Ribosome footprinting and polysome profiling reveal DUX4 suppressive effects on translation efficiency. by Danielle C. Hamm (4693915)

“…(<b>I</b>) Log2 fold-change in polysome abundance of MHC-I mRNAs, iProteasome subunits, select TOP mRNAs, and myogenic factors. Data represent mean ± SD of biological replicates, <i>n =</i> 3; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002317#pbio.3002317.s012" target="_blank">S4 Data</a>. …”

<i>pals-17</i> mutant phenotypes are fully <i>pals-16</i>-dependent. by Vladimir Lažetić (5047592)

“…<p>(A, B) <i>pals-16</i> RNAi decreases <i>pals-5</i>p::GFP expression in <i>pals-17 pals-20</i> mutants. …”

Effects of the Pgp inhibitor tariquidar (TQ; 0.5 µM) in three functional assays, in which alterations in Pgp efflux are indirectly measured by determining intracellular concentrati... by Andreas Noack (519906)

“…<p>Data are shown as mean ± SEM of three experiments; all experiments with one uptake assay were performed together to avoid inter-experiment variation. …”

Real-world cost-effectiveness of pan-genotypic Sofosbuvir-Velpatasvir combination versus genotype dependent directly acting anti-viral drugs for treatment of hepatitis C patients i... by Yashika Chugh (7325960)

“…Compared to scenario I, scenario III leads to an increase in QALYs by 0.44 (0.14 to 1.01) per person, and is cost-neutral. While the mean cost difference between scenario III and I is—₹ 2,676 per patient, it ranges from a cost saving of ₹ 14,835 to incurring an extra cost of ₹ 3,456 per patient. …”

Does proximity of women to facilities with better choice of contraceptives affect their contraceptive utilization in rural Ethiopia? by Solomon Shiferaw (3158184)

“…The main outcome variable was individual use of a contraceptive method for married women in rural Ethiopia. …”

Repositioning of the global epicentre of non-optimal cholesterol by Taddei, Cristina

“…However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. …”
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High sucrose shortened <i>Drosophila</i> life span and was associated with increased cardiac arrhythmia and heart deterioration. by Jianbo Na (12352)

“…Arrhythmias observed in M-mode can be quantified as arrhythmia index, which is the standard deviation of all heart periods in each record normalized to the median heart period for each fly. Mean ± SE are shown. At week three, a significant increase in arrhythmia index was observed in HSD fed flies (0.44) compared to low sucrose fed flies (0.16) (*P = 1.54E-17 by F-test). …”

Vertical zonation and functional diversity of fish assemblages revealed by ROV videos at oil platforms in The Gulf by Ben-Hamadou, Radhouan

“…These results suggest that the vertical zonation pattern does not change, or only changes slightly, on a daily basis. The mean centers of mass of the most abundant fish species did not overlap, likely due to potential competition or niche differences. …”
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TRPC channels augment the presynaptic Ca²⁺-rise upon HFS. by Yvonne Schwarz (7406756)

“…<p>(A) Exemplary images of neurons expressing the vesicular protein SybII-mRFP (left) and Synaptophysin-GCaMP6s (SyGCaMP6s, middle). …”

Loss of Fhl1b activity enhances induction of pancreatic cells and compromises liver specification. by Jin Xu (31283)

“…<p>(A-D) Whole-mount <i>in situ</i> hybridization showing the expression of <i>hhex</i> (A and B) and <i>pdx1</i> (C and D), comparing control embryos (A and C) and <i>fhl1b</i> morphants (B and D) at 30 hpf. …”

ROCK inhibition with Y-27632 attenuates prion disease in mice. by Aurélie Alleaume-Butaux (446780)

“…Note that mouse infection with 22L strain is associated with decreased PrP α-cleavage at the expense of PrP β-cleavage that generates C2 fragment [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005073#ppat.1005073.ref068" target="_blank">68</a>, <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005073#ppat.1005073.ref069" target="_blank">69</a>]. n = 5 for each condition. …”

Characterizing the connectivity of in vitro neuronal networks. by Christian Donner (3663007)

“…<b>I</b> All inference methods yielded an over-representation of triplet motifs (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011964#pcbi.1011964.g002" target="_blank">Fig 2</a> for motif ID legend), but with slight differences across methods. …”

ERK activation increases sleep. by William M. Vanderheyden (231718)

“…Data are presented as mean ± SEM, (* = p < 0.05). <i>E</i>, RU fed <i>+</i>;<i>UAS-ERK^SEM/+</i> ;<i>GSw-elav/+</i> showed increased activity during waking (ZT1-ZT12) compared to vehicle fed controls; A 2(RU+, RU-) X 12(Hour) ANOVA reveals a significant main effect of drug <i>F</i>_(1,600) = 88.47, <i>P</i> = 1.08 E-19] (n = 26/ group). …”

Study group background characteristics. by Zicheng Hu (3825313)

“…The dashed horizontal lines in <b>Fig 1K</b>–<b>1O</b> indicate the mean +2 SD of the uninfected, seronegative (<b><i>HIV-</i></b>) control group in the measured variable as a rough estimate of their upper normal limit and as a visual guide to compare groups; this convention is also used in the Olink CSF protein measurement figures showing the group profiles in subsequent figures. …”

Arl2 KD affects mNPC proliferation in vitro. by Dongliang Ma (19415424)

“…(<b>B</b>) Bar graphs showing Arl2 expression levels at E12, 1.00 ± 0.00 A.U.; E13, 0.91 ± 0.10 A.U.; E14, 0.57 ± 0.17 A.U.; E16, 0.41 ± 0.16 A.U.; P1, 0.24 ± 0.09 A.U.; P7, 0.18 ± 0.06 A.U. …”

ClpL and PsaB are involved in the pneumococcal stress response needed for the viral-bacterial synergism. by Nicolás M. Reinoso-Vizcaíno (9239763)

“…Expression levels of PsaB of different conditions were relativized to PsaB levels of wt strain grown at pH 7. Values represents mean ± SD of three replicates. Data were analyzed using Perseus software [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008761#ppat.1008761.ref086" target="_blank">86</a>]. …”

ERR2/3 expressed by gamma motor neurons is required for normal locomotion and precision movements. by Mudassar N. Khan (14290428)

“…Data are presented as mean ± SEM. <i>N</i> = # of mice, <i>n</i> = # of 1a afferents. …”

Table_2_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.docx by Jie Tao (227070)

“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm², which was significantly decreased to 5.85 ± 0.95 mm² by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”

image_2_Type I and III Interferon Productions Are Impaired in X-Linked Agammaglobulinemia Patients Toward Poliovirus but Not Influenza Virus.jpeg by Anderson Dik Wai Luk (5618996)

“…Background<p>X-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by Bruton’s tyrosine kinase (BTK) mutation. …”

Image_3_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.tif by Jie Tao (227070)

“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm², which was significantly decreased to 5.85 ± 0.95 mm² by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”