PARP1-cGAS-NF-κB pathway of proinflammatory macrophage activation by extracellular vesicles released during <i>Trypanosoma cruzi</i> infection and Chagas disease - Fig 2 by Subhadip Choudhuri (8741193)

“…<p><b>(A-F) <i>Parp1</i></b>^{<b><i>-/-</i></b>}<b>primary Mφ exhibit decreased cytokines’ expression in response to TEv stimulation</b>. …”

DataSheet_1_Evidence on Efficacy and Safety of Chinese Medicines Combined Western Medicines Treatment for Breast Cancer With Endocrine Therapy.docx by Lu Li (14069)

“…Background<p>Breast cancer, a malignant disorder, occurs in epithelial tissue of the breast glands and ducts. …”

Cul7^Fbxw8 triggers the ubiquitination and degradation of Grasp65 to promote Golgi morphogenesis and drive dendrite elaboration in neurons. by Nadia Litterman (221903)

“…(D) Granule neurons transfected at DIV2 with the U6/grasp65 or control U6 plasmid together with the expression plasmid encoding Grasp65-WT, Grasp65-Res, or control vector were analyzed as in (A). Quantification of total dendrite length revealed that Grasp65-Res but not Grasp65-WT significantly decreased dendrite length in the background of Grasp65 RNAi (<i>p<</i>0.01, ANOVA followed by Bonferroni post hoc test; total neurons measured = 409). …”

Behavioral characterization of <i>Del-Dup</i> cohorts. by Thomas Arbogast (1783087)

“…<p><b>(A)</b> Circadian activity test. Graphs plot the spontaneous ambulatory activity (count) and the vertical activity/rears (count) during dark and light phases. …”

Effect of N-glycosylation on MUC16 transformation. by Thapi D. Rao (737875)

“…However, MUC16^3(N—A)c1143T3 transfectants did not show any significance over phrGFP vector control 3T3 cells, indicating that the mutations of N-glycosylation dramatically decreased <i>in vivo</i> tumor growth and invasion.…”

Quantitative scoring of collagen II, MMP-13 and ICAM-1 immunohistochemistry. by Julia Lorenz (626379)

“…<p>Medial parts of frontal sections of right knee joints from WT and Mc1re/e mice of non-operated (non-op) 11 weeks old and 6 months old animals, and of mice 4 and 8 weeks after osteoarthritis induction (post operation (p.o.)) were scored after staining. 1-3 sections of right knees (DMM) were scored histological according to the scoring system illustrated in Tab. 1 for collagen II, in Tab. 2 for MMP-13 and in Tab. 3 for ICAM-1 staining. A) Compared to non-operated controls collagen II stained cartilage area of WT knee joints is decreased 4 weeks (p = 0.0079) and 8 weeks (p = 0.0043) after OA-induction as well as in non-operated 6 month old animals (p = 0.0159). …”

Induced acetylation of the replication fork increases DNA damage. by Benilde García-de Teresa (17838878)

“…<p><b>(A)</b> For aniPOND assays cells were treated with SAHA [1 μM] for 24 hours or left untreated (yellow arrow), labeled with an EdU [10 μM] pulse for 15 mins (blue arrow), and harvested. …”

Table5_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Table_1_Is it time for class I recommendation for sodium-glucose cotransporter-2 inhibitors in heart failure with mildly reduced or preserved ejection fraction?: An updated systema... by Sukrit Treewaree (14577911)

“…</p>Results<p>Sixteen studies (9 recent RCTs) were included, and a total of 16,710 HFmrEF or HFpEF patients were enrolled. …”

Increased Phagocytic Activity and Removal of Degenerated Myelin in the Spinal Cord by TREM2-Transduced Myeloid Cells by Kazuya Takahashi (69459)

“…<div><p>(A) Immunostaining of macrophages (MAC3), T cells (CD3), degenerated MBP (dMBP), and Lamp2 in the spinal cord of EAE-diseased mice at day 2 after injection of TREM2-transduced myeloid cells (TREM-BM-MC), GFP-transduced myeloid cells (GFP-BM-MC), or vehicle control (PBS). …”

Table1_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Image_1_Gpr174 Knockout Alleviates DSS-Induced Colitis via Regulating the Immune Function of Dendritic Cells.tif by Wei Wei (21173)

“…The flow cytometry was used to detect the infiltrations of T cells and DCs, the mean fluorescence intensity (MFI) of CD80, CD86, CD40, and major histocompatibility complex-II (MHC-II). …”

Image_1_Is it time for class I recommendation for sodium-glucose cotransporter-2 inhibitors in heart failure with mildly reduced or preserved ejection fraction?: An updated systema... by Sukrit Treewaree (14577911)

“…</p>Results<p>Sixteen studies (9 recent RCTs) were included, and a total of 16,710 HFmrEF or HFpEF patients were enrolled. …”

Table5_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Image2_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.tiff by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Table1_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Image3_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.tif by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Table3_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Table3_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…Furthermore, the epidermal thickness decreased more after SHI or DMA treatment than in the control group (MD = -34.42, 95%CI [-41.25, -27.59], p < 0.00001, I² = 93%). …”

Data_Sheet_1_Is it time for class I recommendation for sodium-glucose cotransporter-2 inhibitors in heart failure with mildly reduced or preserved ejection fraction?: An updated sy... by Sukrit Treewaree (14577911)

“…</p>Results<p>Sixteen studies (9 recent RCTs) were included, and a total of 16,710 HFmrEF or HFpEF patients were enrolled. …”