulation. …”

Genetics, Synergists, and Age Affect Insecticide Sensitivity of the Honey Bee, <i>Apis mellifera</i> by Frank D. Rinkevich (107592)

“…While the causes of these losses are numerous and the interaction between them is very complex, the role of insecticides has garnered much attention. As a result, there is a need to better understand the risk of insecticides to bees, leading to more studies on both toxicity and exposure. …”

Members of the <i>RAD52</i> Epistasis Group Contribute to Mitochondrial Homologous Recombination and Double-Strand Break Repair in <i>Saccharomyces cerevisiae</i> by Alexis Stein (822633)

“…We have determined that both Rad51p and Rad59p are localized to the matrix of the mitochondria and that Rad51p binds directly to mitochondrial DNA. In addition, a mitochondrially-targeted restriction endonuclease (mtLS-<i>Kpn</i>I) was used to produce a unique double-strand break (DSB) in the mitochondrial genome, which allowed direct analysis of DSB repair <i>in vivo</i> in <i>Saccharomyces cerevisiae</i>. …”

ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance by Kun Liu (148201)

“…<p>Pluripotent stem cells, including induced pluripotent and embryonic stem cells (ESCs), have less developed mitochondria than somatic cells and, therefore, rely more heavily on glycolysis for energy production.<a href="#cit0001 cit0002 cit0003" target="_blank">^1-3</a> However, how mitochondrial homeostasis matches the demands of nuclear reprogramming and regulates pluripotency in ESCs is largely unknown. …”

Image_3_Reg-1α Promotes Differentiation of Cortical Progenitors via Its N-Terminal Active Domain.TIF by Marjorie Varilh (1488712)

“…Reg-1α and Extl3 genes are expressed in the developing cortex but their expression decreases in adulthood, pointing to a possible function of this signaling system at the early developmental stages. …”

Table_1_Fibroblast Growth Factor-1 Improves Insulin Resistance via Repression of JNK-Mediated Inflammation.docx by Lei Fan (166139)

“…<p>Insulin resistance is associated with a greatly increased risk of type 2 diabetes. Administration of fibroblast growth factor-1 (FGF-1) resulted in a marked improvement in insulin sensitivity. …”

Understanding human and nature interaction outcomes for sustaining tourist destinations: An example of Jiuzhaigou Nature Reserve, China by Guiping Deng (8947835)

“…We then summarized such interactions and their resulted environmental conditions in a time sequence. Human activities have changed Jiuzhaigou system from largely human-nature balanced to partially degraded, and then to recovered and intensively managed system during the past six decades. …”

DataSheet1_Transcriptome and metabolome comprehensive analysis reveal the molecular basis of slow-action and non-repellency of cycloxaprid against an eusocial pest, Solenopsis invi... by Chengju Du (14639189)

“…<p>The eusocial pest, red imported fire ant (Solenopsis invicta), is a highly invasive species that poses significant threats to public safety, agriculture, and the ecological environment. …”

Data_Sheet_1_Biomarkers in Ringed Seals Reveal Recent Onset of Borealization in the High- Compared to the Mid-Latitude Canadian Arctic.docx by Camille de la Vega (3170718)

“…Specifically, over the past 25 years, the trophic position of ringed seals from the mid-Arctic was largely constant, whereas the trophic position of ringed seals decreased in the high-Arctic, reaching similar values observed in the mid-Arctic in 2015–2016. …”

Table_2_Osmoregulation in Barnacles: An Evolutionary Perspective of Potential Mechanisms and Future Research Directions.DOCX by Kristina Sundell (1555405)

“…Tolerance to low salinities may play a crucial role in determining future distributions of barnacles since forthcoming climate-change scenarios predict decreased salinity in shallow coastal areas. …”

Trajectories of Antidepressant Medication before and after the Onset of Unemployment by Subsequent Employment Experience by Taina Leinonen (569819)

“…During unemployment medication decreased in all groups except among the intermittently unemployed. …”

Coupling of RNA polymerase III assembly to cell cycle progression in <i>Saccharomyces cerevisiae</i> by Marta Płonka (6333026)

“…<i>rpc128-1007</i> is associated with defective assembly of Pol III complex and, in consequence, decreased level of tRNA synthesis. Here, we show that <i>rpc128-1007</i> mutant cells remain largely unbudded and larger than wild type cells. …”

miR136 regulates proliferation and differentiation of small tail han sheep preadipocytes by Man Luo (105740)

“…Bioinformatics and biochemical validation manifested that PPARGC1B was a target of miR136. Furthermore, miR136 mimics decreased PPARγ and C/EBPα expression accompanied by PPARGC1B expression descending. …”

Chloride Secretion Induced by Rotavirus Is Oxidative Stress-Dependent and Inhibited by <i>Saccharomyces boulardii</i> in Human Enterocytes by Vittoria Buccigrossi (190661)

“…These results suggest a link between oxidative stress and RV-induced diarrhea. …”