Comparison of substrate metabolism in brown and white preadipocytes and adipocytes. by Barry R. Bochner (226699)

“…<p>Normalized optical-density scores representing nutrient metabolism, showing the greatest differences between white fat (top) and brown fat (bottom) cells in either an undifferentiated (gray bars) or differentiated (black bars) state. Included are a) wells that cause no change (1, negative control), b) nutrients that are high in brown preadipocytes and decrease upon differentiation (2, α-D-glucose-1-phosphate; 3, D-glucose-6-phosphate; 4, D-fructose-6-phosphate; 5, glycogen), c) a similarly behaved nutrient that is high in white fat (6, hexanoic acid), d) nutrients that decrease during differentiation of both cell types (7, dextrin; 8, butyric acid), and e) nutrients that increase upon white fat differentiation (9, L-leucine; 10, Leu-Leu; 11, succinamic acid, 12. acetoacetic acid). …”

The fPCs, their gene specific scores, and the discriminating boundary explain changing collective phasing in double mutants. by Leo Zeitler (13775500)

“…Whilst <i>isw2</i>Δ<i>chd1</i>Δ and <i>isw1</i>Δ<i>isw2</i>Δ require both fPCs to linearly separate the Pearson clusters, <i>rsc8chd1</i>Δ is almost exclusively dependent on the second fPC, which means this mutant decreased the slope tilt. …”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…Every neuron examined (n = 16) showed a decrease in depolarization from baseline (population mean was a 103.3% decrease, standard deviation 14.1%). …”

Data_Sheet_1_Sleep-Disordered Breathing Is Associated With Reduced Left Atrial Strain Measured by Cardiac Magnetic Resonance Imaging in Patients After Acute Myocardial Infarction.d... by Michael Wester (7359473)

“…Patients with improved SDB (ΔAHI < −5/h) exhibited a mean improvement of LA reservoir strain of +7.2 ± 8.4% whereas patients with SDB deterioration (ΔAHI> + 5/h) showed a mean decrease of −5.3 ± 11.0% (p = 0.0131). …”

Soluble plantain NSP increases the transmucosal short circuit current of <i>ex vivo</i> human ileal follicle-associated epithelium. by Bryony N. Parsons (469436)

“…<p>Plantain NSP (5 mg/mL) significantly increased (<b>A</b>) transmucosal short circuit current (<i>I_sc</i>), with a concomitant decrease in (<b>B</b>) epithelial potential difference (PD, apical-side negative), during pre-treatment of, and blockade of translocation of S. …”

XpYp telomere end distributions in single telomere length analysis (STELA) (6 lanes/sample). by Ulrika Svenson (285527)

“…The telomere distribution in the samples from Donor 5, showing a considerable decrease in heterogeneity and a loss of the largest telomeres.…”

Data_Sheet_1_Vitamin D Status and Its Influence on the Health of Preschool Children in Hangzhou.docx by Zhaojun Chen (359184)

“…Multiple linear regression indicated that the number of caries in children increased by 0.08 per 1-ng/mL decrease in the 25(OH)D level (β = −0.08, p < 0.001).…”

Image1_Medium-term and long-term renal function changes with direct oral anticoagulants in elderly patients with atrial fibrillation.TIFF by Giuseppe Armentaro (11275959)

“…</p><p>Patients and Methods: A total of 420 AF patients were enrolled (mean age: 77.0 ± 6.0 years; 136 on WLDs and 284 on DOACs). …”

DataSheet1_Medium-term and long-term renal function changes with direct oral anticoagulants in elderly patients with atrial fibrillation.docx by Giuseppe Armentaro (11275959)

“…</p><p>Patients and Methods: A total of 420 AF patients were enrolled (mean age: 77.0 ± 6.0 years; 136 on WLDs and 284 on DOACs). …”

Image_1_Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March... by Yan Niu (1951198)

“…The D_ID and D_IR for all strains was mostly in a range of 0–2 days, with more than 75%. The range of duration for outbreaks of pre-Delta strains was the largest (median: 20 days, ranging from 1 to 61 days), and the differences were statistically significant.…”

