SDC4 controls the activity of Tiam1. by Aniko Keller-Pinter (4582792)

“…<p>(A) Schematic representation of SDC4 clones. The Ser179 of the cytoplasmic domain of SDC4 was mutated to non-phosphorylatable Ala (Ser179Ala) or, phosphomimetic Glu (Ser179Glu), respectively. …”

Image_2_The Influence of Training Load on Hematological Athlete Biological Passport Variables in Elite Cyclists.TIFF by Tiffany Astolfi (10322177)

“…(Hb) averaged 14.2 ± 0.0 (mean ± SD) g^.dL⁻¹ (range: 13.3–15.5 g·dl⁻¹) over the study with significant changes over time (P = 0.004). …”

Image_2_Predictive biomarkers and initial analysis of maternal immune alterations in postpartum preeclampsia reveal an immune-driven pathology.jpeg by Camille Couture (18464808)

“…Furthermore, changes in immune cell populations, as well as cytokine production by CD14+, CD4+, and CD8+ cells, suggested a dampened response with an exhausted phenotype including decreased IL1β, IL12, and IFNγ as well as elevated IL10. …”

Image_1_Predictive biomarkers and initial analysis of maternal immune alterations in postpartum preeclampsia reveal an immune-driven pathology.jpeg by Camille Couture (18464808)

“…Furthermore, changes in immune cell populations, as well as cytokine production by CD14+, CD4+, and CD8+ cells, suggested a dampened response with an exhausted phenotype including decreased IL1β, IL12, and IFNγ as well as elevated IL10. …”

Impact of sparsity on input-driven dynamics. by Elizabeth Herbert (13222570)

“…<p>Network responses to a step input current along a random vector <b>I</b>. …”

HDAC1 repression enhances miR-200b promoter activities and up-regulates the histone H3-acetylation level at the promoters through the Sp1-dependent pathway. by Dong-Qin Chen (639362)

“…Data were shown relative to qRT-PCR products amplified with input DNA before immunoprecipitation. p21 was used as a positive control. (F) The ChIP assays indicated that HDAC1 decreased the histone H3-acetylation level at the miR-200b promoters through the Sp1-dependent pathway. …”

Additional experiments for InR manipulations in α′β′ MBn. by Meng-Hsuan Chiang (2794081)

“…<p>(<b>A</b>) Genetic expression of <i>InR</i>^<i>CA</i> in α′β′ MBn via <i>VT57244-GAL4 > UAS-InR</i>^<i>CA</i> decreased HAB during both sated and hungry states (Satiety: <i>P</i>-values: 0.0006, <0.0001, <0.0001, and <0.0001 from left to right; Hunger: <i>P</i>-values: 0.0002, <0.0001, 0.0039, and 0.8281 from left to right). …”

PIEZO1 activity is predicted to regulate wound closure by hindering coordinated directionality. by Jinghao Chen (5145005)

“…To account for differences between control cases, data are normalized by rescaling to the mean of the corresponding control. Larger normalized wound closure indicates faster wound closure, while a smaller normalized wound closure indicates slower wound closure. …”

Plasma membrane vesicles (ROV) of cancer cells can produce ATP and PP_i with acid gradient. by Gautam Dhar (723875)

“…<p>(A) Schematic of the experiment showing assay of bead-bound ROV. …”

Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea. by Hortensia Sanchez-Calderon (186893)

“…Membranes were re-probed with β-Actin as a loading control, and for the non-phosphorylated forms of AKT and ERK1/2. …”

The actin nucleator Cobl promotes and is critical for dendritic arborization during early development of cultured primary rat cortical neurons. by Yuanyuan Ji (455424)

“…<p><b>A, B</b>, Representative MIPs of anti-MAP2-immunostained (left panels) and Imaris-reconstructed primary rat cortical neurons (right panels) that were transfected at DIV4 with either GFP (<b>A</b>) and GFP-Cobl (<b>B</b>), respectively, and fixed 40 hours later. …”

DataSheet_2_The H2S Donor Sodium Thiosulfate (Na2S2O3) Does Not Improve Inflammation and Organ Damage After Hemorrhagic Shock in Cardiovascular Healthy Swine.docx by David Alexander Christian Messerer (10307306)

“…<p>We previously demonstrated marked lung-protective properties of the H₂S donor sodium thiosulfate (Na₂S₂O₃, STS) in a blinded, randomized, controlled, long-term, resuscitated porcine model of swine with coronary artery disease, i.e., with decreased expression of the H₂S-producing enzyme cystathionine-γ-lyase (CSE). …”

Data_Sheet_1_Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2.docx by Christian Klemann (3779056)

“…In addition, an array of lymphocyte subpopulations, such as regulatory T cell, Th17-, cTFH-, NKT-, and MAIT-cell numbers were decreased. We conclude that heterozygous damaging mutations in NFKB2 represent a distinct PID entity exceeding the usual clinical spectrum of CVID. …”

Histological markers of proliferation, bone formation, and apoptosis in control and thyroxine exposed mouse cranial sutures. by R. Nicole Howie (771658)

“…Gene expression markers of proliferation (<i>Ki67</i>, <i>Ccnd1</i>, <i>Jun</i>), apoptosis (<i>Caspase 3</i>, <i>Bax</i>, <i>Bcl2</i>), and osteogenesis (<i>Runx2</i>, <i>Alp</i>, <i>Bglap</i>) from suture tissue confirm significantly increased expression for a marker of proliferation (<i>Jun</i> p = 0.03), significantly decreased expression for a marker apoptosis (<i>Bax</i> p = 0.026) and significantly increased expression for markers of osteogenesis (<i>Runx2</i> p = 0.023, <i>Alp</i> p = 0.01) with exposure to thyroxine <i>in utero</i> (n = 3 per exposure). …”

VASP was downregulated via the TNF-α-induced activation of HIF-1α during acute lung injury in vivo. by Mengjie Tang (602523)

“…The data are presented as the mean ± SEM. *p<0.05, <i>**</i>p<0.01, <i>***</i>p<0.001.…”

AjMLKL is involved in 10⁸ CFU/mL AJ01 induced lytic coelomocyte death independent on its phosphorylation. by Kaiyu Chen (11691918)

“…<p>(A) Expression patterns of AjMLKL protein and phosphorylation levels in coelomocytes after 10⁸ CFU/ml AJ01 challenge as detected using western blotting (Lower) with β-Actin as the loading control. …”

DataSheet_1_The H2S Donor Sodium Thiosulfate (Na2S2O3) Does Not Improve Inflammation and Organ Damage After Hemorrhagic Shock in Cardiovascular Healthy Swine.docx by David Alexander Christian Messerer (10307306)

“…<p>We previously demonstrated marked lung-protective properties of the H₂S donor sodium thiosulfate (Na₂S₂O₃, STS) in a blinded, randomized, controlled, long-term, resuscitated porcine model of swine with coronary artery disease, i.e., with decreased expression of the H₂S-producing enzyme cystathionine-γ-lyase (CSE). …”

Multi-organ differential gene expression changes statistically significant at hypertension onset. by Eden Hornung (20148295)

“…<p>A-B: Relative expression (–ΔΔCt) of <i>Tnf</i> (panel A, left), Il1b (panel A, middle), and <i>Ccr1</i> (panel A, right) in kidney as well as of <i>Ccr5</i> (panel B, left), <i>Ilrn</i> (panel B, middle), and <i>Ltb4r</i> (panel B, right) in kidney. …”

Cell wall components are altered in the <i>mar1Δ</i> cell wall. by Shannon K. Esher (720288)

“…<p>(A) The <i>mar1Δ</i> cell wall has increased chitin and chitosan staining by flow cytometry, but <i>mar1Δ</i> staining for α-glucans, β-(1,3)-glucan, and mannoproteins is limited above baseline. …”

Figure 5 from Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma by Yichi Zhang (20458547)

“…Experimental groups are FAK-WT saline (green), FAK-WT plus CP (red), FAK-NLS⁻ saline (blue), and FAK-NLS⁻ + CP (violet). Values are means ± SD (<i>n</i> = 8, *, <i>P</i> < 0.05). <b>C,</b> Experimental schematic (similar as described in <b>A</b>) with decreased and more frequent cisplatin (2 mg/kg) administration over a longer experimental period. …”