Image_3_Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March... by Yan Niu (1951198)

“…The D_ID and D_IR for all strains was mostly in a range of 0–2 days, with more than 75%. The range of duration for outbreaks of pre-Delta strains was the largest (median: 20 days, ranging from 1 to 61 days), and the differences were statistically significant.…”

Table_1_Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March... by Yan Niu (1951198)

“…The D_ID and D_IR for all strains was mostly in a range of 0–2 days, with more than 75%. The range of duration for outbreaks of pre-Delta strains was the largest (median: 20 days, ranging from 1 to 61 days), and the differences were statistically significant.…”

Image_2_Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March... by Yan Niu (1951198)

“…The D_ID and D_IR for all strains was mostly in a range of 0–2 days, with more than 75%. The range of duration for outbreaks of pre-Delta strains was the largest (median: 20 days, ranging from 1 to 61 days), and the differences were statistically significant.…”

<i>lin-4</i> and its targets <i>lin-14</i> and <i>lin-28</i> are expressed reciprocally during larval development. by Katherine Olsson-Carter (244338)

“…In (A–C), all error bars represent standard error of the mean (S.E.M.). …”

Directed evolution of HIV-1 to utilize CD4^low target cells. by David Beauparlant (3491435)

“…<p><u>Adaptation of HIV-1 to CD4</u>^<u>low</u><u>targets <i>in vitro</i> (A, B)</u>. <b>(A)</b> Overview of stepwise adaptation to CD4^low PBMC targets and PBMC reversion cultures with normal CD4 levels and the derived envelope clones. …”

Table 1_Pre-COVID era pediatric disease incidence in Kazakhstan: regional panel data analysis of multiple disease groups (2010–2019).xlsx by Nurlan Smagulov (21510632)

“…Aqtöbe, Atyrau, and South Kazakhstan had 12–25% lower incidence compared to Zhambyl (reference), while Pavlodar and North Kazakhstan had 35–61% higher rates. A 1% increase in population density correlated with a 1.05% decrease in respiratory disease incidence (p = 0.008), whereas unemployment was linked to a 0.41% rise (p = 0.029). …”

Nutrient digestibility, nitrogen excretion, and milk production of mid-lactation Jersey × Friesian cows fed diets containing different proportions of rumen-undegradable protein by ABDUR REHMAN (10362992)

“…Cattle fed 60% RUP showed a linear decrease in N intake compared to that in the other groups. …”

Results of the sensitivity analysis. by Mifuyu Nakajima (3214149)

“…<p>Bars show the (a) mean population growth rate and (b) mean rate of allele frequency change of simulations with each of the following parameters increased or decreased by 3% (indicated by “+” and “−”, respectively) from the observed value shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0143052#pone.0143052.t001" target="_blank">Table 1</a>; “observed”: no parameters were changed; “immig”: immigration rate; “oviprob”: oviposition probability; “alfreq”: initial allele frequency; “juvsurvival”: survival until adult; “lifespan”: lifespan of adult females; “initial popl”: initial population size. …”

Thalidomide lowers BACE1 and reduces β-site cleavage of APP. by Ping He (33281)

“…<p>Representative images of Western blots showed β-secretase enzyme BACE1 bands in WT and littermate APP23 mice with/without thalidomide administration (<b>A</b>) and a significant decrease in BACE1 amount was found with thalidomide application (<b>A</b>, Mean ± SD, *<i>p</i><0.05, ANOVA test, n = 10 each group). …”

Geographic Analysis of Urologist Density and Prostate Cancer Mortality in the United States by Nengliang Yao (760915)

“…</p><p>Findings</p><p>The ordinary least squares (OLS) regression found that, on average, increasing urologist density by 1 urologist per 100,000 people resulted in an expected decrease in prostate cancer mortality of -0.499 deaths per 100,000 men (95% CI -0.709 to -0.289, p-value < 0.001), or a 1.5% decrease. …”